Apoptosis Inducers

Santa Cruz Biotechnology offers a broad range of Apoptosis Inducers for use in conjunction with our extensive selection of research antibodies directed against tumor suppressors and proteins involved in apoptosis. Neoplastic growth arises from the dysregulation of cell growth, proliferation, and programmed death. Various tumor suppressors prevent such aberrant cell expansion by slowing progression of the cell cycle, or by inducing apoptosis. Apoptosis Inducers available below act on various apoptosis-related proteins to promote apoptotic cell death. Our popular products such as Puromycin dihydrochloride, Ionomycin, and Cisplatin are typically available for immediate shipment. View detailed information on all our available Apoptosis Inducers by linking to the specific product blocks.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Puromycin dihydrochloride
An aminonuclease antibiotic used for selection and maintenance of cell lines expressing a transfected pac gene
58-58-2 sc-108071
sc-108071A
sc-108071B
sc-108071C
25 mg
50 mg
250 mg
1 g
$30.00
$55.00
$167.00
$800.00
61
Monensin Sodium Salt
A monovalent cation ionophore and transporter
22373-78-0 sc-200109
1 g
$68.00
1
Sulindac sulfide
An active metabolite of sulindac that inhibits for Cox
32004-67-4 sc-200118
sc-200118A
5 mg
25 mg
$61.00
$195.00
2
Sulindac Sulfone
An inhibitor of growth and inducer of apoptosis in cancer cell lines
59864-04-9 sc-200120
sc-200120A
sc-200120B
5 mg
25 mg
100 mg
$81.00
$190.00
$368.00
2
Triptolide
An antiinflammatory immunosuppressive antibiotic
38748-32-2 sc-200122
sc-200122A
1 mg
5 mg
$80.00
$320.00
5
1,5-Isoquinolinediol
An inhibitor of PARP, NOS-2, and PARS
5154-02-9 sc-200127
sc-200127A
20 mg
100 mg
$57.00
$237.00
3
TPEN
An apoptosis inducer and heavy metal chelator
16858-02-9 sc-200131
100 mg
$96.00
2
Betulinic Acid
A cytotoxic, cell apoptosis causing agent that upregulates caspase-8
472-15-1 sc-200132
sc-200132A
25 mg
100 mg
$108.00
$325.00
0
Bleomycin Sulfate
A glycopeptide antibiotic
9041-93-4 sc-200134
sc-200134A
10 mg
50 mg
$200.00
$700.00
11
Bufalin
Inducer of apoptosis in human HL-60 and U-937 cell lines
465-21-4 sc-200136
10 mg
$97.00
1
Gambogic Acid
An apoptosis inducer in sever tumor cell lines via regulation of Bax and inhibition of Bcl-2 genes
2752-65-0 sc-200137
sc-200137A
5 mg
25 mg
$77.00
$309.00
4
2,3-DCPE
A compound that induces both upregulation and S-phase arrest in p21
1009555-55-8 sc-200139
sc-200139A
10 mg
25 mg
$63.00
$272.00
3
D-alpha-Tocopheryl Succinate
A potent antioxidant tocopherol
4345-03-3 sc-200141
1 g
$30.00
0
Desipramine hydrochloride
An inhibitor of norepinephrine, serotonin, and dopamine transporters
58-28-6 sc-200158
sc-200158A
100 mg
1 g
$44.00
$91.00
1
(+/-)-S-Nitroso-N-acetylpenicillamine
A cysteine protease inhibitor and spontaneous NO donor in physiological conditions
79032-48-7 sc-200319
sc-200319A
sc-200319B
20 mg
100 mg
10 mg
$64.00
$258.00
$43.00
5
S-Nitrosoglutathione (GSNO)
A spontaneously releasing nitric oxide donor which inhibits NFκB and platelet activation
57564-91-7 sc-200349
sc-200349A
10 mg
50 mg
$79.00
$295.00
3
Borrelidin
An anti-angiogenic and anti-microbial compound
7184-60-3 sc-200379
sc-200379A
100 µg
1 mg
$86.00
$215.00
0
Ursolic Acid
An antiangiogenic and antiproliferative agent
77-52-1 sc-200383
sc-200383A
50 mg
250 mg
$49.00
$168.00
0
Imiquimod
A TLR7 activator and angiogenesis inhibitor
99011-02-6 sc-200385
sc-200385A
100 mg
500 mg
$60.00
$268.00
3
Dihydrokainic acid
an EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
52497-36-6 sc-200442
sc-200442A
10 mg
50 mg
$186.00
$835.00
0
Kainic acid
An excitatory and excitotoxic glutamate-mimic kainate receptor agonist
487-79-6 sc-200454
sc-200454A
5 mg
25 mg
$64.00
$274.00
9
Esculetin
A hydroxyl radical and ROS scavenger that attenuates cellular oxidative stress
305-01-1 sc-200486
1 g
$31.00
0
Baicalein
An inhibitor of Ca2+ uptake, 5-LO, and 12-LO
491-67-8 sc-200494
sc-200494A
10 mg
100 mg
$30.00
$40.00
4
K-252a
A cell permeable protein kinase inhibitor
99533-80-9 sc-200517
sc-200517A
sc-200517B
100 µg
1 mg
500 µg
$118.00
$473.00
$200.00
3
Tyrphostin 47
A potent inhibitor of EGFR kinase activity
122520-86-9 sc-200543
sc-200543A
5 mg
25 mg
$77.00
$309.00
3
Bestatin hydrochloride
An inhibitor of aminopeptidases, LAP3, and leukotriene A4 hydrolase
65391-42-6 sc-200564
sc-200564A
sc-200564B
5 mg
25 mg
500 mg
$94.00
$334.00
$902.00
0
Tyrphostin 9
A PDGFR and calcium inhibitor
10537-47-0 sc-200568
sc-200568A
50 mg
250 mg
$66.00
$276.00
0
MK-886 sodium salt
A potent and selective inhibitor of FLAP and Cox-1
118427-55-7 sc-200608
sc-200608A
sc-200608B
5 mg
25 mg
1 mg
$112.00
$500.00
$45.00
3
Piceatannol
An inhibitor of Syk and NF-κB activation
10083-24-6 sc-200610
sc-200610A
1 mg
5 mg
$34.00
$62.00
3
BAY 11-7082
An anti-inflammatory agent and NFκB inhibitor
19542-67-7 sc-200615
sc-200615A
sc-200615B
10 mg
50 mg
5 mg
$81.00
$342.00
$60.00
52
Ro 31-8220
A cell-permeable PKC inhibitor that has been shown to be selective for PKC over CaM kinase II and PKA
138489-18-6 sc-200619
1 mg
$81.00
7
AG-1296
A potent inhibitor of PDGFR kinase and c-Kit
146535-11-7 sc-200631
sc-200631A
5 mg
25 mg
$117.00
$458.00
5
17-AAG
A potent Hsp90 inhibitor for tumor cells
75747-14-7 sc-200641
sc-200641A
1 mg
5 mg
$65.00
$150.00
8
Deguelin
An inhibitor of Cox-2
522-17-8 sc-200657
sc-200657A
5 mg
25 mg
$67.00
$268.00
0
AICAR
An inhibitor of the transcription of PPARα, the coactivation of PPARα
2627-69-2 sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$50.00
$150.00
$0.00
15
Triciribine
A tricyclic nucleoside that induces apoptosis and has antineoplastic and antiviral activity
35943-35-2 sc-200661
sc-200661A
1 mg
5 mg
$100.00
$180.00
11
DuP-697
A thiophene that inhibits Cox-2
88149-94-4 sc-200680
sc-200680A
5 mg
25 mg
$114.00
$465.00
0
PKC-412
A broad spectrum tyrosine kinase inhibitor
120685-11-2 sc-200691
sc-200691A
1 mg
5 mg
$114.00
$450.00
5
Ozagrel
A potent and selective thromboxane A2 inhibitor
82571-53-7 sc-200760
sc-200760A
10 mg
50 mg
$77.00
$325.00
4
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3)
A 5-LO inhibitor
10417-94-4 sc-200766
sc-200766A
100 mg
1 g
$80.00
$339.00
0
Linoleic Acid
A fatty acid with cytotoxic activity that influences the inflammatory process
60-33-3 sc-200788
sc-200788A
100 mg
1 g
$23.00
$52.00
1
Hinokitiol
An apoptosis inducer and potent metal chelator
499-44-5 sc-200812
sc-200812A
50 mg
250 mg
$62.00
$189.00
0
Cerulenin
An antibiotic fatty acid synthase (FAS) inhibitor
17397-89-6 sc-200827
sc-200827A
5 mg
10 mg
$113.00
$249.00
1
Simvastatin
A HMGCR inhibitor and anti-proliferative agent
79902-63-9 sc-200829
sc-200829A
50 mg
250 mg
$117.00
$473.00
8
Mastoparan
A G-protein activator
72093-21-1 sc-200831
1 mg
$95.00
0
Perillic Acid
An apoptosis inducing agent via an increase in p21, Bax, and caspase-3 in cells
23635-14-5 sc-200841
sc-200841A
100 mg
500 mg
$45.00
$192.00
0
Lovastatin
A hypocholesterolemic HMGCR inhibitor (statin that lowers cholesterol levels)
75330-75-5 sc-200850
sc-200850A
sc-200850B
5 mg
25 mg
100 mg
$20.00
$80.00
$320.00
5
Mevastatin (Compactin)
An HMGCR (HMG-CoA reductase) inhibitor
73573-88-3 sc-200853
sc-200853A
10 mg
50 mg
$69.00
$167.00
13
Geranylgeraniol
An intermediate in the mevalonate pathway
24034-73-9 sc-200858
sc-200858A
20 mg
100 mg
$79.00
$312.00
6
Brefeldin A
A fungal metabolite exhibiting a wide range of antibiotic activities and activator of caspase-3
20350-15-6 sc-200861
sc-200861A
sc-200861B
sc-200861C
5 mg
25 mg
100 mg
1 mg
$86.00
$304.00
$860.00
$48.00
5
PLAP
A phospholipase A2 activating peptide fragment consisting of 21 residues
137314-60-4 sc-200867
sc-200867A
100 µg
1 mg
$50.00
$110.00
0
Melittin
An apoptosis inducer, NF-κB inhibitor, and PLA2 activator
37231-28-0 sc-200868
500 µg
$93.00
0
Camptothecin
A reversible Mitochondrial Topo I inhibitor shown to exhibit antitumor activity
7689-03-4 sc-200871
sc-200871A
50 mg
250 mg
$46.00
$168.00
11
beta-Lapachone
A selective DNA topoisomerase I inhibitor
4707-32-8 sc-200875
sc-200875A
5 mg
25 mg
$70.00
$295.00
5
HC Toxin
An HDAC inhibitor
83209-65-8 sc-200884
1 mg
$152.00
0
Suberoyl bis-hydroxamic Acid
Inhibits histone deacetylation
38937-66-5 sc-200887
sc-200887A
100 mg
500 mg
$50.00
$104.00
0
ICRF-193
A bisdioxopiperazine which induces apoptosis and erythroid differentiation
21416-68-2 sc-200889
sc-200889A
1 mg
5 mg
$115.00
$467.00
2
Garcinol
A potent p300 and PCAF histone acetyltransferase inhibitor
78824-30-3 sc-200891
sc-200891A
10 mg
50 mg
$90.00
$342.00
2
Chaetocin
A lysine-specific histone methyltransferase inhibitor
28097-03-2 sc-200893
200 µg
$80.00
0
Cisplatin
An apoptosis inducer and caspase-3 activator
15663-27-1 sc-200896
sc-200896A
100 mg
500 mg
$70.00
$206.00
24
4-Hydroxyphenylretinamide
An agonist displaying activity at retinoid receptors
65646-68-6 sc-200900
sc-200900A
5 mg
25 mg
$104.00
$420.00
0
Troglitazone
A potent antiproliferative, apoptosis inducer, antioxidant, and antiinflammatory agent
97322-87-7 sc-200904
sc-200904A
5 mg
25 mg
$100.00
$412.00
4
Actinomycin D
A potent antibiotic that binds to the GpC steps of DNA
50-76-0 sc-200906
sc-200906A
5 mg
25 mg
$62.00
$224.00
3
Chromomycin A3
A G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye
7059-24-7 sc-200907
10 mg
$206.00
0
Daunorubicin hydrochloride
A DNA intercalator which may suppress acute leukemia proliferation
23541-50-6 sc-200921
sc-200921A
10 mg
50 mg
$96.00
$416.00
0
Doxorubicin hydrochloride
A Topo II inhibitor, DNA intercalator and powerful cytotoxic agent
25316-40-9 sc-200923
sc-200923A
5 mg
25 mg
$77.00
$309.00
9
PRIMA-1
A reactivator of p53 and inducer of apoptosis
5608-24-2 sc-200927
sc-200927A
5 mg
25 mg
$64.00
$267.00
0
Cyclopamine
A hedgehog [Hh] signaling pathway and Smo inhibitor
4449-51-8 sc-200929
sc-200929A
1 mg
5 mg
$90.00
$200.00
7
Tanshinone IIA
A transcription factor inhibitor
568-72-9 sc-200932
sc-200932A
5 mg
25 mg
$84.00
$304.00
9
12(S)-HETE
A potent stimulator of smooth muscle cell migration
54397-83-0 sc-200942
sc-200942A
50 µg
1 mg
$300.00
$3,200.00
1
15(S)-HETE
An arachidonic acid metabolite with immunosuppressive activity
54845-95-3 sc-200944
sc-200944A
50 µg
1 mg
$72.00
$829.00
0
13(S)-HPODE
A hydroperoxide formed from the oxidation of linoleic acid shown to inhibit platelet aggregation
33964-75-9 sc-200964
sc-200964A
50 µg
1 mg
$70.00
$803.00
4
Valinomycin
A potassium ionophore shown to induce cell death
2001-95-8 sc-200991
25 mg
$70.00
1
ET-18-OCH3
An inhibitor of phosphatidylinositol specific PLC & PKC
77286-66-9 sc-201021
sc-201021A
sc-201021B
5 mg
25 mg
50 mg
$50.00
$100.00
$150.00
1
Clioquinol
A metal chelating ligand that inhibits certain enzymes related to DNA replication
130-26-7 sc-201066
sc-201066A
1 g
5 g
$43.00
$111.00
0
Thioridazine Hydrochloride
A D2DR, D4DR, and calcium channel protein inhibitor
130-61-0 sc-201149
sc-201149A
1 g
5 mg
$47.00
$20.00
0
RGD peptide (GRGDNP)
An inhibitor of integrin-ligand interactions
114681-65-1 sc-201176
5 mg
$125.00
7
BRL-50481
A selective inhibitor of PDE 7
433695-36-4 sc-201178
sc-201178A
10 mg
50 mg
$72.00
$272.00
1
PGA2 (Prostaglandin A2)
An activator of intrinsic apoptotic pathways by affecting mitochondrial membrane permeability
13345-50-1 sc-201215
sc-201215A
1 mg
10 mg
$160.00
$400.00
0
delta12-PGJ2 (delta12-Prostaglandin J2)
A decomposition product of PGD2 showing potent antiviral and anti-proliferative activity
87893-54-7 sc-201257
sc-201257A
1 mg
5 mg
$341.00
$1,503.00
0
15-Deoxy-delta12,14-Prostaglandin J2
An endogenous PPARγ ligand and TRPA1 agonist
87893-55-8 sc-201262
sc-201262A
1 mg
5 mg
$112.00
$471.00
1
MG-132 [Z-Leu-Leu-Leu-CHO]
A proteasome and NF-κB inhibitor
133407-82-6 sc-201270
sc-201270A
5 mg
25 mg
$78.00
$295.00
42
Actinonin
An antibiotic shown to inhibit CD13, MMP-1,2,3,7,8,9,10,12, and MMP-13
13434-13-4 sc-201289
5 mg
$93.00
1
Gliotoxin
A toxic epipolythiodioxopiperazine metabolite that induces apoptosis and inhibits NF-κB
67-99-2 sc-201299
sc-201299A
2 mg
10 mg
$124.00
$374.00
0
2-Methoxyestradiol
A disruptor of microtubule function and HIF-1 inhibitor
362-07-2 sc-201371
sc-201371A
10 mg
50 mg
$69.00
$276.00
4
D-erythro-N,N-Dimethylsphingosine
A sphingosine kinase inhibitor
119567-63-4 sc-201373
sc-201373A
5 mg
25 mg
$67.00
$266.00
0
C2 Ceramide
A ser/thr protein phosphatase activator
3102-57-6 sc-201375
sc-201375A
5 mg
25 mg
$57.00
$217.00
2
Fumonisin B2
An inhibitor of sphingosine N-acyltransferase and a a cytotoxic analog of Fumonisin B1
116355-84-1 sc-201393
sc-201393A
1 mg
5 mg
$286.00
$1,150.00
0
Fumonisin B1
A serine and threonine phosphatase inhibitor
116355-83-0 sc-201395
sc-201395A
1 mg
5 mg
$70.00
$304.00
4
Myriocin (ISP-1)
An inhibitor of sphingolipid biosynthesis with immunosuppressive properties
35891-70-4 sc-201397
5 mg
$60.00
0
Bryostatin 1
A macrolactone marine natural product that binds to and modulates PKC
83314-01-6 sc-201407
10 µg
$149.00
0
LY 294002
A potent blocker of PI 3-kinase/Akt signaling
154447-36-6 sc-201426
sc-201426A
5 mg
25 mg
$119.00
$510.00
49
Vincristine Sulfate
A cell cycle arresting, apoptotic inducing alkaloid
2068-78-2 sc-201434
sc-201434A
5 mg
25 mg
$108.00
$425.00
6
Docetaxel
An antimitotic Taxol analog antibiotic
114977-28-5 sc-201436
sc-201436A
sc-201436B
5 mg
25 mg
250 mg
$74.00
$309.00
$1,040.00
5
Taxol
An antineoplastic and apoptosis inducing agent
33069-62-4 sc-201439
sc-201439A
sc-201439B
5 mg
25 mg
250 mg
$62.00
$203.00
$908.00
2
Vinblastine Sulfate
An anti-mitotic agent which arrests the cell cycle in the G2/M-phase
143-67-9 sc-201447
sc-201447A
10 mg
50 mg
$99.00
$390.00
8
Dolastatin 15
An apoptotic agent through Blc-2 phosphorylation
123884-00-4 sc-201449
1 mg
$198.00
2
3,5,4prime-Trimethoxystilbene
An antiangiogenic agent that is shown to inhibit endothelial cell proliferation
22255-22-7 sc-201450
sc-201450A
100 mg
500 mg
$65.00
$214.00
0
Evodiamine
An antiangiogenic and antiinflammatory agonist of TRPV1
518-17-2 sc-201479
sc-201479A
20 mg
100 mg
$26.00
$70.00
2
Nigericin sodium salt
A polyether antibioitc K+ and Na+ ionophore
28643-80-3 sc-201518
sc-201518A
5 mg
1 mg
$95.00
$38.00
2
Gingerol
An apoptosis inducing, anti-oxidative and anti-inflammatory agent
23513-14-6 sc-201519
sc-201519A
5 mg
20 mg
$105.00
$372.00
3
Oligomycin A
A mitochondrial ATPase inhibitor
579-13-5 sc-201551
sc-201551A
5 mg
25 mg
$115.00
$300.00
5
Embelin
An anti-nociceptive, anti-inflammatory, and anti-oxidant agent also shown to induce apoptosis
550-24-3 sc-201555
sc-201555A
10 mg
50 mg
$69.00
$276.00
2
8-Bromo-cAMP
A cAMP analog and cAMP-dependent PKA activator
76939-46-3 sc-201564
sc-201564A
10 mg
50 mg
$51.00
$161.00
7
Dibutyryl-cAMP
An analog of cyclic AMP that stimulates cAMP-dependent protein kinase
16980-89-5 sc-201567
sc-201567A
sc-201567B
20 mg
100 mg
500 mg
$37.00
$109.00
$400.00
11
1-beta-D-Arabinofuranosylcytosine
A cystosine analog and a potent inhibitor of replicative DNA synthesis
147-94-4 sc-201628
1 g
$141.00
0
4-Hydroxynonenal
An irreversible inhibitor of Na+/K+-ATPase activity
75899-68-2 sc-202019
sc-202019A
1 mg
10 mg
$72.00
$560.00
13
AG 825
A selective ErbB2 (Neu) inhibitor and apoptosis inducer
149092-50-2 sc-202045
sc-202045A
2 mg
5 mg
$60.00
$120.00
0
AG-490
A tyrosine kinase inhibitor of JAK2, EGFR, JAK3 and Neu
133550-30-8 sc-202046
sc-202046A
10 mg
50 mg
$78.00
$312.00
7
Alendronate, Sodium Salt
A robust inhibitor of bone resorption that induces apoptosis
121268-17-5 sc-202049
100 mg
$168.00
2
Apoptolidin
An apoptotic cell death inducer
194874-06-1 sc-202062
100 µg
$244.00
1
Arvanil
A cannabinoid CB1 and vanilloid TRPV1 (VR) agonist
128007-31-8 sc-202065
5 mg
$62.00
0
Bafilomycin B1
An inhibitor of vacuolar-ATPase enzymes in fungi
88899-56-3 sc-202072
1 mg
$166.00
2
Carboplatin
An antitumor agent that binds to DNA leading to apoptosis
41575-94-4 sc-202093
sc-202093A
25 mg
100 mg
$36.00
$120.00
6
Concanamycin A
An inhibitor of vacuolar type H+-ATPase (V-ATPase)
80890-47-7 sc-202111
sc-202111A
50 µg
200 µg
$56.00
$155.00
14