5,7-Dichloro-8-quinolinol A synthetic antibacterial compound

5,7-Dichloro-8-quinolinol (CAS 773-76-2)

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Synonym: Chloroxine
Application: A synthetic antibacterial compound
CAS Number: 773-76-2
Purity: ≥98%
Molecular Weight: 214.05
Molecular Formula: C9H5Cl2NO
* Refer to Certificate of Analysis for lot specific data (including water content).
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Physical State :
Solubility :
5% IN DIOXANE; CLEAR TO SLIGHTLY HAZY,YELLOW OR GREEN SOLUTION.Soluble in benzene, acetone. Slightly soluble in acetic acid. Readily soluble in sodium and potassium hydroxides and in acids, forming solutions. Very slightly soluble in: Ethanol Chloroform.
Storage :
Store at room temperature
Melting Point :
178-180° C (lit.)
Boiling Point :
~354.7° C at 760 mmHg (Predicted)
Density :
~1.5 g/cm3 (Predicted)
Refractive Index :
n20D 1.70 (Predicted)
IC50 :
Arachidonate 5-lipoxygenase: IC50 = 3.6 µM (human); Arachidonate 12-lipoxygenase: IC50 = 1.9 µM (human); Arachidonate 15-lipoxygenase, type II: IC50 = 28 µM (human); Arachidonate 15-lipoxygenase: IC50 = 2.4 µM (human); Kappa opioid receptor: IC50 = 4.56 µM (human); Streptococcus sp. 'group A': EC5050 = 258 nM (Streptococcus sp. 'group A'); Streptococcus: EC5050 = 3306 nM (Streptococcus); Beta-galactosidase: EC5050 = >31.5 µM (Escherichia coli); Streptokinase A: EC5050 = 148 nM (Streptococcus pyogenes serotype M1); Delta opioid receptor: IC50 >32 µM (human)
pK Values :
pKa: 2.30, pKb: 7.20
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 2175
MDL Number :
EC Number :
Beilstein Registry :

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Certificate of Analysis

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