Apoptosis Inhibitors

Santa Cruz Biotechnology offers a broad range of Apoptosis Inhibitors for use in conjunction with our extensive selection of research antibodies directed against tumor suppressors and proteins involved in apoptosis. Neoplastic growth arises from the dysregulation of cell growth, proliferation, and programmed death. Various tumor suppressors prevent such aberrant cell expansion by slowing progression of the cell cycle, or by inducing apoptosis. Apoptosis Inhibitors available below act on various apoptosis-related proteins to inhibit apoptotic cell death. Our popular products such as Z-VAD-FMK, Z-VAD(OMe)-FMK, and Cyclosporin A are typically available for immediate shipment.

indicates a highly recommended product based on customer preference.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Z-VAD-FMK
Irreversible, cell-permeable, broad-spectrum caspase Inhibitor
187389-52-2 sc-3067
500 µg
$73.00
100
Z-VAD(OMe)-FMK
An irreversible and cell permeable broad-spectrum Caspase Inhibitor
187389-52-2 sc-311561
sc-311561A
1 mg
5 mg
$128.00
$500.00
59
Decylubiquinone
Inhibits the Ca2+-dependent mitochondrial permeability transition pore (MPTP) and also inhibits etoposide-induced apoptosis
55486-00-5 sc-358659
10 mg
$48.00
1
Sodium Orthovanadate
An inhibitor of several phosphatases and kinases
13721-39-6 sc-3540
sc-3540A
5 g
50 g
$19.00
$95.00
92
Calyculin A
A PP1 and PP2A-C inhibitor and tumor inducer
101932-71-2 sc-24000
sc-24000A
sc-24000B
sc-24000C
10 µg
100 µg
500 µg
1 mg
$55.00
$331.00
$1,365.00
$2,500.00
22
PMA
A reversible and highly potent protein kinase C (PKC) activator
16561-29-8 sc-3576
sc-3576A
sc-3576B
1 mg
5 mg
10 mg
$33.00
$109.00
$200.00
37
Cyclosporin A
A fungal metabolite calcineurin inhibitor
59865-13-3 sc-3503
sc-3503A
100 mg
500 mg
$55.00
$217.00
22
Necrostatin-1
An inhibitor of the necroptosis cell death pathway
4311-88-0 sc-200142
sc-200142A
20 mg
100 mg
$80.00
$320.00
32
Caffeine
An adenosine receptor antagonist and cAMP phosphodiesterase inhibitor
58-08-2 sc-202514
sc-202514A
sc-202514B
sc-202514C
5 g
100 g
250 g
1 kg
$20.00
$37.00
$55.00
$150.00
8
Autophagy Inhibitor, 3-MA
A multi-use inhibitor that protects cerebellar granule cells from apoptosis
5142-23-4 sc-205596
sc-205596A
50 mg
500 mg
$89.00
$468.00
34
MnTBAP chloride
A cell permeable superoxide dismutase mimetic and peroxynitrite scavenger
55266-18-7 sc-221954
sc-221954A
10 mg
50 mg
$33.00
$90.00
22
Salubrinal
A selective inhibitor of eIF-2α used to study ER stress-induced apoptosis
405060-95-9 sc-202332
sc-202332A
1 mg
5 mg
$32.00
$100.00
51
Calpeptin
A calpain-2, cathepsin L, and calpain-1 inhibitor
117591-20-5 sc-202516
sc-202516A
10 mg
50 mg
$107.00
$428.00
11
Caspase-3 Inhibitor
An inhibitor of caspase-3, caspase-6, caspase-7, and caspase-10
210344-95-9 sc-3075
0.5 mg
$100.00
18
KT5823
A selective inhibitor of cGKI and spontaneous apoptosis
126643-37-6 sc-3534
100 µg
$143.00
16
bpV(pic)
A potent protein PTP inhibitor
148556-27-8 sc-221379
sc-221379A
5 mg
25 mg
$84.00
$321.00
3
Calphostin C
An inhibitor of PKC, PKA, PKG, and calcium channel proteins
121263-19-2 sc-3545
sc-3545A
100 µg
1 mg
$104.00
$712.00
14
Caspase-8 inhibitor II
A potent, cell permeable, and irreversible inhibitor of caspase-8 and granzyme B
210344-98-2 sc-3084
1 mg
$226.00
26
Bongkrekic acid
An apoptosis inhibitor through prevention of PARP cleavage
11076-19-0 sc-205606
100 µg
$250.00
0
ABT 263
An inhibitor of antiapoptotic Bcl-2 proteins
923564-51-6 sc-207241
5 mg
$235.00
9
ALLN
A peptide aldehyde inhibitor of calpains and cathepsins
110044-82-1 sc-221236
5 mg
$85.00
6
Sodium phenylbutyrate
An HDAC inhibitor and caspase activator
1716-12-7 sc-200652
sc-200652A
1 g
10 g
$64.00
$150.00
7
2-Deoxy-D-glucose
An apoptosis and HXK inhibitor that lowers ATP levels in cancer cell lines
154-17-6 sc-202010
sc-202010A
1 g
5 g
$59.00
$200.00
9
Trolox
An antioxidant derived from water-soluble vitamin E
53188-07-1 sc-200810
sc-200810A
sc-200810B
sc-200810C
sc-200810D
500 mg
1 g
5 g
25 g
100 g
$25.00
$60.00
$216.00
$640.00
$1,600.00
13
SIRT1 Activator 3
A SIRT1 activator which also inhibits TNF-α
839699-72-8 sc-222315
sc-222315A
1 mg
5 mg
$102.00
$349.00
4
Melatonin
A neurohormone that upregulates antioxidant enzymes and inhibits rat NOS1
73-31-4 sc-207848
sc-207848A
sc-207848B
sc-207848C
sc-207848D
sc-207848E
1 g
5 g
25 g
100 g
250 g
1 kg
$53.00
$60.00
$200.00
$660.00
$1,140.00
$3,425.00
0
Hemin chloride
A porphyrin complex heme oxygenase-1 inducer with acts in cellular protection and control
16009-13-5 sc-202646
sc-202646A
sc-202646B
5 g
10 g
25 g
$88.00
$144.00
$304.00
1
Caspase-1 inhibitor VI
A cell-permeable, inhibitor of caspase-1, caspase-4, and caspase-5 activity
sc-3071
500 µg
$179.00
20
Muscone
A potent antiinflammatory agent, cytrochrome P-450 inducer, and apoptosis inhibitor
541-91-3 sc-200528
sc-200528A
100 mg
500 mg
$75.00
$245.00
2
MDL-28170
A cell permeable selective inhibitor of Calpain 1
88191-84-8 sc-201301
sc-201301A
10 mg
50 mg
$57.00
$222.00
10
Z-DEVD-FMK
An inhibitor of caspase-3, caspase-6, caspase-7, and caspase-10
210344-95-9 sc-311558
sc-311558A
1 mg
5 mg
$228.00
$970.00
24
Caspase-1 inhibitor I
An inhibitor of caspase-1, caspase-4, and caspase-5
143313-51-3 sc-358878
1 mg
$60.00
4
Hypericin
A kinase inhibitor with antiviral activity
548-04-9 sc-3530
sc-3530A
1 mg
5 mg
$58.00
$200.00
5
Thiorphan (DL)
An enkephalinase and metalloproteinase inhibitor
76721-89-6 sc-201287
sc-201287A
5 mg
25 mg
$147.00
$392.00
3
Caspase-1 Inhibitor II
An inhibitor of caspase-1, caspase-4, and caspase-5
178603-78-6 sc-300323
5 mg
$250.00
0
Q-VD-OPH
An inhibitor of caspase-3, caspase-1, caspase-8 and caspase-9
1135695-98-5 sc-222230
5 mg
$762.00
2
Z-VDVAD-FMK
An irreversible inhibitor of Caspase-2
sc-311562
1 mg
$275.00
4
Dexamethasone
A glucocorticoid which induces the production of phospholipase A2 inhibitory protein
50-02-2 sc-29059
sc-29059A
100 mg
5 g
$65.00
$251.00
12
Aurintricarboxylic Acid
A cell-permeable apoptosis inhibitor
4431-00-9 sc-3525
sc-3525A
sc-3525B
sc-3525C
100 mg
1 g
5 g
10 g
$20.00
$30.00
$46.00
$90.00
11
Maprotiline Hydrochloride
A norepinephrine reuptake inhibitor shown to block apoptosis of spiny neurons
10347-81-6 sc-200156
1 g
$72.00
3
Oxaliplatin
A potent anti-neoplastic agent that binds to DNA and shows efficacy in Cisplatin resistant cell lines
61825-94-3 sc-202270
sc-202270A
5 mg
25 mg
$98.00
$369.00
6
Carvedilol
An α1- and β-adrenergic receptor antagonist
72956-09-3 sc-200157
sc-200157A
100 mg
1 g
$57.00
$80.00
0
Heptelidic acid
An inhibitor of GAPDH and certain DNA polymerases
74310-84-2 sc-391051
1 mg
$379.00
0
JNK Inhibitor VIII
An inhibitor shown to suppress apoptosis, caspase cleavage, and cytochrome C release
894804-07-0 sc-202673
5 mg
$262.00
1
Mdivi-1
An inhibitor of mitochondrial division DRP1 and Dynamin I
338967-87-6 sc-215291
sc-215291A
5 mg
25 mg
$52.00
$200.00
4
HBED
An iron chelator and hydroxyl radical inhibitor
35369-53-0 sc-200817
sc-200817A
sc-200817B
50 mg
250 mg
1 g
$52.00
$211.00
$350.00
0
4-Amino-1,8-naphthalimide
A PARP-1 inhibitor
1742-95-6 sc-200125
sc-200125A
20 mg
100 mg
$76.00
$304.00
1
LY 364947
A selective ATP-competitive inhibitor of TGF-β Receptor I kinase
396129-53-6 sc-203122
sc-203122A
5 mg
10 mg
$103.00
$150.00
4
Gambogic amide
A selective agonist for Trk A
286935-60-2 sc-221655
sc-221655A
1 mg
5 mg
$88.00
$321.00
0
Ivachtin
A potent, cell-permeable, reversible, non-competitive inhibitor of caspase-3
745046-84-8 sc-224029
sc-224029A
1 mg
5 mg
$71.00
$143.00
0
Colivelin
A neuroprotective peptide and activator of STAT3
867021-83-8 sc-361153
500 µg
$265.00
0
3-Aminobenzamide
An inhibitor of PARP
3544-24-9 sc-3501
sc-3501A
sc-3501B
100 mg
5 g
1 g
$15.00
$50.00
$35.00
10
Ro 08-2750
A TrkA inhibitor and NGF-induced apoptosis inhibitor
37854-59-4 sc-203682
sc-203682A
1 mg
10 mg
$89.00
$175.00
0
7,8-Dihydroxyflavone
A TrkB agonist that inhibits glutamate-triggered apoptosis
38183-03-8 sc-278634
100 mg
$50.00
0
Omi/HtrA2 Protease Inhibitor, Ucf-101
A cell-permeable furfurylidine-thiobarbituric acid
313649-08-0 sc-222101
10 mg
$200.00
1
BI-6C9
A tBid inhibitor that possesses antiapoptotic properties
791835-21-7 sc-210915
sc-210915A
1 mg
5 mg
$47.00
$213.00
2
Orsellinic acid
A benzoic acid compound shown to block PAF-mediated neuronal apoptosis
480-64-8 sc-202752
1 mg
$135.00
0
Guanosine 3prime5prime-cyclic Monophosphate, Sodium Salt
An agent that interacts with the extracellular signals NO
40732-48-7 sc-202172
25 mg
$41.00
0
5-AIQ hydrochloride
A PARP-1 inhibitor
93117-07-8 sc-214307
sc-214307A
1 mg
5 mg
$73.00
$249.00
0
8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide monohydrochloride
A potent and selective antagonist of EP1 receptors
146033-02-5 sc-201344
sc-201344A
5 mg
25 mg
$58.00
$304.00
0
Pidotimod
A synthetic dipeptide with immunological modulatory activity on both the adaptive and innate immune responses
121808-62-6 sc-204846
sc-204846A
1 g
5 g
$95.00
$450.00
0
Boc-L-aspartic acid beta-benzyl ester chloromethylketone
An Apoptosis inhibitor
172702-58-8 sc-285170
sc-285170A
100 mg
250 mg
$517.00
$1,030.00
0
Bax channel blocker
A potent inhibitor of Bax-mediated mitochondrial cytochrome c release
335165-68-9 sc-203524
sc-203524A
10 mg
50 mg
$165.00
$700.00
1
Bax channel blocker
A cell-permeable dibromocarbazolo-piperazinyl derivative that displays anti-apoptotic properties
sc-221285
5 mg
$149.00
0
PD 151746
A selective non-peptidic calpain inhibitor
179461-52-0 sc-222134
5 mg
$188.00
1
PARP Inhibitor XII
A potent quinoxaline-based PARP inhibitor
sc-222126
5 mg
$379.00
0
Carbachol
An anti-apoptosis agent and TNF-α inhibitor
51-83-2 sc-202092
1 g
$82.00
4
MCI-186
A free radical scavenger that enhances NGF protein levels via the JNK pathway
89-25-8 sc-200806
sc-200806A
5 g
100 g
$20.00
$17.00
6
Sodium Pyruvate
An intermediate of sugar metabolism, an antioxidant, and an apoptosis inhibitor
113-24-6 sc-208397
sc-208397A
5 g
25 g
$21.00
$25.00
1
Damnacanthal
An immunomodulator and potent inhibitor of p56lck tyrosine kinase
477-84-9 sc-200611
1 mg
$232.00
1
p38 MAP Kinase Inhibitor IV
An ATP-competitive p38α/β MAPK inhibitor
1638-41-1 sc-204159
10 mg
$62.00
0
Razoxane
An inhibitor of Topo II
21416-67-1 sc-253425
sc-253425A
5 mg
25 mg
$72.00
$288.00
0
Myeloperoxidase Inhibitor-I
An irreversible and specific inhibitor of the peroxidation activity of MPO
5351-17-7 sc-204107
1 g
$90.00
0
Cesium Chloride
A useful compound for density gradient centrifugation and various molecular biology applications
7647-17-8 sc-203876
sc-203876A
100 g
1 kg
$150.00
$540.00
0
R(-)-Deprenyl hydrochloride
A neuroprotective agent and inhibitor of MAO-B
14611-52-0 sc-200742
sc-200742A
sc-200742B
100 mg
250 mg
1 g
$31.00
$75.00
$275.00
0
Amifostine
A broad radio-chemoprotector that restores mutant p53 activity
20537-88-6 sc-200937
sc-200937A
10 mg
50 mg
$71.00
$294.00
4
Bilobalide
A compound with neuroprotective, antibacterial, and inhibitory effects
33570-04-6 sc-201061
sc-201061A
10 mg
50 mg
$65.00
$275.00
3
Apoptosis Inhibitor
A cell-permeable inhibitor of apoptosis induction
54135-60-3 sc-205595
10 mg
$160.00
0
alpha-Tocotrienol
An antioxidant
58864-81-6 sc-221191
sc-221191A
sc-221191B
1 mg
5 mg
10 mg
$42.00
$190.00
$337.00
1
Cyclosporin A-d4
A group of nonpolar cyclic oligopeptides with immunosupppressant activity
59865-13-3 (unlabeled) sc-217987
1 mg
$550.00
0
Necrostatin-1 inactive control
A cell permeable thiohydantoin analog of Nec-1
64419-92-7 sc-204815
5 mg
$171.00
3
Cinnamtannin B-1
A potent antioxidant and Cox-2 inhibitor
88082-60-4 sc-202997
5 mg
$237.00
0
Ipsapirone
A selective SR-1A agonist
95847-70-4 sc-203607
sc-203607A
10 mg
50 mg
$129.00
$525.00
0
Tyrphostin AG 99
A potent, cell-permeable and reversible inhibitor of EGFR and EGF-dependent cell proliferation
118409-59-9 sc-202847
sc-202847A
5 mg
25 mg
$54.00
$184.00
0
3-ATA
A selective cyclin-dependent kinase 4 (CDK4) inhibitor
129821-08-5 sc-202414
5 mg
$289.00
0
PAPA NONOate
An NO donor which suppresses the caspase apoptotic cascade
146672-58-4 sc-202272
sc-202272A
5 mg
25 mg
$23.00
$90.00
9
Z-Asp-2,6-dichlorobenzoyloxymethylketone
A broad Caspase Inhibitor
153088-73-4 sc-202386
sc-202386A
10 mg
50 mg
$93.00
$402.00
0
Okadaic Acid, Ammonium Salt
A protein phosphatase regulator
155716-06-6 sc-202260
25 µg
$62.00
10
Rasagiline Mesylate
A selective irreversible MAO-B inhibitor
161735-79-1 sc-206071
sc-206071A
25 mg
100 mg
$125.00
$250.00
0
7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
A CK2 inhibitor
300675-28-9 sc-223742
sc-223742A
1 mg
5 mg
$26.00
$110.00
0
TGF-beta RI Kinase Inhibitor III
An inhibitor of activin receptor-like kinase 4
356559-13-2 sc-204341
2 mg
$198.00
0
Cdk2 substrate
sc-3056
0.5 mg/0.1 ml
$88.00
0
NS3694
A suppressor of the formation of apoptosome Apaf-1
426834-38-0 sc-203823
10 mg
$120.00
0
BEPP monohydrochloride
A double-strand RNA-dependent protein kinase (PKR) activator
455311-98-5 sc-214594
sc-214594A
5 mg
25 mg
$133.00
$544.00
0
GW-441756
A specific TrkA tyrosine kinase inhibitor
504433-23-2 sc-200683
sc-200683A
10 mg
50 mg
$141.00
$565.00
2
CAY10500
A TNFα inhibitor that prevents binding to the TNF Receptor 1
869998-49-2 sc-223865
sc-223865A
500 µg
1 mg
$72.00
$184.00
0
Bongkrekic Acid, Triammonium Salt
1177154-51-6 sc-311298
500 µg
$638.00
0
CAY10578
A potent inhibitor of CK2 that is also ATP competitive
19231-60-8 sc-205238
sc-205238A
1 mg
10 mg
$20.00
$128.00
0
Fructose-proline
Useful in inhibiting cancer metastasis and inducing apoptosis
29118-61-4 sc-391500
10 mg
$300.00
0
Linomide
An immunomodulator and apoptosis inhibitor
84088-42-6 sc-204057
sc-204057A
10 mg
50 mg
$159.00
$670.00
0
BTZO 1
A binder of the macrophage migration inhibitory factor (MIF)
99420-15-2 sc-362720
sc-362720A
5 mg
25 mg
$101.00
$398.00
0
(+/-)-Huperzine A
An NMDA antagonist
120786-18-7 sc-218582
1 mg
$55.00
0
7-nitro-10-octyl-3-phenyl-pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
137346-42-0 sc-352980
sc-352980A
1 mg
5 mg
$75.00
$331.00
0
Hexarelin
A growth hormone capable of apoptosis inhibition
140703-51-1 sc-394429
1 mg
$265.00
0
Suptopin-2
331852-66-5 sc-253617
10 mg
$217.00
0
iMAC2
A mitochondrial apoptosis-induced channel (MAC) inhibitor
335166-00-2 sc-362750
sc-362750A
10 mg
50 mg
$179.00
$825.00
0
R5C3
An MDM2 inhibitor and probe for fluorescence polarization binding assay
753504-14-2 sc-215783
5 mg
$91.00
0
BBMP
A mitochondrial PTP inhibitor
97120-13-3 sc-214575
sc-214575A
5 mg
25 mg
$200.00
$592.00
0
U 82836E
An iron-dependent lipid peroxidation inhibitor
137018-55-4 sc-204360
sc-204360A
sc-204360B
sc-204360C
25 mg
50 mg
100 mg
1 g
$29.00
$54.00
$128.00
$1,000.00
0
AG 490, m-CF3
An apoptotic and antiproliferative compound
581797-29-7 sc-221221
10 mg
$149.00
0
Maslinic Acid
A pentacyclic triterpene with antiproliferative properties
4373-41-5 sc-221873
sc-221873A
1 mg
5 mg
$32.00
$190.00
0
Me-7BIO
A control compound for 6BIO and 7BIO
sc-221878
1 mg
$99.00
0
thio-Miltefosine
An inhibitor of phosphocholine cytidylyl transferase
sc-222351
sc-222351A
1 mg
5 mg
$33.00
$150.00
0
Ginkgolide J
Reduces apoptotic damage in chick embryonic neurons
107438-79-9 sc-203968
sc-203968A
1 mg
5 mg
$90.00
$286.00
0
Terameprocol
A synthetic derivative of NDGA and non-selective lipoxygenase inhibitor
24150-24-1 sc-224304
sc-224304A
50 mg
100 mg
$20.00
$23.00
0
Sodium Ursodeoxycholate
NTCP inhibitor
2898-95-5 sc-296407
25 g
$320.00
0
Didox
A synthetic antioxidant that reduces oxidative injury levels
69839-83-4 sc-221539
sc-221539A
1 mg
5 mg
$20.00
$72.00
0
Pyruvic acid
A biochemical to cultivate undescribed soil bacteria and to develop a new method for determination of organic acids
127-17-3 sc-208191
sc-208191A
25 g
100 g
$39.00
$92.00
0
Taurodeoxychloic acid
An apoptosis inhibitor
516-50-7 sc-212991
10 mg
$280.00
0
Pentachloropyridine
A halogenated pyridine with antineoplastic and antiapoptic properties
2176-62-7 sc-279952
100 g
$108.00
0
Biotin-VAD-FMK
A cell permeable biotin-labeled caspase inhibitor
sc-311290
sc-311290A
1 mg
5 mg
$390.00
$1,900.00
0
NAP
A neuroprotective peptide
211439-12-2 sc-391778
sc-391778A
0.5 mg
1 mg
$62.00
$106.00
0
Glycidyl Palmitate
A chemical used for preparation of lysophosphatidic acids which inhibit apoptosis
7501-44-2 sc-396135
100 mg
$300.00
0
Z-WEHD-FMK
An inhibitor of caspase-1, caspase-4, caspase-5 and caspase-8
sc-3078
1 mg
$166.00
0
Z-AEVD-FMK
A caspase inhibitor designed to be cell permeable
1135688-47-9 sc-311557
5 mg
$640.00
0
NSC348884
A biochemical which inhibitss NPM oligomer formation, upregulates p53 and induces apoptosis
81624-55-7 sc-301483
5 mg
$79.00
0
DL-alpha-Difluoromethylornithine hydrochloride
An irreversible inhibitor of ornithine decarboxylase
68278-23-9 sc-252762
sc-252762A
sc-252762B
25 mg
10 mg
50 mg
$161.00
$69.00
$259.00
0
GW1929
A high-affinity agonist of PPARγ
196808-24-9 sc-300778
5 mg
$157.00
0
Ferrostatin 1
A potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis
347174-05-4 sc-498126
10 mg
$149.00
0

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