8-Hydroxyquinoline A monoprotic bidentate chelating agent and dye

8-Hydroxyquinoline (CAS 148-24-3)

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Synonym: Oxine; 8-Quinolinol; 8-Oxychinolin
Application: A monoprotic bidentate chelating agent and dye
CAS Number: 148-24-3
Purity: ≥99%
Molecular Weight: 145.17
Molecular Formula: C9H7NO
* Refer to Certificate of Analysis for lot specific data (including water content).
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8-Hydroxyquinoline is a monoprotic bidentate chelating agent The reaction of 8-hydroxyquinoline with aluminium(III) results in Alq3, a common component of organic light-emitting diodes (OLED's). Variations in the substituents on the quinoline rings affect its luminescent properties. 8-Hydroxyquinoline is employed in precipitating and separating metals, the preparation of fungicides, and as a dye.


1. Montes, V.A., er al. 2006. Chemistry. 12: 4523-4535. PMID: 16619313
2. Katakura, R., et al. 2006. Inorg Chem. 45: 5730-5732. PMID: 16841973

Appearance :
Physical State :
Solubility :
Soluble in acetone, ethanol, chloroform, and benzene. Insoluble in water.
Storage :
Store at room temperature
Melting Point :
70-73° C (lit.)
Boiling Point :
267° C (lit.) at 752 mmHg
Density :
1.03 g/cm3 at 20° C
Refractive Index :
n20D 1.69 (Predicted)
IC50 :
BChE: IC50 > 100 nM (human); AChE: IC50 > 100 nM (human); FM3A: IC50 = 2.1 µM (mouse); MetAP-2: IC50 = 5.6 µM (human); MetAP-1: IC50 = 21.5 µM (human).
Ki Data :
Thermolysin: Ki= 214 µM (bacillus thermoproteolyticus)
pK Values :
pKa: 5.06 (Predicted), pKb: 9.81 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 4843
MDL Number :
EC Number :
Beilstein Registry :

Download SDS (MSDS)

Certificate of Analysis

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