7,8-Dihydroxyflavone is a tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor with a Kd value of 320 nM. It also inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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What is the limit of solubility of this compound (7,8-Dihydroxyflavone) in water?
Is it soluble in 0.9% saline?
We have been trying to get it into solution with 20% DMSO diluted in saline and becomes milky white with addition of saline at [5mg/ml].
Asked by: rs6265
Thank you for your question. This information can vary for each lot. Please contact technical service for assistance with dissolving this biochemical.
Answered by: Tech Service
Date published: 2019-02-27
Asked by: Kelly Ho
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot.
Rated 5 out of
FengFeng, P. et al. (PubMed 26343602) reported that 7,8-Dihydroxyflavone reduces sleep during dark phase and suppresses orexin A but not orexin B in mice. -SCBT Publication Review
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