2-Thiouridine A pyrimidine nucleoside which contains a reactive 2-thiocarbonyl group

2-Thiouridine (CAS 20235-78-3)

2-Thiouridine | CAS 20235-78-3 is rated 5.0 out of 5 by 1.
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Synonym: 1-β-D-Ribofuranosyl-2-thiouracil
Application: A pyrimidine nucleoside which contains a reactive 2-thiocarbonyl group
CAS Number: 20235-78-3
Molecular Weight: 260.27
Molecular Formula: C9H12N2O5S
* Refer to Certificate of Analysis for lot specific data (including water content).
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2-Thiouridine is a modified nucleotide, essential for normal cell growth in some bacterial species. This compound is also able to chelate several metal ions.

Physical State :
Solid
Solubility :
Soluble in DMSO, methanol, and water.
Storage :
Store at 4° C
Melting Point :
216-218° C (lit.)
Boiling Point :
539.41° C (Predicted)
Density :
~1.7 g/cm3 (Predicted)
Refractive Index :
n20D 1.73 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3036443
MDL Number :
MFCD03788697
SMILES :
C1=CN(C(=S)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

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Certificate of Analysis

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Rated 5 out of 5 by from Heuberger et al Heuberger et al. (PubMed ID 25654265) found that substituting uridine with 2-Thiouridine in RNA oligonucleotides improved the kinetics and fidelity of nonenzymatic primer RNA extension. -SCBT Publication Review
Date published: 2015-05-09
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