Photoreactive Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Photoreactive Crosslinkers. Photoreactive Crosslinkers may be activated by UV light to indiscriminately bind nearly any nearby functionality. Typically one end of a photoreactive crosslinker is amine or sulfhydryl reactive as to bind a known target, and the other end is a photoreactive group, which upon activation with UV light forms a highly reactive intermediate. There are many different photoreactive groups that have found use in crosslinking applications. Benzophenone, aryl azides, and diazirine are all commonly employed. Aryl azides may be modified with a nitro group in order to increase the wavelenght of UV absorption, flouro groups to promote nitrene formation rather than a ring expansion upon irradiation, and hydroxyl groups to allow the aromatic substitution of iodine-125 for radiolabeling purposes. Diazirine based crosslinkers are particularly desirable for their increased photostability while still easily and efficiently activated by long-wave UV light (330-370 nm).

Produkt/Anwendungen CAS Katalog # Menge Preis Referenzen Bewertung
N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate
A fluorinated, aryl azide-based, amine- and photoreactive crosslinker
126695-58-7 sc-208056
50 mg
$240.00
0
2-[2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid Methyl Ester
A cross-linking reagent
165963-73-5 sc-208970
5 mg
$280.00
0
3-(Benzophenone-4-carboxamido)-2-maleimidopropanoic acid
A maleimide derivative
887352-68-3 sc-209472
5 mg
$280.00
0
4-(Maleimido)benzophenone
A benzophenone-based, sulfhydryl-reactive photoreactive crosslinker
92944-71-3 sc-209847
100 mg
$142.00
0
4-(N-Succinimidylcarboxy)benzophenone
A benzophenone-based, amine- and photoreactive crosslinker
91990-88-4 sc-209864
25 mg
$220.00
0
4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid
A photoreactive aromatic diazirine
85559-46-2 sc-209896
5 mg
$280.00
0
4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester
A photoaffinity label and crosslinking reagent
87736-89-8 sc-209897
2.5 mg
$250.00
0
4-Azido-2,3,5,6-tetrafluorobenzoic Acid
A fluorinated aryl azide photo cross linker
122590-77-6 sc-209954
100 mg
$280.00
0
p-Azidophenacyl Bromide
An aryl azide-based, sulfhydryl- and photoreactive crosslinker
57018-46-9 sc-212500
1 g
$260.00
0
S-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine
A radioionatable, cleavable, photoactivable cross linking agent
164575-82-0 sc-212808
10 mg
$280.00
0
S-[2-(Iodo-4-Azidosalicylamido)ethylthio]-2-thiopyridine
175093-14-8 sc-212809
5 mg
$280.00
0
2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6 -biotinamidocaproyl)-L-lysinyl]ethyl 2-Carboxyethyl Disulfide
sc-213714
1 mg
$250.00
0
2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]ethyl Methanethiosulfonate
A biotin containing suflhydryl- and photo-reactive crosslinker
1356383-18-0 sc-213715
1 mg
$300.00
0
2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6 -aminocaproyl]-N6-(6-biotinamidocaproyl)-L -lysinylamido}] Ethyl 2-Carboxyethyl Disulfide
sc-213718
1 mg
$280.00
0
2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6 -aminocaproyl]-N6-(6-biotinamidocaproyl)-L-lysinylamido}] Ethyl 2-(N-Sulfosuccinimydylcarboxy)ethyl Disulfide, Sodium Salt
A biotin label transfer reagent
sc-213719
1 mg
$350.00
0
2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6- aminocaproyl]-N6-(6-biotinamidocaproyl)-L -lysinylamido}ethyl Methanethiosulfonate
A biotin containing sulfhydryl- and photo-reactive crosslinker
1356841-34-3 sc-213720
1 mg
$250.00
0
Benzophenone-4-isothiocyanate
A benzophenone-based, hydroxyl- and photoreactive crosslinker
26328-59-6 sc-214587
100 mg
$183.00
1
Benzophenone-4-carboxamidocysteine Methanethiosulfonate
A trifunctional conjugate containing a photo reactive benzophenone group and an MTS function for SH coupling
317821-69-5 sc-217724
10 mg
$280.00
0
N-Succinimidyl 4-Azidosalicylate
A hydroxyl-containing, photoreactive aryl azide-based crosslinker for 125I radiolabeling
96602-46-9 sc-219224
50 mg
$300.00
0
SASD
A hydroxyl-containing, aryl azide-based, amine- and photoreactive crosslinker, 18.9 angstrom spacer arm
144650-95-3 sc-220093
10 mg
$250.00
0
2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6 -biotinamidocaproyl)-L-lysinyl]ethyl 2'- (N-sulfosuccinimidylcarboxy)ethyl disulfide, sodium salt
A biotin derivative cross-linking reagent
sc-223337
1 mg
$300.00
0
Bis[2-(4-azidosalicylamido)ethyl] disulfide
A homobifunctional, long chain cross-linking reagent
199804-21-2 sc-239377
10 mg
$265.00
0
5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester
A nitrate-containing, aryl azide-based, amine- and photoreactive crosslinker
60117-35-3 sc-256884
100 mg
$222.00
0
6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester
A photoactive, heterobifunctional cross-linking reagent
64309-05-3 sc-256960
50 mg
$516.00
0
N-Hydroxysuccinimidyl-4-azidobenzoate
An aryl azide-based, amine- and photoreactive crosslinker
53053-08-0 sc-263835
100 mg
$100.00
0
Sulphosuccinimidyl 6-(4'-azido-2'-nitrophenylamino)hexanoate
A nitrate-containing, aryl azide-based, amine- and photoreactive crosslinker
102568-43-4 sc-355990
100 mg
$300.00
0
SDA (NHS-Diazirine)
A NHS-diazirine based photoreactive crosslinker. Membrane permeable and cleavable with a 3.9 Angstrom spacer arm.
sc-397278
50 mg
$345.00
0
LC-SDA (NHS-LC-Diazirine)
An NHS-diazirine based photoreactive crosslinker
sc-397279
50 mg
$465.00
0
SDAD (NHS-SS-Diazirine)
An NHS-diazirine based photoreactive crosslinker. Membrane permeable and cleavable with a 13.5 Angstrom spacer arm.
sc-397280
50 mg
$465.00
0
Sulfo-SDA (Sulfo-NHS-Diazirine)
A sulfo-NHS-diazirine based photoreactive crosslinker. Membrane impermeable with a 3.9 Angstrom spacer arm.
sc-397281
50 mg
$465.00
0
Sulfo-LC-SDA (Sulfo-NHS-LC-Diazirine)
A sulfo-NHS-diazirine based photoreactive crosslinker. Membrane impermeable with a 12.5 Angstrom spacer arm.
sc-397283
50 mg
$465.00
0
Sulfo-SDAD (Sulfo-NHS-SS-Diazirine)
A sulfo-NHS-diazirine based photoreactive crosslinker. Membrane impermeable and cleavable with a 13.5 Angstrom spacer arm.
sc-397284
50 mg
$465.00
0
L-Photo-Leucine
A photoreactive amino acid analog used for protein-protein interaction studies in live cells
sc-397286
100 mg
$700.00
0
L-Photo-Methionine
A photoreactive amino acid analog used for protein-protein interaction studies in live cells
sc-397287
100 mg
$465.00
0

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