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2-Methyl-1-phenyl-2-propanol (CAS 100-86-7)

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Alternate Names:
Benzyl dimethyl carbinol; 1,1-Dimethyl-2-phenylethyl alcohol
CAS Number:
100-86-7
Molecular Weight:
150.22
Molecular Formula:
C10H14O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Methyl-1-phenyl-2-propanol, also known as α-methylbenzyl alcohol, is a compound widely utilized in various research fields for its diverse applications and unique chemical properties. One of the prominent uses of this chemical is as a chiral auxiliary in asymmetric synthesis, particularly in the preparation of enantiomerically pure compounds. Its chirality arises from the asymmetric carbon atom adjacent to the aromatic ring, which allows it to induce stereochemical control during certain chemical reactions, leading to the formation of specific enantiomers with high optical purity. Additionally, 2-Methyl-1-phenyl-2-propanol serves as a versatile building block in the synthesis of pharmaceutical intermediates, agrochemicals, and fine chemicals. Its ability to undergo various transformations, including oxidation, reduction, and functional group interconversion, makes it valuable in the design and development of new chemical entities with desired biological activities. Furthermore, this compound has found applications in the preparation of flavor and fragrance compounds, where its aromatic moiety contributes to the overall olfactory profile of the final product. In research, α-methylbenzyl alcohol continues to be explored for its potential as a key reagent in organic synthesis and as a precursor in the production of valuable compounds for industrial and academic purposes.


2-Methyl-1-phenyl-2-propanol (CAS 100-86-7) References

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  2. Parameters influencing the release of tertiary alcohols from the surface of 'spherical' dendrimers and 'linear' stylomers by neighbouring-group-assisted hydrolysis of 2-carbamoylbenzoates.  |  Trachsel, A., et al. 2009. Chemistry. 15: 2846-60. PMID: 19191231
  3. Characterization of anthraquinone-2-carbonyl chloride as an alcohol derivatization reagent for negative ion chemical ionization mass spectrometry.  |  Simpson, JT., et al. 1995. J Am Soc Mass Spectrom. 6: 148-51. PMID: 24222077
  4. Catalysis and molecular magnetism of dinuclear iron(III) complexes with N-(2-pyridylmethyl)-iminodiethanol/-ate.  |  Shin, JW., et al. 2014. Dalton Trans. 43: 3999-4008. PMID: 24452503
  5. Supramolecular Structure of Phenyl Derivatives of Butanol Isomers.  |  Grelska, J., et al. 2022. J Phys Chem B. 126: 3563-3571. PMID: 35522735
  6. The kinetics and mechanisms of gas phase elimination of primary, secondary, and tertiary 2‐hydroxyalkylbenzenes[J].  |  Chuchani G, Rotinov A, Dominguez R M. 1999,. International journal of chemical kinetics,. 31(6):: 401-407.
  7. Transfer hydrogenolysis of aromatic alcohols using Raney catalysts and 2-propanol[J].  |  Gross B H, Mebane R C, Armstrong D L. 2001,. Applied Catalysis A: General,. 219(1-2):: 281-289.
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Methyl-1-phenyl-2-propanol, 100 g

sc-223448
100 g
$35.00