8-Aminoguanosine is a potent inhibitor of purine nucleoside phosphorylase (PNP).
1. Kazmers, I S., et al., 1981. Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts. Science (New York, N.Y.). 214(4525): 1137-9. PMID: 6795718
2. Chern, J W., et al., 1993. Nucleosides. 5. Synthesis of guanine and formycin B derivatives as potential inhibitors of purine nucleoside phosphorylase. Journal of medicinal chemistry. 36(8): 1024-31. PMID: 8478902
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