8-Anilino-1-naphthalenesulfonic acid is a fluorescent dye that binds with high affinity to hydrophobic surfaces of proteins. It is commonly used to study molecular assemblies of surfactants and amphiphilic polymers because a blue shift of the emission maximum indicates the fluorophore is located in less polar media.
R.A. Muesing, T. Nishida, Disruption of low- and high-density human plasma lipoproteins and phospholipid dispersions by 1-anilinonaphthalene-8-sulfonate. Biochemistry 10, 2952, (1971); U.P. Andley, B. Chakrabarti Biochemistry 20, 1687, (1981); J.J. Ewbank, T.E. Creighton Biochemistry 32, 3694, (1993); J.A. Vinson, J.E. Hooyman, For the sensitive detection of neutral lipids and phospholipids after TLC. J. Chromatogr. 135, 226, (1977)
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