7,8-Dihydroxyflavone is a tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor with a Kd value of 320 nM. It also inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro.
Soluble in water (Partly miscible), alkali hydroxide solutions, and DMSO (24 mg/ml).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Download SDS (MSDS)
Certificate of Analysis
Adobe Acrobat Reader is required to reliably view, print and comment on PDF documents
What is the limit of solubility of this compound (7,8-Dihydroxyflavone) in water?
Is it soluble in 0.9% saline?
We have been trying to get it into solution with 20% DMSO diluted in saline and becomes milky white with addition of saline at [5mg/ml].
Asked by: rs6265
Thank you for your question. This information can vary for each lot. Please contact technical service for assistance with dissolving this biochemical.
Answered by: Tech Service
Date published: 2019-02-15
Asked by: Kelly Ho
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot.
Rated 5 out of
FengFeng, P. et al. (PubMed 26343602) reported that 7,8-Dihydroxyflavone reduces sleep during dark phase and suppresses orexin A but not orexin B in mice. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.