5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0): sc-352647...

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5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0) (CAS 26172-55-4)

5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI 2.0) | CAS 26172-55-4 is rated 5.0 out of 5 by 1.

See product citations (2)

Synonym: Methylchloroisothiazolinone; 2-Methyl-5-chloro-3-isothiazolone; CMI

Application: An antimicrobial agent

CAS Number: 26172-55-4

Purity: Active Ingredient >14%

Molecular Weight: 149.60

Molecular Formula: C₄H₄ClNOS

Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.

* Refer to Certificate of Analysis for lot specific data (including water content).

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5-Chloro-2-methyl-4-isothiazolin-3-one (CMI) is an antimicrobial agent. The ratio of CMI/MI is 2.5 – 4.0.

Formulation :

> 14% in water

Physical State :

Liquid

Storage :

Store at room temperature

Melting Point :

-21° C

Boiling Point :

100° C

Density :

1.25 g/mL(14% aq.)

Refractive Index :

1.378

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Transport :

UN 1760, Class 8, Packing group II

PubChem CID :

33344

MDL Number :

MFCD00792550

EC Number :

247-500-7

SMILES :

CN1C(=O)C=C(S1)Cl

Download SDS (MSDS)

Certificate of Analysis

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5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0) Product Citations

See how others have used 5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 25809859 Yamamoto, Y. et al. 2015. J Appl Toxicol. 35: 1348-60.

PMID: # 24928155 Fujita, M. et al. J Pharmacol Toxicol Methods. 70: 94-105.

Citations 1 to 2 of 2 total

Hello, my question is, in the topicof the CoA it is written that only CMI is contain in the Solution. But at the End of the CoA, you see the Information that CMI and MI is contain. What the correct composition of this solution?

Asked by: MSBfR

Thank you very much for your question. sc-352647 (5-Chloro-2-methyl-4-isothiazolin-3-one, CAS 26172-55-4) is an aqueous solution containing a mixture of 5-Chloro-2-methyl-4-isothiazolin-3-one (CMI) and 2-Methyl-4-isothiazolin-3-one (MI). It is soluble in methanol. For any further questions please contact our European Support Office in Germany directly. You can reach us by phone at: +49 6221 4503 0, by email at: europe@scbt.com or by live chat directly on our website, www.scbt.com We are happy to assist you.

Answered by: Technical Support Europe

Date published: 2019-01-23

hello.., my question is straight: i like to use CMI (5-chloro-2 methyl-4 isothiazolin-3-one, in making a cosmetic based WATER GEL along with TEA and carbomer. please advice

Asked by: veer

Thank you for your question. We do not recommend or support the use of this chemical for therapeutic, diagnostic, or other non-research use such as in the manufacturing or testing of cosmetic products.

Answered by: Technical Support

Date published: 2017-05-15

What is the composition?

Asked by: chemsd02

Thank you for your question. sc-352647 (5-Chloro-2-methyl-4-isothiazolin-3-one, CAS 26172-55-4) is an aqueous solution containing a mixture of 5-Chloro-2-methyl-4-isothiazolin-3-one (CMI) and 2-Methyl-4-isothiazolin-3-one (MI). It is soluble in methanol.

Answered by: Chemical Support 10

Date published: 2017-03-20

There is still precipitation in this product, is it still good?

Asked by: hawkeye11

Thank you for your question. In 5-Chloro-2-methyl-4-isothiazolin-3-one (CMI), sc-352647, you may see small precipitates in the liquid which are the CMI and MI organic ingredients. These may sometimes not fully dissolve since the product is in aqueous solution and needs to stay at these concentrations. The product is still usable for its biological and chemical purposes.

Answered by: TechService7

Date published: 2017-01-20

Good morning :-) Is this diluted in water now? It seems to by looking at the SDS - but according to my lab mates, this was previously dissolved in methanol. I notice that it comes out of solution rather easily. Is vortexing sufficient before use? Thanks!

Asked by: Jenn

Thank you for your question. Yes, this is an aqueous solution, it is ideal if you vortex or sonicate it before use.

Answered by: Technical Support

Date published: 2016-09-23

Rated 5 out of 5 by JM from Various publications cite 5 Various publications cite 5-Chloro-2-methyl-4-isothiazolin-3-one (CMI, Methylchloroisothiazolinone) as a preservative with antibacterial and anti-fungal effects. It is effective against gram-positive and gram-negative bacteria, yeast, and fungi. -SCBT Publication Review

Date published: 2015-01-09

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5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0) (CAS 26172-55-4)

QUICK LINKS

Download SDS (MSDS)

Certificate of Analysis

5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0) Product Citations

Hello, my question is, in the topicof the CoA it is written that only CMI is contain in the Solution. But at the End of the CoA, you see the Information that CMI and MI is contain. What the correct composition of this solution?

hello.., my question is straight: i like to use CMI (5-chloro-2 methyl-4 isothiazolin-3-one, in making a cosmetic based WATER GEL along with TEA and carbomer. please advice

What is the composition?

There is still precipitation in this product, is it still good?

Good morning :-) Is this diluted in water now? It seems to by looking at the SDS - but according to my lab mates, this was previously dissolved in methanol. I notice that it comes out of solution rather easily. Is vortexing sufficient before use? Thanks!

5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0) (CAS 26172-55-4)

QUICK LINKS

Download SDS (MSDS)

Certificate of Analysis

5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0) Product Citations

Hello, my question is, in the topicof the CoA it is written that only CMI is contain in the Solution. But at the End of the CoA, you see the Information that CMI and MI is contain. What the correct composition of this solution?

hello.., my question is straight: i like to use CMI (5-chloro-2 methyl-4 isothiazolin-3-one, in making a cosmetic based WATER GEL along with TEA and carbomer. please advice

What is the composition?

There is still precipitation in this product, is it still good?

Good morning :-) Is this diluted in water now? It seems to by looking at the SDS - but according to my lab mates, this was previously dissolved in methanol. I notice that it comes out of solution rather easily. Is vortexing sufficient before use? Thanks!

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