8-Anilino-1-naphthalenesulfonic acidA fluorescent with high affinity towards hydrophobic surfaces of proteins

8-Anilino-1-naphthalenesulfonic acid (CAS 82-76-8)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 89ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: 1,8-ANS; N-Phenyl peri acid
Application: A fluorescent with high affinity towards hydrophobic surfaces of proteins
CAS Number: 82-76-8
Purity: ≥95%
Molecular Weight: 299.34
Molecular Formula: C16H13NO3S
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

8-Anilino-1-naphthalenesulfonic acid is a fluorescent dye with high affinity towards hydrophobic surfaces of proteins. It is useful for determining the affinity of hydrophobic ligands to their corresponding binding proteins. 8-Anilino-1-naphthalenesulfonic acid undergoes a blue shift and fluorescence increases when it binds to non-polar regions of a protein surface or membranes. Used as a probe to monitor protein-folding.

Appearance :
Crystalline or powder
Physical State :
Solid
Solubility :
Soluble in DMF: 50 mg/ml
Storage :
Store at -20° C
Melting Point :
215-217° C (lit.)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.71 (Predicted)
IC50 :
PDIA2: EC5050 = 2.95 µM (human); Dengue virus type 2 NS3 protein: IC50 >100 µM; Beta-lactamase AmpC: IC50 >1.6 mM
Ki Data :
A-FABP: Ki= 1 µM (human); choactase: Ki= 200 µM (human)
Fluoresence :
λex 371 nm, λem 480 nm in methanol
pK Values :
pKa: 0.19 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
1369
Merck Index :
14: 661
MDL Number :
MFCD00003998
EC Number :
201-438-7
Beilstein Registry :
1843887
SMILES :
C1=CC=C(C=C1)NC2=CC=CC3=C2C(=CC=C3)S(=O)(=O)O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

8-Anilino-1-naphthalenesulfonic acid  Product Citations

See how others have used 8-Anilino-1-naphthalenesulfonic acid. Click on the entry to view the PubMed entry .

Citations 1 to 5 of 5 total

PMID: # 16608195  Huet, AC. et al. 2006. J. Agric. Food Chem. 54: 2822-2827.

PMID: # 15890362  Li, Y. et al. 2005. J. Mol. Biol. 349: 839-846.

PMID: # 12782291  Jouhet, J. et al. 2003. FEBS Lett. 544: 63-68.

PMID: # 12123027  Suzuki, M. et al. 2002. Chem. Commun. (Camb.). 884-885.

PMID: # 10664456  Mondola, P. et al. 2000. FEBS Lett. 467: 57-60.

Citations 1 to 5 of 5 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 85ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 32ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.