6-Thioguanine 6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities.

6-Thioguanine  (CAS 154-42-7)

6-Thioguanine is rated 5.0 out of 5 by 1.
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Synonym: 2-Amino-6-purinethiol
Application: An immunosuppressive, anti-neoplastic, and anti-cancer
CAS Number: 154-42-7
Molecular Weight: 167.19
Molecular Formula: C5H5N5S
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
6-Thioguanine sc-205587 250 mg $40.00
6-Thioguanine sc-205587A 500 mg $69.00

6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein.


References

Karran P. Br Med Bull 79-80: 153-70 (2006). Sartorelli AC, Booth BA. Cancer Res. 25: 1393-40 (1965).

Physical State :
Solid
Derived From :
Synthetic
Solubility :
Soluble in DMSO (100 mM).
Storage :
Store at room temperature
Melting Point :
>300° C (lit.)(dec.)
Boiling Point :
~460.7° C at 760 mmHg (Predicted)
Density :
~2.1 g/cm3 (Predicted)
Refractive Index :
n20D 2.07 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
UP0740000
Transport :
UN 2811, Class 6.1, Packing group III
PubChem CID :
2723601
Merck Index :
14: 9337
MDL Number :
MFCD00233553
EC Number :
205-827-2
Beilstein Registry :
157765
SMILES :
C1=NC2=C(N1)C(=S)N=C(N2)N

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from LaDuke et al LaDuke et al. (PubMed ID 26111096) found that 6-Thioguanine reduced canine hepatocyte viability in and a time- and concentration-dependent manner. -SCBT Publication Review
Date published: 2015-06-09
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