Santa Cruz Biotechnology offers a variety of gene silencing products to target synthesis and degradation proteins via RNA interference (RNAi). Proteolytic degradation is essential for normal cell cycle progression, cellular differentiation and stress responses. Degradation proteins are necessary to catalyze the breakdown of the extracellular matrix during processes such as embryonic development, reproduction, tissue remodeling, arthritis and metastasis. Synthesis and degradation proteins also play a necessary role in the activation of apoptosis pathways. To knockdown expression of synthesis and degradation proteins, Santa Cruz Biotechnology offers siRNA, shRNA plasmid and shRNA lentiviral particles.