Chloride Channel Modulators

Santa Cruz Biotechnology now offers a broad range of Chloride Channel Modulators. Chloride Channel Modulators affect the influx or efflux of chloride ions through chloride channels, which help maintain cell volume and set the resting membrane potential of cells. Calcium-activated chloride channels (CaCCs) and the cystic fibrosis transmembrane conductance regulator (CFTR) are two examples of the channels which can be affected by chloride channel modulators. These modulators work in various ways, often by physically blocking the channel to inhibit ion flow, and may be general or specific. Our popular products such as Fenamic acid and DIDS, Disodium Salt are typically available for immediate shipment.

indicates a highly recommended product based on customer preference.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Glyburide (Glibenclamide)
An ATP-dependent KIR6 and CFTR Cl- channel blocker
10238-21-8 sc-200982
sc-200982A
1 g
5 g
$32.00
$50.00
18
5-Nitro-2-(3-phenylpropylamino)benzoic Acid (NPPB)
A Cox inhibitor and GPR35 activator
107254-86-4 sc-201542
sc-201542A
10 mg
50 mg
$52.00
$227.00
4
IAA-94
A potent indanyloxyacetic acid blocker of epithelial chloride channels
54197-31-8 sc-201544
sc-201544A
10 mg
50 mg
$145.00
$475.00
2
Fipronil
A GluCl and GABA-gated-Cl channel blocker
120068-37-3 sc-201546
sc-201546A
20 mg
100 mg
$47.00
$201.00
0
Fenamic acid
A potent, non-specific blocker of Cl- channel and chloride-bicarbonate exchange
91-40-7 sc-202590
1 g
$20.00
1
9-AC
A chloride transport inhibitor with moderate to strong inhibitory action on PKA activated cardiac IcI
723-62-6 sc-203483
100 mg
$65.00
0
DCEBIO
An activator of hIK1 K+channels and apical Cl- conductance
60563-36-2 sc-203561
sc-203561A
10 mg
50 mg
$105.00
$409.00
1
Talniflumate
An inhibitor of Cox and Cl-/HCO3- exchange
66898-62-2 sc-203706
sc-203706A
10 mg
50 mg
$85.00
$359.00
0
Chromanol 293B
A blocker of the slow delayed rectifier K+ current
163163-23-3 sc-203889
sc-203889A
10 mg
50 mg
$155.00
$670.00
0
DCPIB
A selective and potent blocker of VSAC and inhibitor of glucose-stimulated insulin release
82749-70-0 sc-203913
10 mg
$145.00
1
DIDS, Disodium Salt
An anion transport inhibitor that inhibits Cl– uptake
67483-13-0 sc-203919
sc-203919A
sc-203919B
sc-203919C
250 mg
25 mg
100 mg
1 g
$170.00
$39.00
$120.00
$240.00
1
SFK1
678997-25-6 sc-215849
10 mg
$159.00
0
Duramycin
A chloride secretion enhancer in airway epithelium
1391-36-2 sc-239840
10 mg
$348.00
2
VRT-532
38214-71-0 sc-253832
5 mg
$118.00
0
Etbicyphat
A synthetic, non-competitive GABA antagonist
1005-93-2 sc-294479
500 mg
$420.00
0
PG 01
A transmembrane conductance regulator used for research purposes
853138-65-5 sc-358839
sc-358839A
5 mg
25 mg
$141.00
$544.00
0

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