25-Hydroxyvitamin D2

25-Hydroxyvitamin D2 (CAS 21343-40-8)

25-Hydroxyvitamin D2 | CAS 21343-40-8 is rated 5.0 out of 5 by 1.
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Synonym: 25-Hydroxyergocalciferol; 25-Hydroxycalciferol
Application: Biologically active vitamin D2 metabolite
CAS Number: 21343-40-8
Purity: ≥98%
Molecular Weight: 412.65
Molecular Formula: C28H44O2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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25-Hydroxyvitamin D2 is used in serum to measure the concentration of vitamin D produced by the skin. It is known that 25-Hydroxyvitamin D2 can be detected in human serum using high-performance liquid chromatography and ultraviolet detection. Vitamin D2, known as ergocalciferol, is a fat soluble secosteroid which regulates neuromuscular function, reduces inflammation and controls cell proliferation, differentiation and apoptosis. Furthermore, 25-Hydroxyvitamin D2 can be converted into calcitriol, which can act as a local cytokine.


References

1. Alvarez, J.C., et al. 2001. J. Chromatogr. B Biomed. Sci. Appl. 755: 129-135. PMID: 11393696

Physical State :
Solid
Storage :
Store at -20° C
Melting Point :
88.0-95.0° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 2811, Class 6.1, Packing group II
PubChem CID :
5710148
MDL Number :
MFCD02683431
SMILES :
C[C@H](/C=C/[C@H](C)C(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C

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Certificate of Analysis

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25-Hydroxyvitamin D2  Product Citations

See how others have used 25-Hydroxyvitamin D2. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26120794  Hawkes, CP. et al. 2015. J. Clin. Endocrinol. Metab. 100: 2883-9.

Citations 1 to 1 of 1 total

What is the shipping temperature for this product?

Asked by: hawkeye11
This chemical, 25-Hydroxyvitamin D2 (CAS 21343-40-8), ships ambient.
Answered by: Chemical Support 1
Date published: 2017-04-10

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. 25-Hydroxyvitamin D2 has an appearance of a white to off-white solid.
Answered by: Technical Support
Date published: 2017-02-23
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Rated 5 out of 5 by from Dabrowski et al Dabrowski et al. (PubMed ID 26035242) found that 25-Hydroxycalciferol led to lower production of granulocytes and macrophages colony stimulating factor, interleukin 6, Tumor Necrosis Factor, and an increase in mRNA expression for Cathelicidin Antimicrobial Peptide (CAP) in pregnant women. -SCBT Publication Review
Date published: 2015-04-21
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