ABD-FA fluorogenic reagent for labelling thiol compounds

ABD-F (CAS 91366-65-3)

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Synonym: 4-Fluoro-7-sulfoamoylbenzofurazan; 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole
Application: A fluorogenic reagent for labelling thiol compounds
CAS Number: 91366-65-3
Molecular Weight: 217.17
Molecular Formula: C6H4FN3O3S
* Refer to Certificate of Analysis for lot specific data (including water content).
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ABD-F is a highly reactive fluorogenic reagent for labelling thiol compounds. Selectively labels protein cysteine residues without side chain modification or N-terminal blockage. Potent vasorelaxant.


References

1. Toyo'oka, T. and Imai, K. 1985. Anal. Chem. 57: 1931-1937. PMID: 4037347
2. Toyo'oka, T., et al. 1986. Biomed. Chromatogr. 1: 15-20. PMID: 3506813
3. Imai, K. and Toyo'oka, T. 1987. Meth. Enzymol. 143: 67-75. PMID: 3155390

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in 1 N NH4OH (50 mg plus 1 mL in 1 N NH4OH), acetonitrile (10 mg/1 ml), water, methanol, and DMSO.
Storage :
Store at -20° C
Melting Point :
143-145° C
Boiling Point :
~408.78° C at 760 mmHg (Predicted)
Density :
1.72 g/cm3 (Predicted)
Refractive Index :
n20D 1.63 (Predicted)
Fluoresence :
λex 389 nm, λem 513 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
122067
MDL Number :
MFCD00036687
Beilstein Registry :
5035147
SMILES :
C1=C(C2=NON=C2C(=C1)S(=O)(=O)N)F

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Certificate of Analysis

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ABD-F  Product Citations

See how others have used ABD-F. Click on the entry to view the PubMed entry .

Citations 1 to 6 of 6 total

PMID: # 20569301  Bousquet, M. et al. 2010. J. Neurochem. 114: 1651-1658.

PMID: # 18692218  Dazy, M. et al. 2008. Chemosphere. 73: 281-290.

PMID: # 18071254  Takeda, M. et al. 2007. Biosci. Biotechnol. Biochem. 71: 2992-2998.

PMID: # 12199709  Tenno, M. et al. 2002. Eur. J. Biochem. 269: 4308-4316.

PMID: # 11159542  Namour, F. et al. 2001. Blood. 97: 1092-1098.

PMID: # 10876010  Ono, H. et al. 2000. Clin. Chim. Acta. 298: 135-143.

Citations 1 to 6 of 6 total
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