Sodium Channel Modulators

Santa Cruz Biotechnology now offers a broad range of Sodium Channel Modulators. Sodium Channel Modulators are agents that either block, activate, or modify sodium ion channels. They are used in neurobiology and have implications in pharmacology. Our popular products such as QX 314 chloride, 5-(N-Ethyl-N-isopropyl)-Amiloride, and Amiloride, 5-(N,N-Dimethyl)-, hydrochloride are typically available for immediate shipment.

indicates a highly recommended product based on customer preference.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
QX 314 chloride
A voltage-activated Na+ channel blocker
5369-03-9 sc-203674
50 mg
$125.00
0
5-(N-Ethyl-N-isopropyl)-Amiloride
A selective Na+/H+ antiporter inhibitor
1154-25-2 sc-202458
5 mg
$55.00
6
Daidzein
An inactive analog of genistein, a tyrosine kinase inhibitor and an estrogen receptor activator
486-66-8 sc-24001
sc-24001A
sc-24001B
100 mg
500 mg
5 g
$20.00
$30.00
$100.00
11
Amiloride, 5-(N,N-Dimethyl)-, hydrochloride
An Na+-H+ exchanger inhibitor
2235-97-4 sc-202459
5 mg
$50.00
5
QX-314
A sodium channel protein inhibitor
21306-56-9 sc-3579
100 mg
$66.00
12
Amiloride hydrochloride dihydrate
An epithelial sodium channel blocker
17440-83-4 sc-364401
200 mg
$75.00
1
KR-32568
A sodium/H2 exchanger-1 (NHE-1) inhibitor
852146-73-7 sc-252934
5 mg
$157.00
0
Batrachotoxin
A neurotoxic voltage-gated Na+ channel activator
23509-16-2 sc-201086
10 µg
$250.00
0
Riluzole
A sodium channel protein inhibitor
1744-22-5 sc-201081
sc-201081A
sc-201081B
sc-201081C
20 mg
100 mg
1 g
25 g
$15.00
$180.00
$200.00
$300.00
0
Monensin Sodium Salt
A monovalent cation ionophore and transporter
22373-78-0 sc-200109
1 g
$68.00
1
5,5-Diphenyl Hydantoin
A sodium channel protein inhibitor
57-41-0 sc-210385
5 g
$30.00
0
Procaine
A sodium channel blocker and inhibitor of a variety of processes
59-46-1 sc-296134
sc-296134A
25 g
50 g
$101.00
$180.00
0
Procainamide hydrochloride
A Na+ channel blocker and Dnmt inhibitor
614-39-1 sc-202297
10 g
$36.00
0
Amiloride
2609-46-3 sc-337527
1 g
$225.00
4
Benzamil dot HCl
A potent blocker of sodium channels and Ca2+ transients
2898-76-2 sc-201070
50 mg
$195.00
1
Benzamil hydrochloride
A potent blocker of Na+H+ and Na+Ca+
161804-20-2 sc-252410
10 mg
$69.00
0
Diphenhydramine hydrochloride
A histamine H1-receptor antagonist
147-24-0 sc-204729
sc-204729A
sc-204729B
10 g
25 g
100 g
$50.00
$80.00
$0.00
0
Penicillin G procaine
A combination of Penicillin G and Procaine
6130-64-9 sc-205797
sc-205797A
10 g
25 g
$34.00
$36.00
0
Disopyramide
An antiarrhythmic (class IA) and a sodium channel blocker
3737-09-5 sc-207585
100 mg
$250.00
0
Lidocaine hydrochloride monohydrate
A fast voltage-gated sodium channel blocker
6108-05-0 sc-202211
5 g
$31.00
0
Disopyramide phosphate salt
A sodium channel blocker
22059-60-5 sc-252757
1 g
$220.00
0
Halofantrine hydrochloride
An inhibitor of the hERG channel
36167-63-2 sc-255195
10 mg
$118.00
0
Bupivacaine Free Base
Local anesthetic which binds to the intracellular portion of sodium channels and blocks sodium influx into the nerve cells
38396-39-3 sc-204657
sc-204657A
sc-204657B
sc-204657C
1 g
5 g
25 g
100 g
$103.00
$235.00
$800.00
$3,000.00
0
Flecainide
An antiarrhythmic RyR-2 inhibitor
54143-55-4 sc-219833
100 mg
$280.00
0
Aconitine
A lipid-soluble and potent neurotoxin that activates voltage gated sodium channels
302-27-2 sc-202441
sc-202441A
sc-202441B
sc-202441C
25 mg
250 mg
500 mg
1 g
$31.00
$250.00
$385.00
$750.00
0
Mepivacaine hydrochloride
An anesthetic
1722-62-9 sc-252996
1 g
$132.00
0
Mexiletine hydrochloride
A sodium channel blocker
5370-01-4 sc-253048
25 g
$82.00
0
SDZ-201106 (+)
97730-95-5 (racemic) sc-222302
5 mg
$59.00
0
BIA 2-093
A voltage-gated sodium channel blocker
236395-14-5 sc-252432
10 mg
$162.00
0
Veratridine
A voltage dependent Na+ channel opening agent
71-62-5 sc-201075
sc-201075A
10 mg
50 mg
$89.00
$355.00
0
Benzocaine
A surface anesthetic
94-09-7 sc-239305
100 g
$28.00
0
Lidocaine
A selective inverse peripheral histamine H1-receptor agonist
137-58-6 sc-204056
sc-204056A
50 mg
1 g
$49.00
$125.00
0
Triamterene
An Na+ channel blocker
396-01-0 sc-213103
5 g
$35.00
0
Kavain (+/-)
A biologically active component of kava that blocks various cationic voltage-gated channels
500-64-1 sc-201077
sc-201077A
50 mg
250 mg
$64.00
$194.00
1
5,5-Diphenylhydantoin sodium salt
A sodium channel protein inhibitor
630-93-3 sc-214337
sc-214337A
25 g
100 g
$42.00
$93.00
0
Dihydroouabain
1183-35-3 sc-252720
50 mg
$304.00
0
5-(N,N-Hexamethylene)amiloride
An inhibitor of Na+/H+ antiport
1428-95-1 sc-239021
25 mg
$85.00
0
Mexiletine hydrochloride
A use dependent blocker of sodium channels
5370-01-4 sc-203633
50 mg
$75.00
0
Proxymetacaine Hydrochloride
A sodium channel protein inhibitor
5875-06-9 sc-205820
sc-205820A
100 mg
250 mg
$78.00
$164.00
0
Quinidine sulfate dihydrate
A Na+ channel blocker
6591-63-5 sc-205967
5 g
$60.00
0
Bupivacaine hydrochloride
A Na+ channel blocker
18010-40-7 sc-252524
sc-252524A
1 g
5 g
$63.00
$106.00
0
QX 222
A Na+ channel blocker
21236-55-5 sc-203673
sc-203673A
10 mg
50 mg
$49.00
$225.00
0
Ambroxol hydrochloride
An expectorant antioxidant and antiinflammatory agent
23828-92-4 sc-200816
1 g
$53.00
0
Icilin
A potent agonist of the TRPM8 and ENaCδ ion channels
36945-98-9 sc-201557
sc-201557A
10 mg
50 mg
$81.00
$240.00
2
Vinpocetine
An inhibitor of Ca2+/CaM-PDE with neuroprotective properties
42971-09-5 sc-201204
sc-201204A
20 mg
100 mg
$55.00
$214.00
2
Deltamethrin
A Type II pyrethroid insecticide that potently inhibits calcineurin
52918-63-5 sc-24013
sc-24013A
10 mg
50 mg
$62.00
$259.00
9
Flecainide acetate
A cadiac Na+ channel blocker
54143-56-5 sc-203581
sc-203581A
10 mg
50 mg
$59.00
$205.00
0
Encainide hydrochloride
CAS: 66794-74-9, MF: C22H28N2O2•HCl, MW: 388.93, Purity: ≥98%
66794-74-9 sc-252774
10 mg
$156.00
0
Tocainide hydrochloride
A sodium channel blocker that may be used in cell signaling studies
71395-14-7 sc-253706
10 mg
$128.00
0
Lamotrigine
A sodium channel protein inhibitor
84057-84-1 sc-201079
sc-201079A
10 mg
50 mg
$111.00
$462.00
1
5-(N-Methyl-N-isobutyl)-Amiloride
An NHE inhibitor
96861-65-3 sc-202929
sc-202929A
5 mg
25 mg
$80.00
$185.00
0
SDZ-201106 (+/-), (DPI-201106)
A positive inotropic and calcium sensitizing agent
97730-95-5 sc-201072
sc-201072A
25 mg
100 mg
$45.00
$192.00
1
Rufinamide
A sodium channel protein inhibitor
106308-44-5 sc-212794
10 mg
$116.00
0
Ibutilide Fumarate
A sodium channel protein inhibitor
122647-32-9 sc-211627
10 mg
$200.00
0
Sipatrigine
A glutamate release inhibitor and voltage-dependent sodium channel blocker
130800-90-7 sc-362796
sc-362796A
10 mg
50 mg
$185.00
$772.00
0
KC 12291 hydrochloride
An atypical voltage-gated sodium channel blocker
181936-98-1 sc-204028
sc-204028A
10 mg
50 mg
$175.00
$739.00
0
KB-R7943 MESYLATE
A potent and selective NCKX inhibitor
182004-65-5 sc-202681
10 mg
$149.00
1
Ralfinamide mesylate
A mixed sodium and calcium channel protein inhibitor
202825-45-4 sc-362788
sc-362788A
10 mg
50 mg
$84.00
$339.00
0
Butacaine Sulphate
149-15-5 sc-210971
1 g
$280.00
0
Lappaconitine hydrobromide
A selective TTX-sensitive Na+ channel blocker
97792-45-5 sc-300905
10 mg
$420.00
0
R(-)-Me5 hydriodide
MF: C13H21NO•HI, MW: 335.22
sc-301654
5 mg
$62.00
0
Allethrin
A synthetic compound that modulates sodium channels in the nerve cell membrane
584-79-2 sc-202921
sc-202921A
10 mg
25 mg
$30.00
$41.00
0
Phenamil methanesulfonate (free base)
An amiloride analog that irreversibly blocks amiloride-sensitive Na+ channels.
2038-35-9 sc-202280
5 mg
$98.00
0
Brevetoxin PbTx-2
A polyether neurotoxin and sodium influx inducer
79580-28-2 sc-203853
100 µg
$645.00
0
PD-85639
A potent and selective sodium channel blocker for anesthetic receptor
150034-24-5 sc-201084
sc-201084A
5 mg
25 mg
$77.00
$309.00
0
Co 102862
An inhibitor of voltage-gated Na+ channels
181144-66-1 sc-203900
sc-203900A
10 mg
50 mg
$94.00
$495.00
0
A 887826
A potent voltage-dependent blocker of the sodium channel NaV1.8
1266212-81-0 sc-362708
sc-362708A
10 mg
50 mg
$169.00
$712.00
0
trans-Permethrin solution
A synthetic, neurotoxic insecticidal compound
61949-77-7 sc-237224
2 ml
$76.00
0
DL-Kavain
3155-48-4 sc-234817
500 mg
$21.00
0
Bendroflumethiazide
A sodium reabsorption inhibitor in the DCT
73-48-3 sc-233928
1 g
$41.00
0
Tolperisone Hydrochloride
An ion channel blocker
3644-61-9 sc-208444
100 mg
$188.00
0
Valproic Acid
A branched chain fatty acid
99-66-1 sc-213144
10 g
$70.00
1
Benzocaine-d4
A labeled version of the anesthetic compound benzocaine
342611-08-9 sc-217722
2.5 mg
$250.00
0
Pentisomide
A sodium channel blocker
78833-03-1 sc-219569
2.5 mg
$350.00
0
Amiloride-15N3 Hydrochloride
A sodium channel blocker
1216796-18-7 sc-217623
5 mg
$3,000.00
0
Lamotrigine isethionate
A water soluble inhibitor of voltage gated sodium channels of presynaptic neurons
113170-86-8 sc-218654
10 mg
$220.00
0
NS8593 hydrochloride
A calcium channel modulator
875755-24-1 sc-253203
5 mg
$138.00
0

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