3-Iodothyronamine Hydrochloride A metabolite of thyroid hormone

3-Iodothyronamine Hydrochloride  (CAS 788824-64-6)

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Synonym: 4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride
Application: A metabolite of thyroid hormone
CAS Number: 788824-64-6
Molecular Weight: 391.63
Molecular Formula: C14H15ClINO2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
3-Iodothyronamine Hydrochloride sc-209626 2.5 mg $280.00

3-Iodothyronamine Hydrochloride is a novel metabolite of thyroid hormone (TH). It is an endogenous and rapid-acting derivative of the thyroid hormone.


References

Davis, P., et al.: Thyroid, 6, 497 (1996), Falkenstein, E., et al.: Pharmacol. Rev., 52, 513 (2000), Yen, P., et al.: Physiol. Rev., 81, 1097 (2001), Pinna, G., et al.: Endocrinology, 143, 1789 (2002),

Physical State :
Solid
Solubility :
Soluble in DMSO, and methanol.
Storage :
Store at 4° C
Melting Point :
209-211° C
Boiling Point :
432.94° C at 760 mmHg (Predicted)
Density :
1.64 g/cm3 (Predicted)
Refractive Index :
n20D 1.67 (Predicted)
IC50 :
Trace amine-associated receptor 1: EC5050 = 22.4 nM (rat); Trace amine-associated receptor 1: EC5050 = 314 nM (mouse); Trace amine-associated receptor 1: EC5050 = 1.51 µM (human)
pK Values :
pKa: 9.95 (Predicted), pKb: 9.68 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 3077, Class 9, Packing group III
PubChem CID :
46781974
MDL Number :
MFCD11973726
SMILES :
C1=CC(=CC=C1O)OC2=C(C=C(C=C2)CCN)I.Cl

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Certificate of Analysis

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3-Iodothyronamine Hydrochloride Product Citations

See how others have used 3-Iodothyronamine Hydrochloride. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25706283
Dinter, J. et al. 2015. Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5. PloS one. 10: e0117774.

Citations 1 to 1 of 1 total

What is the solubility of this product?

Asked by: hawkeye11
Thank you for your question. 3-Iodothyronamine Hydrochloride, sc-209626, is soluble in both DMSO and Methanol, > 3 mg/mL.
Answered by: TechService7
Date published: 2016-12-15
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