ABN-CBD is a neurobehaviorally inactive cannabinoid that acts as a selective agonist for GPR55 (EC50 values are 2.5, >30 and >30 μM at GPR55, CB1 and CB2 receptors respectively). ABN-CBD increases the phosphorylation of protein kinases in, and migration of, human umbilical vein endothelial cells.
1. Jarai, Z., et al. 1999. Proc. Natl. Acad. Sci. U.S.A. 96: 14136-14141. PMID: 10570211 2. Ho. W.S. and Hiley, C.R., 2003. Br. J. Pharmacol. 138: 1320-1332. PMID: 12711633 3. Mo, F.M., et al. 2004. Eur. J. Pharmacol. 489: 21-27. PMID: 15063151 4. Ryberg, E., et al. 2007. Br. J. Pharmacol. 152: 1092-1101.PMID: 17876302
A solution in methyl acetate
Soluble in methyl acetate, ethanol (~35 mg/ml), DMSO (~35 mg/ml), DMF (~35 mg/ml), and DMSO:PBS (1:3, pH 7.2) (0.25 mg/ml).
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