1-Methyl-2-pyrrolidinone A pyrrolidinone compound

1-Methyl-2-pyrrolidinone (CAS 872-50-4)

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Synonym: N-Methylpyrrolid-2-one; NMP
Application: A pyrrolidinone compound
CAS Number: 872-50-4
Purity: ≥99%
Molecular Weight: 99.13
Molecular Formula: C5H9NO
* Refer to Certificate of Analysis for lot specific data (including water content).
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1-Methyl-2-pyrrolidinone is a pyrrolidinone compound solvent that has been documented to act a cosolvent and a complexing agent at the same time. The compound has been used in gel filtration of protected peptides, as well as utilized as a cryoprotective chemical for the freeze fracture technique.


References

1. Galpin, I.J. et al. 1976. J. Chromatogr. 123(1): 237-242. PMID: 950355
2. Sanghvi, R. et al. 2008. AAPS PharmSciTech. 9(2): 366-376. PMID: 18431671
3. Schiller, A. et al. 1978. Mikroskopie. 34(1-2): 19-13.

Physical State :
Liquid
Solubility :
Soluble in water (fully), chloroform, and methanol.
Storage :
Store at room temperature
Melting Point :
-24° C
Boiling Point :
81-82° C at 10 mmHg
Density :
1.03 g/mL at 25° C (lit.)
Refractive Index :
n20D 1.47 (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
UY5790000
PubChem CID :
13387
Merck Index :
14: 6117
MDL Number :
MFCD00003193
EC Number :
212-828-1
Beilstein Registry :
106420
SMILES :
CN1CCCC1=O

Download SDS (MSDS)

Certificate of Analysis

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