6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein.
Karran P. Br Med Bull 79-80: 153-70 (2006). Sartorelli AC, Booth BA. Cancer Res. 25: 1393-40 (1965).
Soluble in DMSO (100 mM).
Store at room temperature
>300° C (lit.)(dec.)
~460.7° C at 760 mmHg (Predicted)
~2.1 g/cm3 (Predicted)
n20D 2.07 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
UN 2811, Class 6.1, Packing group III
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Rated 5 out of
LaDuke et alLaDuke et al. (PubMed ID 26111096) found that 6-Thioguanine reduced canine hepatocyte viability in and a time- and concentration-dependent manner. -SCBT Publication Review
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