(4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol (CAS 511-15-9)
See product citations (1)
QUICK LINKS
(4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol is a synthetic organic compound that is of interest in the field of organic and synthetic chemistry research. This compound′s complex structure, characterized by a trans-fused ring system and multiple chiral centers, makes it a useful subject for studies in stereoselective synthesis and chiral resolution techniques. Researchers focus on its synthetic pathways to develop new methods for constructing phenanthrene derivatives, which are important in the synthesis of natural products and novel materials. The presence of the isopropyl group and the alcohol functionality in (4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol allows for further derivatization, making it a versatile intermediate for the preparation of more complex organic molecules. Additionally, its structure is studied for its physical properties, such as optical activity, which is relevant in the development of optically active materials and in the field of molecular electronics.
(4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol (CAS 511-15-9) References
- Potentiation of methicillin activity against methicillin-resistant Staphylococcus aureus by diterpenes. | Nicolson, K., et al. 1999. FEMS Microbiol Lett. 179: 233-9. PMID: 10518721
- Antibacterial activity of totarol and its potentiation. | Kubo, I., et al. 1992. J Nat Prod. 55: 1436-40. PMID: 1453180
- Totarol inhibits bacterial cytokinesis by perturbing the assembly dynamics of FtsZ. | Jaiswal, R., et al. 2007. Biochemistry. 46: 4211-20. PMID: 17348691
- The antifungal compound totarol of Thujopsis dolabrata var. hondai seeds selects for fungi on seedling root surfaces. | Yamaji, K., et al. 2007. J Chem Ecol. 33: 2254-65. PMID: 18026796
- Antiparasitic, nematicidal and antifouling constituents from Juniperus berries. | Samoylenko, V., et al. 2008. Phytother Res. 22: 1570-6. PMID: 19067375
- Synthesis, biological evaluation and mechanistic studies of totarol amino alcohol derivatives as potential antimalarial agents. | Tacon, C., et al. 2012. Bioorg Med Chem. 20: 893-902. PMID: 22196513
- Inhibitory effect of totarol on exotoxin proteins hemolysin and enterotoxins secreted by Staphylococcus aureus. | Shi, C., et al. 2015. World J Microbiol Biotechnol. 31: 1565-73. PMID: 26193949
- The synergy of berberine chloride and totarol against Staphylococcus aureus grown in planktonic and biofilm cultures. | Guo, N., et al. 2015. J Med Microbiol. 64: 891-900. PMID: 26272283
- Totarol prevents neuronal injury in vitro and ameliorates brain ischemic stroke: Potential roles of Akt activation and HO-1 induction. | Gao, Y., et al. 2015. Toxicol Appl Pharmacol. 289: 142-54. PMID: 26440581
- Effects of Ultrasound Treatment on Physiochemical Properties and Antimicrobial Activities of Whey Protein-Totarol Nanoparticles. | Ma, S., et al. 2017. J Food Prot. 80: 1657-1665. PMID: 28876131
- Antibacterial activity and mode of action of totarol against Staphylococcus aureus in carrot juice. | Shi, C., et al. 2018. J Food Sci Technol. 55: 924-934. PMID: 29487434
- Application of totarol as natural antibacterial coating on dental implants for prevention of peri-implantitis. | Xu, Z., et al. 2020. Mater Sci Eng C Mater Biol Appl. 110: 110701. PMID: 32204015
- Totarol, a natural diterpenoid, induces selective antitumor activity in SGC-7901 human gastric carcinoma cells by triggering apoptosis, cell cycle disruption and suppression of cancer cell migration. | Xu, T., et al. 2021. J BUON. 26: 640. PMID: 34077024
- Mode of antibacterial action of totarol, a diterpene from Podocarpus nagi. | Haraguchi, H., et al. 1996. Planta Med. 62: 122-5. PMID: 8657742
- Antibacterial activity of anacardic acid and totarol, alone and in combination with methicillin, against methicillin-resistant Staphylococcus aureus. | Muroi, H. and Kubo, I. 1996. J Appl Bacteriol. 80: 387-94. PMID: 8849640
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol, 100 mg | sc-226866 | 100 mg | $179.00 | |||
(4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol, 500 mg | sc-226866A | 500 mg | $714.00 | |||
(4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol, 1 g | sc-226866B | 1 g | $1295.00 | |||
(4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol, 2 g | sc-226866C | 2 g | $2040.00 |