1-EBIO is the first activator of epithelial KCa channels identified. 1-EBIO stimulates a large and sustained trans-epithelial Cl- secretory response across T84 monolayers. Induces hyperpolarization to the same magnitude as ACh in aortic valve endothelial cells. 1-EBIO is an activator of CFTR, SK and Ik1.
1. Devor, D.C., et al. 1996. Am. J. Physiol. 271: L775-L784. PMID: 8944721 2. Adeagbo, A.S. 1999. Eur. J. Pharmacol. 379: 151-159. PMID: 10497901 3. Kusama, N., et al. 2005. Br. J. Pharmacol. 146: 487-497. PMID: 16056232
Soluble in ethanol (100 mM), DMSO (100 mM), and tris buffer solution (33 mM).
Store at room temperature
327.75° C (Predicted)
1.16 g/cm3 (Predicted)
n20D 1.57 (Predicted)
Single ptotein: Ki= >50 µM (rat)
pKa: 12.29 (Predicted), pKb: 0.51 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Download SDS (MSDS)
Certificate of Analysis
Adobe Acrobat Reader is required to reliably view, print and comment on PDF documents
See how others have used 1-EBIO. Click on the entry to view the PubMed entry
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.