GDP/GTP Binding Protein

Santa Cruz Biotechnology offers a variety of gene editing products to target GDP/GTP binding proteins using the CRISPR/Cas9 system. Guanosine triphosphate (GTP)/guanosine diphosphate (GDP)-binding proteins have a different conformation depending on whether they are bound to GTP or GDP. GTP usually stabilizes the active conformation of these proteins, and hydrolysis of the bound GTP to GDP + Pi usually causes the protein to become inactive. Reactivation occurs when the bound GDP is released in exchange for GTP. Heterotrimeric G-proteins, short for guanine nucleotide binding proteins, are a family of GTP-binding proteins that play a role in second messenger cascades. Members of the family of small GTP-binding proteins have a broad range of functions, most of which pertain to cell communication and signaling cascades. Examples of such important GTP/GDP proteins include Rac, Rho, Ras, Vav and C3G. To knockdown expression of GDP/GTP binding proteins, Santa Cruz Biotechnology offers target-specific CRISPR/Cas9 Knockout (KO) Plasmids and CRISPR Double Nickase Plasmids.To activate transcription of GDP/GTP binding protein genes, Santa Cruz Biotechnology offers target-specific CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems.

LEARN MORE ABOUT:
si/shRNA CRISPR
 

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.