Adefovir dipivoxil An antiviral acyclic nucleoside phosphonate (ANP) analog

Adefovir dipivoxil (CAS 142340-99-6)

Adefovir dipivoxil | CAS 142340-99-6 is rated 5.0 out of 5 by 1.
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Synonym: 9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine
Application: An antiviral acyclic nucleoside phosphonate (ANP) analog
CAS Number: 142340-99-6
Purity: ≥99%
Molecular Weight: 501.47
Molecular Formula: C20H32N5O8P
* Refer to Certificate of Analysis for lot specific data (including water content).
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Adefovir dipivoxil is an antiviral acyclic nucleoside phosphonate (ANP) analog. Works by blocking reverse transcriptase.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in ethanol (100 mg/ml at 25° C), DMSO (100 mg/ml at 25° C), water (<1 mg/ml at 25° C), and methanol.
Storage :
Store at -20° C
Melting Point :
100° C
Boiling Point :
~641.0° C at 760 (Predicted)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.57 (Predicted)
IC50 :
CEM-SS: EC5050 = 40 nM (human); Hepatitis B virus: IC50 = 330 nM; Vero: IC50 = 0.6 µM (grivet); Vaccinia virus: IC50 = 5.1 µM; Cowpox virus: IC50 = 13 µM
pK Values :
pKb: 4.16 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
UA2459362
PubChem CID :
60871
Merck Index :
14: 151
MDL Number :
MFCD00869897
SMILES :
CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from excellent Wonderful and suitable for cell assay at different concentration gradient.
Date published: 2016-11-03
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