Gene Regulation Reagents

Santa Cruz Biotechnology now offers a broad range of Gene Regulation Reagents. Gene Regulation Reagents are compounds that affect the expression of genes and their products through a variety of mechanisms, including the up- or down- regulation of gene expression via the activation or inhibition of transcription factors. Our popular products such as Hypoxia Inducible Factor-1α Inhibitor, Mitomycin C, and Dimethyloxaloylglycine (DMOG) are typically available for immediate shipment.

indicates a highly recommended product based on customer preference.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Bufalin
Inducer of apoptosis in human HL-60 and U-937 cell lines
465-21-4 sc-200136
10 mg
$97.00
1
BAY 11-7082
An anti-inflammatory agent and NFκB inhibitor
19542-67-7 sc-200615
sc-200615A
sc-200615B
10 mg
50 mg
5 mg
$81.00
$342.00
$60.00
58
Dimethyloxaloylglycine (DMOG)
An inhibitor of PHF and FIH-1 that upregulates HIF-1α and FLRG
89464-63-1 sc-200755
sc-200755A
sc-200755B
10 mg
50 mg
100 mg
$70.00
$279.00
$0.00
6
Linoleic Acid
A fatty acid with cytotoxic activity that influences the inflammatory process
60-33-3 sc-200788
sc-200788A
100 mg
1 g
$23.00
$52.00
1
Procysteine
A precursor in glutathione synthesis
19771-63-2 sc-200811
1 g
$90.00
0
Actinomycin D
A potent antibiotic that binds to the GpC steps of DNA
50-76-0 sc-200906
sc-200906A
5 mg
25 mg
$62.00
$224.00
5
Chromomycin A3
A G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye
7059-24-7 sc-200907
10 mg
$206.00
0
Hoechst 33342 trihydrochloride
An A:T-specific DNA minor groove ligand used for visualizing cellular DNA
23491-52-3 sc-200908
100 mg
$131.00
2
Mithramycin A
A polymerase inhibitor that binds to GC rich sequences located in the minor groove of DNA
18378-89-7 sc-200909
1 mg
$53.00
2
Rifampicin
An antibiotic that potently inhibits RNA polymerase and is an activator of PXR
13292-46-1 sc-200910
sc-200910A
1 g
5 g
$83.00
$306.00
4
Lycorine hydrochloride
A protein synthesis inhibitor
2188-68-3 sc-200917
sc-200917A
10 mg
50 mg
$75.00
$299.00
0
Oleylethanolamide
An activator of Neu/ErbB2 receptors and a mediator of p38 and JNK kinases
111-58-0 sc-201400
sc-201400A
10 mg
50 mg
$55.00
$164.00
0
Berninamycin A
An antibiotic that contains sulfur and highly modified cyclic peptides
58798-97-3 sc-202077
sc-202077A
1 mg
5 mg
$250.00
$1,014.00
0
Blasticidin A
An aflatoxin production inhibitor
100513-53-9 sc-202082
1 mg
$500.00
0
(+)-cis,trans-Abscisic acid
A natural and active isomer of the abscission accelerating plant hormone.
21293-29-8 sc-202103
sc-202103A
500 µg
1 mg
$98.00
$179.00
0
Geninthiocin
A thiopeptide antibiotic tipA gene activator
158792-27-9 sc-202167
500 µg
$359.00
1
Leptomycin B, Free Acid
A potent nuclear export and RNA translation inhibitor
87081-35-4 sc-202210
sc-202210A
100 µg
500 µg
$128.00
$375.00
10
Pioglitazone
A PPAR agonist with potential antidiabetic characteristics
111025-46-8 sc-202289
sc-202289A
1 mg
5 mg
$48.00
$116.00
6
5-Aza-2prime-Deoxycytidine
A Dnmt inhibitor shown to alter gene expression
2353-33-5 sc-202424
25 mg
$200.00
1
5prime-Deoxy-5prime-methylthioadenosine
An endogenous methylthioadenosine phosphorylase substrate and potent inhibitor of PDE
2457-80-9 sc-202427
50 mg
$89.00
0
8-Chloroadenosine 3prime,5prime-Cyclic Monophosphate sodium salt
A cAMP analog with high selectivity for PKA I
41941-56-4 sc-202437
sc-202437A
1 mg
5 mg
$23.00
$92.00
0
B2
A cell permeable inhibitor of SIRT2 (sirtuin 2)
115687-05-3 sc-202486
sc-202486A
500 µg
5 mg
$30.00
$102.00
0
BADGE
An inhibitor of PPARγ and suppressor of TNFα
1675-54-3 sc-202487
25 g
$32.00
1
Bisbenzimide H 33258 Fluorochrome, Trihydrochloride
An A-T specific highly fluorescent DNA stain that has many uses
23491-45-4 sc-202503
sc-202503A
100 mg
250 mg
$72.00
$251.00
5
Dihydromyristicin
An inducer of glutathione S-transferase
52811-28-6 sc-202580
100 mg
$142.00
0
GW 1929
A potent, tyrosine-based PPARγ
196808-24-9 sc-202640
1 mg
$87.00
0
Histone Lysine Methyltransferase Inhibitor
An HMTase inhibitor known as BIX-01294 Trihydrochloride
935693-62-2 (hydrate) sc-202651
5 mg
$145.00
1
Levofloxacin hydrochloride
A fluoroquinolone antibiotic inhibitor of DNA gyrase and topoisomerase IV
177325-13-2 sc-202693
sc-202693A
1 g
5 g
$33.00
$77.00
1
O6-Benzylguanine
An effective substrate and efficient inactivator of DNA alkyltransferase
19916-73-5 sc-202747
sc-202747A
10 mg
50 mg
$44.00
$71.00
0
Rosiglitazone
A potent and selective PPARγ agonist
122320-73-4 sc-202795
sc-202795A
25 mg
100 mg
$106.00
$304.00
17
Smoothened Agonist, HCl
An Hh pathway agonist that interacts with the heptahelical domain of Smo
364590-63-6 sc-202814
sc-202814A
1 mg
5 mg
$200.00
$500.00
22
beta-Amanitin
A specific and potent inhibitor of eukaryotic RNA polymerase II and a mild inhibitor of RNA polymerase III
21150-22-1 sc-202860
1 mg
$195.00
0
M 344
A potent HDAC inhibitor with IC50 of 100 nM
251456-60-7 sc-203124
sc-203124A
1 mg
5 mg
$99.00
$304.00
8
EGFR Inhibitor
A highly selective, cell-permeable EGFR inhibitor
879127-07-8 sc-203934
1 mg
$99.00
0
RG 108
A Dnmt inhibitor that silences tumor suppressor genes
48208-26-0 sc-204235
sc-204235A
10 mg
50 mg
$125.00
$495.00
0
SID 7969543
A selective SF-1 inhibitor
868224-64-0 sc-204278
sc-204278A
10 mg
50 mg
$120.00
$510.00
0
alpha-Sarcin
A ribosome-inactivating protein and apoptosis inducer
86243-64-3 sc-204427
1 mg
$300.00
0
beta-Rubromycin
A quinone antibiotic agent that inhibits reverse transcriptase
27267-70-5 sc-204636
sc-204636A
1 mg
5 mg
$177.00
$712.00
0
Betamethasone
A glucocorticoid that induces gene expression and apoptosis
378-44-9 sc-204647
sc-204647A
100 mg
500 mg
$160.00
$555.00
0
N-tridecanoyl-L-Homserine lactone
A bacteria-produced lactone involved in quorum sensing
878627-21-5 sc-204812
sc-204812A
5 mg
10 mg
$39.00
$101.00
0
NFkappaB Activation Inhibitor III
A TNF-α-stimulated NF kappa B activation inhibitor
380623-76-7 sc-204818
5 mg
$99.00
2
13(S)-HODE-d4
Intended for use as an internal quantification standard
139408-39-2 sc-205006
sc-205006A
25 µg
100 µg
$112.00
$405.00
0
AG-041R
A potent gastrin/CCKB receptor antagonist that exhibits selective binding for CCKB compared to CCKA
199800-49-2 sc-205202
sc-205202A
1 mg
5 mg
$72.00
$325.00
0
Hypoxia inducible factor-1alpha Inhibitor
An HIF and HIF-1α inhibitor which suppresses expression of downstream target genes
934593-90-5 sc-205346
sc-205346A
sc-205346B
sc-205346C
1 mg
5 mg
10 mg
25 mg
$22.00
$100.00
$176.00
$385.00
12
Imipenem Monohydrate
A third generation cephalosporin and β-lactam antibiotic
64221-86-9 sc-205350
sc-205350A
25 mg
5 mg
$110.00
$55.00
1
LED209
A potent conserved membrane histidine sensor kinase
245342-14-7 sc-205368
sc-205368A
1 mg
5 mg
$18.00
$75.00
0
N-(beta-ketocaproyl)-L-Homoserine lactone
A component of quorum regulatory sensing
143537-62-6 sc-205396
sc-205396A
5 mg
25 mg
$46.00
$156.00
0
N-3-oxo-dodecanoyl-L-Homoserine lactone
An activator of transcription factors NF-κB and AP-2
168982-69-2 sc-205399
sc-205399A
1 mg
5 mg
$31.00
$139.00
0
N-3-oxo-octanoyl-L-Homoserine lactone
A reagent that promotes the expression of the transcriptional activator
147795-39-9 sc-205400
sc-205400A
5 mg
10 mg
$46.00
$88.00
0
N-3-oxo-tetradec-7Z-enoyl-L-Homoserine lactone
An antimicrobial agent that inhibits biofilm formation
482598-46-9 sc-205401
sc-205401A
1 mg
5 mg
$28.00
$126.00
0
N-butyryl-L-Homoserine lactone
A diffusable quorum sensing lactone
67605-85-0 sc-205402
sc-205402A
5 mg
10 mg
$28.00
$54.00
0
N-hexanoyl-L-Homoserine lactone
A small diffusible signaling molecule
147852-83-3 sc-205405
sc-205405A
sc-205405B
sc-205405C
5 mg
10 mg
25 mg
50 mg
$50.00
$76.00
$162.00
$276.00
1
13-cis-Retinoic acid
A vitamin A analog that inhibits cell proliferation
4759-48-2 sc-205568
sc-205568A
100 mg
250 mg
$67.00
$110.00
7
9-cis-Retinoic acid
A Cox-2 inhibitor that prevents cell proliferation and induces cell differentiation
5300-03-8 sc-205589
sc-205589A
sc-205589B
1 mg
5 mg
25 mg
$64.00
$135.00
$400.00
2
AG 1024
Inhibits insulin-stimulated cellular proliferation and IGF-1R autophosphorylation
65678-07-1 sc-205907
1 mg
$74.00
13
N-(Ketocaproyl)-L-homoserine Lactone
An autoinducer of P. fischeri luciferase
143537-62-6 sc-207922
100 mg
$213.00
0
Strontium Ranelate
A bone metabolism modulator
135459-87-9 sc-208403
10 mg
$280.00
0
SAG
A potent agonist of Hedgehog (Hh) signalling
912545-86-9 sc-212905
sc-212905A
1 mg
5 mg
$150.00
$395.00
12
10074-G5
An inhibitor of c-Myc-Max interaction
413611-93-5 sc-213578
sc-213578A
5 mg
25 mg
$82.00
$330.00
0
CB 1954
A compound for gene therapyt resrearch
21919-05-1 sc-214672
50 mg
$215.00
1
3,5-Diiodo-L-thyronine
An iodinated thyronine hormone that regulates activity
1041-01-6 sc-216601
sc-216601A
sc-216601B
sc-216601C
1 g
5 g
10 g
25 g
$220.00
$500.00
$902.00
$1,353.00
0
5-Fluoroorotic acid monohydrate
A gene regulation reagent for proteomics research
220141-70-8 sc-217188
1 g
$75.00
0
5-Azacytidine
A potent growth and Dnmt inhibitor
320-67-2 sc-221003
500 mg
$190.00
2
7-Aminoactinomycin D
A fluorescent DNA dye for apoptosis and flow cytomtery studies
7240-37-1 sc-221210
sc-221210A
1 mg
5 mg
$167.00
$390.00
7
BML-210
An inhibitor of HDAC activity and gene expression modulator
537034-17-6 sc-221369
sc-221369A
1 mg
5 mg
$77.00
$263.00
0
BML-266
A SIRT2 inhibitor
96969-83-4 sc-221371
sc-221371A
10 mg
50 mg
$102.00
$402.00
0
DIF-1
A cell growth suppressor that promotes differentiation in HL-60 cells
111050-72-7 sc-221541
sc-221541A
100 µg
500 µg
$64.00
$255.00
0
LXRalpha/beta Agonist
A specific liver X receptor (LXR) dual agonist
264206-85-1 sc-221864
10 mg
$315.00
0
N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone
An autoinducer
479050-91-4 sc-221977
sc-221977A
1 mg
5 mg
$47.00
$156.00
0
N-butyryl-L-Homocysteine thiolactone
A small signaling molecule involved in quorum sensing
202284-85-3 sc-221995
sc-221995A
5 mg
10 mg
$39.00
$101.00
0
N-decanoyl-L-Homoserine lactone
A small signaling molecule involved in quorum sensing
177315-87-6 sc-222001
sc-222001A
5 mg
10 mg
$60.00
$114.00
0
N-octanoyl-L-Homoserine lactone
A small signaling molecule involved in quorum sensing
147852-84-4 sc-222011
sc-222011A
5 mg
10 mg
$60.00
$89.00
0
Neurodazine
An inducer of neurogenesis of non-pluripotent C2C12 myoblasts
937807-66-4 sc-222056
10 mg
$145.00
0
RNA Polymerase III Inhibitor
An indazolo-sulfonamide compound displaying inhibitory activity against RNA Polymerase III
577784-91-9 sc-222257
10 mg
$390.00
0
Thyroid Hormone Receptor Antagonist, 1-850
A selective and high-affinity thyroid hormone receptor (TR) antagonist
251310-57-3 sc-222357
5 mg
$194.00
1
Toxin A from Clostridium difficile
A high molecular weight, small molecule GTPase inhibitor
sc-222361
sc-222361A
2 µg
100 µg
$192.00
$772.00
0
GW 3965 hydrochloride
A liver X receptor (LXR) activator
405911-17-3 sc-224011
sc-224011A
5 mg
25 mg
$134.00
$465.00
0
N-nonanoyl-L-Homoserine lactone
A rare odd-numbered acyl carbon chain produced by the wild-type Erwinia carotovora strain
177158-21-3 sc-224145
sc-224145A
5 mg
10 mg
$39.00
$74.00
0
4-(3,4-Dimethoxyphenyl)butyric acid
Has effects on apoptosis, proliferation and HDAC activity
13575-74-1 sc-226371
5 g
$54.00
0
L-Ascorbic acid 2-phosphate sesquimagnesium salt
A compound used in biocatalytic dephosphorylation, cell differentiation, and tissue engineering research
113170-55-1 sc-228390
sc-228390A
sc-228390B
sc-228390C
5 g
25 g
100 g
500 g
$57.00
$240.00
$500.00
$880.00
1
2-Benzylaminoethanol
Used in the synthesis of imidazoles as potent calcitonin antagonists
104-63-2 sc-229954
100 g
$27.00
0
2-Phospho-L-ascorbic acid trisodium salt
A long-lasting vitamin C derivative used in studies of gene repression
66170-10-3 sc-230644
sc-230644A
10 g
25 g
$61.00
$150.00
0
Dimethyl fumarate
An ester used for research purposes
624-49-7 sc-239774
25 g
$26.00
1
2-Bromohexadecanoic acid
A PPARδ agonist
18263-25-7 sc-251714
10 g
$38.00
1
Phytic acid dipotassium salt
A potent chelator of divalent and trivalent cations
129832-03-7 sc-253276
5 g
$215.00
0
5,6-Dichloropyridine-3-methanol
A novel CXCR3 (CXC chemokine receptor) inhibitor
54127-30-9 sc-278346
200 mg
$90.00
0
Hygromycin B solution
An antibiotic often used for selection of cells transfected with E. coli hygromycin resistance gene.
31282-04-9 sc-29067
1 g
$95.00
17
Fmoc-L-Lys(Me2)-OH*HCl
A Lysine derivative used to study histone modification
252049-10-8 sc-294919
100 mg
$300.00
0
Rifampin, gamma irradiated
13292-46-1 sc-296271
150 mg
$43.00
0
A1120
sc-300151
25 mg
$313.00
0
AMI-1, free acid
A chemical shown to inhibit arginine, in vitro, with no inhibitory effect on lysine
134-47-4 sc-300192
1 g
$96.00
0
GW6471
A complete inhibitor of PPARα that allows interaction with co-repressors
436159-64-7 sc-300779
5 mg
$203.00
1
Lys-Tyr-Lys acetate salt
CAS: 35193-18-1, MF: C21H35N5O5•xC2H4O2, MW: 437.53 (free base), Purity: ≥97%
35193-18-1 sc-300944
50 mg
$104.00
0
RETRA
CAS: 1036069-26-7, MF: C11H12ClNO3S2, MW: 305.80, Purity: ≥98%
1036069-26-7 sc-311522
5 mg
$115.00
0
BePl
A biochemical which selectively intercalates into triple-helical DNA
sc-319856
1 mg
$61.00
0
Mitomycin C
A DNA crosslinking agent that inhibits DNA synthesis, induces apoptosis in a variety of cells, and activates caspase
50-07-7 sc-3514
sc-3514A
sc-3514B
5 mg
2 mg
10 mg
$87.00
$50.00
$125.00
27
3-Deazaneplanocin, HCl salt
An effective S-adenosylhomocysteine hydrolase inhibitor
120964-45-6 sc-351856
sc-351856A
sc-351856B
1 mg
5 mg
10 mg
$150.00
$400.00
$700.00
2
tert-butyl 2-aminophenylcarbamate
An intermediate in the synthesis of histone deacetylase agents and antitumor agents
146651-75-4 sc-356014
sc-356014A
250 mg
1 g
$188.00
$380.00
0
Leptomycin B
A potent and specific nuclear export inhibitor that acts as an antifungal agent
87081-35-4 sc-358688
sc-358688A
sc-358688B
50 µg
500 µg
2.5 mg
$98.00
$400.00
$1,200.00
10
Staurosporine Solution in Ethyl Acetate
An ATP-competitive protein kinase inhibitor
62996-74-1 sc-360258
100 µg
$92.00
4
LG 100754
An agonist of RXR:PPARγ that enhances ligand binding activity
180713-37-5 sc-361231
sc-361231A
10 mg
50 mg
$142.00
$825.00
0
MC 1568
A class II (IIa) HDAC inhibitor selective for HDAC4 and HDAC6
852475-26-4 sc-362767
sc-362767A
10 mg
50 mg
$175.00
$555.00
1
UNC 0224
A potent G9a histone lysine methyltransferase (HMTase) inhibitor
1197196-48-7 sc-362816
sc-362816A
10 mg
50 mg
$190.00
$800.00
0
AK-7
A deacetylase which targets α-tubulin, histone 4, forkhead transcription factors, and several other substrates it is also a selective SIRT2 inhibitor
420831-40-9 sc-364096
sc-364096A
5 mg
25 mg
$54.00
$221.00
0
Triphenyl Compound A
A pirin inhibitor
21306-65-0 sc-364144
sc-364144A
1 mg
5 mg
$47.00
$101.00
0
C646
A selective p300, CBP, histone H3 and H4 inhibitor
328968-36-1 sc-364452
sc-364452A
10 mg
50 mg
$199.00
$902.00
0
Pimelic Diphenylamide 106
An HDAC1, HDAC2, HDAC3, and HDAC8 inhibitor
937039-45-7 sc-364589
sc-364589A
1 mg
5 mg
$41.00
$74.00
0
VAHA
An inhibitor to HDAC with efficacy against Class I and II enzymes
106132-78-9 sc-364642
sc-364642A
5 mg
25 mg
$64.00
$341.00
0
GSK J1
A selective and potent inhibitor of JMJDE and UTX demethylases
1373422-53-7 sc-391113
sc-391113A
10 mg
50 mg
$185.00
$781.00
0
I-BET 151 Hydrochloride
A BET bromodomain (BRD) inhibitor
1300031-49-5 (non HCl Salt) sc-391115
10 mg
$410.00
1
Dodecanoyl-L-homoserine lactone
A modulator of cell communication and regulation
137173-46-7 sc-391777
5 mg
$47.00
0
1,2,3,4,5,6,7,8-Octahydro-naphthalene
A quorum sensing agent
493-03-8 sc-396633
sc-396633A
1 g
5 g
$100.00
$350.00
0
2-Heptyl-3-hydroxyl-4-quinolone
An intercellular signal
108985-27-9 sc-396649
25 mg
$153.00
0
CASIN
A Cdc42 GTPase inhibitor
425399-05-9 sc-397016
10 mg
$209.00
0
5-Carboxy-8-hydroxyquinoline
A histone demethylase JMJD inhibitor
5852-78-8 sc-397023
5 mg
$86.00
0
WDR5-0103
A small molecule inhibitor of WDR5
890190-22-4 sc-397024
5 mg
$72.00
0
Pyroxamide
An HDAC1 inhibitor
382180-17-8 sc-397030
5 mg
$79.00
0
Cardionogen 1
An inhibitor of Wnt/β-catenin-dependent transcription
577696-37-8 sc-397033
sc-397033A
5 mg
25 mg
$109.00
$399.00
0
OAC-1
An Oct-4 activator which increases mRNA expression of Oct-4, Sox-2, Nanog, and Tet1
300586-90-7 sc-397046
sc-397046A
5 mg
25 mg
$80.00
$339.00
0
UNC 926 hydrochloride
A methyl lysine reader domain inhibitor
1184136-10-4 sc-397061
10 mg
$159.00
0
(+/-)-JQ1
A selective BET inhibitor that inhibits Brd4
1268524-69-1 sc-472932
5 mg
$156.00
0

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.