GABA Metabolism and Transport

Santa Cruz Biotechnology now offers a broad range of GABA Metabolism and Transport products. γ-Aminobutyric acid, or GABA, is the main inhibitory neurotransmitter relied upon by the central nervous system of most mammals. Generally, binding of a receptor by GABA causes inhibition due to hyperpolarization, although the exact underlying processes vary amongst receptor types. There is also evidence that GABA first possesses excitatory functions during the neonatal stage, then becomes inhibitory during development and adulthood. During development, it helps regulate the growth and differentiation of progenitor cells, and it is also necessary for maintaining muscle tone. GABA activity at the synapse is terminated when the neurotransmitter is taken up by the presynaptic nerve and local glial cells, a process mediated by temperature- and ion-dependent membrane transport systems. GABA is conserved via the GABA shunt pathway, a closed-loop process which metabolizes glutamate to form GABA, then converts GABA back into its precursor. GABA Metabolism and Transport products are useful for studying these pathways and the effects these can have on multiple physiological systems. Our popular products such as (-)-Bicuculline methobromide and Riluzole are typically available for immediate shipment.

indicates a highly recommended product based on customer preference.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
(-)-Bicuculline methobromide
An N-methylated derivative of the GABAA antagonist bicuculline
73604-30-5 sc-200436
50 mg
$143.00
0
DHEA
A negative modulator of GABAA receptors
53-43-0 sc-202573
10 g
$101.00
0
Riluzole
A sodium channel protein inhibitor
1744-22-5 sc-201081
sc-201081A
sc-201081B
sc-201081C
20 mg
100 mg
1 g
25 g
$15.00
$180.00
$200.00
$300.00
0
Etomidate
A GABAA receptors agonist
33125-97-2 sc-203577
10 mg
$122.00
0
NNC 711
A potent and selective inhibitor of GABA T-1
145645-62-1 sc-204132
sc-204132A
5 mg
25 mg
$116.00
$301.00
0
CGP 54626 hydrochloride
A potent and selective GABA b receptor antagonist
149184-21-4 sc-361142
sc-361142A
10 mg
50 mg
$195.00
$760.00
0
Flumazenil (Ro 15-1788)
A benzodiazepine antagonist
78755-81-4 sc-200161
sc-200161A
20 mg
100 mg
$62.00
$259.00
10
(+/-)-Baclofen
A selective agonist of the GABAB receptor
1134-47-0 sc-200464
sc-200464A
1 g
5 g
$49.00
$243.00
0
GS 39783
A positive modulator at GABAB receptors
39069-52-8 sc-203589
sc-203589A
10 mg
50 mg
$101.00
$575.00
0
SR 95531 Hydrobromide
A selective GABAA receptor antagonist
104104-50-9 sc-203701
sc-203701A
10 mg
50 mg
$145.00
$490.00
0
(+)-Bicuculline
A GABA A receptor antagonist
485-49-4 sc-202498
sc-202498A
50 mg
250 mg
$54.00
$201.00
0
16alpha,17alpha-Epoxypregnenolone acetate
34209-81-9 sc-224978
5 g
$29.00
0
Thiomuscimol
An analog used as a photoaffinity label for GABAA
62020-54-6 sc-213035
10 mg
$350.00
1
Isoguvacine HCl
An agonist of Gamma-amino butyric acid receptors
68547-97-7 sc-200451
sc-200451A
10 mg
50 mg
$25.00
$108.00
2
CGP 52432
A selective and effective GABAB receptor antagonist
139667-74-6 sc-361141
sc-361141A
10 mg
50 mg
$199.00
$825.00
0
Indiplon
A potent GABAAreceptor positive allosteric modulator
325715-02-4 sc-204011
sc-204011A
10 mg
50 mg
$129.00
$516.00
0
Phenylbenzene omega-phosphono-alpha-amino acid
A selective strychnine-sensitive GlyR antagonist
sc-301540
10 mg
$286.00
1
16-Dehydropregnenolone acetate
979-02-2 sc-224976
10 g
$238.00
0
(-)-Bicuculline methiodide
A N-methylated derivative of the GABAA antagonist (+)-bicuculline
40709-69-1 sc-200485
50 mg
$142.00
5
R-(+)-Baclofen hydrochloride
A seelctive GABAB receptor agonist
63701-55-3 sc-203229
sc-203229A
10 mg
50 mg
$30.00
$117.00
0
SKF-89976A
A GABA transporter type 1 inhibitor
85375-15-1 sc-253567
10 mg
$80.00
0
TPMPA
TPMPA is a competitive, selective GABAC antagonist
182485-36-5 sc-204352
sc-204352A
10 mg
50 mg
$215.00
$750.00
1
5alpha-Pregnan-3beta-ol-20-one 3beta-acetate
906-83-2 sc-233497
5 g
$215.00
0
Propybicyphat
A GABA-gated chloride channel blocker
51486-74-9 sc-301615
1 mg
$229.00
0
NCS-382 Sodium Salt
A γ-Hydroxybutyric acid antagonist
131733-92-1 sc-203444
sc-203444A
10 mg
50 mg
$82.00
$360.00
0
GABA
An inhibitory neurotransmitter in the CNS
56-12-2 sc-203053
sc-203053A
10 g
25 g
$40.00
$82.00
1
17alpha-Hydroxypregnenolone
A C21 steroid and prohormone in the formation of DHEA
387-79-1 sc-223186
5 g
$424.00
0
Thiocolchicoside
A GABAA receptor antagonist
602-41-5 sc-202839
sc-202839A
1 mg
5 mg
$30.00
$120.00
0
Hispidulin
A potent benzodiazepine (BZD) receptor ligand
1447-88-7 sc-203999
10 mg
$229.00
1
Pregnenolone sulfate sodium salt
A GABAA receptor antagonist
1852-38-6 sc-301609
50 mg
$60.00
0
Muscimol
A potent and specific GABAA receptor agonist/GABA analog
2763-96-4 sc-200460
sc-200460A
5 mg
25 mg
$96.00
$225.00
2
Valerenic acid
A positive allosteric modulator of the GABAA receptor
3569-10-6 sc-204377
sc-204377A
1 mg
10 mg
$53.00
$460.00
1
Chlormethiazole hydrochloride
Potentiates GABAA receptor function
6001-74-7 sc-203548
sc-203548A
10 mg
50 mg
$110.00
$385.00
0
Guvacine hydrochloride
Inhibits GABA uptake
6027-91-4 sc-263347
25 mg
$93.00
0
Dihydroergotoxine mesylate
Binds with high affinity to GABAA receptor
8067-24-1 sc-203921
100 mg
$109.00
0
trans-4-Hydroxycrotonic acid
A compound that binds to the GHB receptor with higher affinity than GHB
24587-49-3 sc-203710
sc-203710A
10 mg
50 mg
$89.00
$510.00
0
TACA
A GABAA and GABAC agonist
38090-53-8 sc-203705
sc-203705A
10 mg
50 mg
$90.00
$290.00
0
Tracazolate hydrochloride
A modulator of GABAA receptors
1135210-68-2 sc-203709
sc-203709A
10 mg
50 mg
$89.00
$359.00
0
Stiripentol
An inhibitor of CYP1A2, CYP2C19 and CYP3A4
49763-96-4 sc-208402
100 mg
$300.00
0
(-)-Bicuculline methochloride
A water-soluble GABAA antagonist
53552-05-9 sc-203528
sc-203528A
10 mg
50 mg
$109.00
$323.00
0
gamma-Acetylenic GABA
A GABA transaminase inhibitor
57659-38-8 sc-295002
sc-295002A
1 mg
5 mg
$200.00
$400.00
0
Gabaculine
A conformationally constrained analog of GABA
59556-17-1 sc-200473
sc-200473A
10 mg
50 mg
$300.00
$638.00
2
Vigabatrin
A selective GABA transaminase inhibitor
60643-86-9 sc-204382
sc-204382A
sc-204382B
sc-204382C
10 mg
50 mg
100 mg
1 g
$88.00
$359.00
$480.00
$700.00
0
THIP hydrochloride
A GABAA receptor agonist and GABAC receptor antagonist
64603-91-4 sc-204342
50 mg
$101.00
0
CL 218872
A benzodiazepine agonist selective for α1 subunit-containing GABAA receptors
66548-69-4 sc-203552
sc-203552A
10 mg
50 mg
$85.00
$319.00
0
3-Methyl-GABA
An activator of GABA aminotransferase
71424-95-8 sc-203471
sc-203471A
10 mg
50 mg
$119.00
$510.00
0
Nefiracetam
Activator of L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems
77191-36-7 sc-205766
sc-205766A
100 mg
250 mg
$125.00
$140.00
0
DMCM hydrochloride
A benzodiazepine inverse agonist
82499-00-1 sc-205295
sc-205295A
10 mg
50 mg
$185.00
$709.00
0
ZAPA sulfate
A selective potent GABAA receptor agonist
92138-10-8 sc-200471
sc-200471A
5 mg
25 mg
$71.00
$275.00
0
Topiramate
A GluR5 kainate receptor antagonist which also inhibits Nav channels, L-type Ca2+ channels, and carbonic anhydrase
97240-79-4 sc-204350
sc-204350A
10 mg
50 mg
$103.00
$355.00
0
Phaclofen
A selective GABAB receptor antagonist
114012-12-3 sc-200462
sc-200462A
5 mg
25 mg
$80.00
$328.00
0
2-Hydroxysaclofen
A selective GABAB antagonist
117354-64-0 sc-202011
sc-202011A
2.5 mg
10 mg
$87.00
$175.00
0
CGP 46381
A selective GABAB receptor antagonist
123691-14-5 sc-361140
sc-361140A
10 mg
50 mg
$175.00
$739.00
0
Saclofen
A selective GABAB antagonist
125464-42-8 sc-203252
10 mg
$175.00
0
SKF 97541
A very potent GABAB agonist/GABAC antagonist
127729-35-5 sc-200469
sc-200469A
5 mg
25 mg
$101.00
$450.00
0
FGIN-1-43
A specific ligand for mitochondrial diazepam binding inhibitor receptor
145040-29-5 sc-203953
sc-203953A
10 mg
50 mg
$119.00
$510.00
0
Tiagabine Hydrochloride
An uptake inhibitor of GABA and also an anticonvulsant
145821-59-6 sc-208437
10 mg
$160.00
0
(S)-SNAP 5114
A GABA uptake inhibitor that increases thalamic GABA levels
157604-55-2 sc-204257
sc-204257A
5 mg
25 mg
$110.00
$400.00
0
NNC 05-2090 hydrochloride
A GABA uptake inhibitor displaying selectivity for BGT-1 (mGAT-2) transporters
184845-43-0 sc-204131
sc-204131A
10 mg
50 mg
$199.00
$825.00
0
TB 21007
A GABAA receptor inverse agonist
207306-50-1 sc-204322
sc-204322A
10 mg
50 mg
$112.00
$630.00
0
Etbicyphat
A synthetic, non-competitive GABA antagonist
1005-93-2 sc-294479
500 mg
$420.00
0
R-(+)-Baclofen (free base)
A selective GABAB receptor agonist
69308-37-8 sc-203228
sc-203228A
10 mg
50 mg
$50.00
$195.00
0
FrPbAII
A GABA and glycine uptake inhibtor
sc-221630
5 mg
$450.00
0
6,2prime-Dihydroxyflavone
A partial inverse agonist at GABAA receptors with a-subunit selectivity
sc-300048
5 mg
$119.00
0
beta-Alanine
An endogenous glycine agonist and GABA transporter inhibitor
107-95-9 sc-364682
25 g
$20.00
0
21-Acetoxypregnenolone
566-78-9 sc-231272
1 g
$42.00
0
16alpha,17alpha-Epoxypregnenolone
974-23-2 sc-223173
sc-223173A
5 g
10 g
$45.00
$83.00
0
Mebicyphat
A noncompetitive GABA antagonist
1449-89-4 sc-295376
500 mg
$395.00
0
SCS
Potent and selective partial inhibitor of β1-containing GABAA receptors
3232-36-8 sc-203375
50 mg
$105.00
0
3alpha,12alpha-Dihydroxy-5beta-pregnan-20-one 3,12-diacetate
15991-93-2 sc-226347
50 mg
$50.00
0
16,17-Epoxy-21-acetoxypregnenolone
28444-97-5 sc-224977
1 g
$68.00
0
17alpha-Hydroxypregnenolone 3-acetate
41906-06-3 sc-224980
5 g
$175.00
0
CGP 13501
A positive allosteric modulator at GABAB receptors
56189-68-5 sc-203542
sc-203542A
10 mg
50 mg
$139.00
$585.00
0
CGP 7930
Positive allosteric modulator of GABAB receptors
57717-80-3 sc-203543
sc-203543A
10 mg
50 mg
$135.00
$520.00
0
S(+)-gamma-Vinyl-GABA
A selective GABA transaminase inhibitor
74046-07-4 sc-222279
sc-222279A
sc-222279B
sc-222279C
sc-222279D
5 mg
10 mg
50 mg
100 mg
250 mg
$440.00
$700.00
$1,683.00
$3,000.00
$5,000.00
0
ZK 93423 hydrochloride
A potent benzodiazepine agonist
83910-44-5 sc-204422
sc-204422A
10 mg
50 mg
$179.00
$750.00
0
SKF 89976A hydrochloride
A potent GABA uptake inhibitor
85375-85-5 sc-203266
sc-203266A
1 mg
10 mg
$30.00
$123.00
0
ZK 93426 hydrochloride
An elective and competitive benzodiazepine receptor antagonist
89592-45-0 sc-203727
sc-203727A
10 mg
50 mg
$149.00
$630.00
0
RO 15-4513
A high affinty benzodiazepine ligand and GABAA antagonist
91917-65-6 sc-203683
10 mg
$125.00
0
RO 19-4603
An agent that binds with high affinity to GABAA receptors
99632-94-7 sc-203684
sc-203684A
10 mg
50 mg
$125.00
$560.00
0
CI 966 hydrochloride
A selective inhibitor of GABA T-1
110283-66-4 sc-203891
sc-203891A
10 mg
50 mg
$169.00
$681.00
0
Loreclezole hydrochloride
A subtype-selective GABAA receptor agonist
117857-45-1 sc-204061
sc-204061A
10 mg
50 mg
$195.00
$825.00
0
Ganaxolone
A potent stereoselective modulator of GABAA receptors
38398-32-2 sc-203586
sc-203586A
10 mg
50 mg
$129.00
$560.00
0
L-655,708
A potent and selective inverse agonist for the benzodiazepine
130477-52-0 sc-204040
sc-204040A
5 mg
25 mg
$88.00
$263.00
0
rac BHFF
A GABAB receptor positive allosteric modulator
123557-91-5 sc-204228
sc-204228A
5 mg
25 mg
$110.00
$420.00
0
CGP 36216
A GABAB selective antagonist
123691-29-2 sc-362724
sc-362724A
10 mg
50 mg
$155.00
$712.00
0
NCS-382 hydrate
A GHB receptor antagonist
131733-92-1 sc-301458
10 mg
$75.00
0
U 90042
A GABAA receptor ligand
134516-99-7 sc-204362
sc-204362A
10 mg
50 mg
$155.00
$620.00
0
U 93631
A GABAA receptor antagonist
152273-12-6 sc-204364
sc-204364A
10 mg
50 mg
$169.00
$715.00
0
Org 20599
A positive allosteric modulator and agonist of GABA receptors
156685-94-8 sc-204150
sc-204150A
10 mg
50 mg
$185.00
$781.00
0
Pentylenetetrazole
A useful biochemical in neurotransmitter studies
54-95-5 sc-203345
sc-203345A
5 g
25 g
$40.00
$65.00
1
U 89843A
A positive allosteric modulator of GABAA receptors
157013-85-9 sc-204361
sc-204361A
10 mg
50 mg
$125.00
$525.00
0
SB 205384
A GABAA receptor modulator
160296-13-9 sc-204263
sc-204263A
10 mg
50 mg
$195.00
$825.00
0
Cloflubicyne
A potent non-competitive GABA antagonist
224790-70-9 sc-300382
1 mg
$260.00
0
5-Nitro-alpha-oxo-N-(1R)-phenylethyl]-1H-indole-3-acetamide
A GABA<sub>A</sub> α2 agonist
355022-97-8 sc-358561
sc-358561A
10 mg
50 mg
$135.00
$595.00
0
DS2
A positive allosteric modulator of δ-subunit containing GABA<sub>A</sub> receptors
374084-31-8 sc-294421
sc-294421A
10 mg
25 mg
$170.00
$700.00
0
17-PA
An antagonist of neurosteroid GABA potentiation
694438-95-4 sc-361075
sc-361075A
10 mg
50 mg
$239.00
$999.00
0
AA 29504
A positive allosteric modulator of GABAA receptors
945828-50-2 sc-361096
sc-361096A
5 mg
25 mg
$83.00
$350.00
0
Dansyl-gamma-Amino-n-Butyric Acid Cyclohexylammonium Salt
76563-43-4 sc-294267
sc-294267A
100 mg
250 mg
$30.00
$57.00
0

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.