c-Abl Inhibitors

Santa Cruz Biotechnology now offers a broad range of c-Abl Inhibitors. c-Abl is an oncogene, initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV). c-Abl is implicated in several human leukemias including 90-95% of chronic myelocytic leukemia, 20-25% of adult acute lymphoblastic leukemia and 2-5% of pediatric acute lymphoblastic leukemia. c-Abl Inhibitors offered by Santa Cruz inhibit c-Abl and, in some cases, other cell signaling and leukemia related proteins. View detailed c-Abl Inhibitor specifications, including c-Abl Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
ZM-306416
A receptor tyrosine kinase inhibitor that has been shown to disrupt Flt and Flk activity
690206-97-4 sc-200676
sc-200676A
1 mg
10 mg
$75.00
$152.00
0
Imatinib mesylate
A c-Abl, PDGFR, and c-kit inhibitor
220127-57-1 sc-202180
sc-202180A
25 mg
100 mg
$37.00
$101.00
35
Nilotinib
A rationally designed c-Abl and Bcr-Abl kinase inhibitor
641571-10-0 sc-202245
sc-202245A
10 mg
25 mg
$196.00
$395.00
4
VEGFR2 Kinase Inhibitor III
A VEGFR2, Met, RET, PDGFR, and ALK inhibitor
204005-46-9 sc-202851
5 mg
$77.00
4
1-Naphthyl PP1
A selective inhibitor of v-Src and c-Fyn as well as c-Abl
221243-82-9 sc-203765
sc-203765A
10 mg
50 mg
$225.00
$945.00
0
Bcr-abl Inhibitor
An inhibitor of c-Abl and Bcr-abl activity
778270-11-4 sc-203836
5 mg
$149.00
1
WHI-P 154
A JAK3 inhibitor which inhibits other common kinases
211555-04-3 sc-204395
sc-204395A
10 mg
50 mg
$109.00
$615.00
0
Chlorogenic Acid
A Bcr-Abl inhibitor
327-97-9 sc-204683
sc-204683A
500 mg
1 g
$40.00
$62.00
0
PDGFR Tyrosine Kinase Inhibitor IV
An indenopyrazole agent that displays potent antiproliferative properties
627518-40-5 sc-205794
sc-205794A
1 mg
5 mg
$26.00
$135.00
0
N-Desmethyl Imatinib
A metabolite of Imatinib
404844-02-6 sc-208027
500 µg
$350.00
2
Dasatinib (monohydrate)
An inhibitor of Src family kinases, including c-Abl and Bcr-Abl tyrosine kinase activity
863127-77-9 sc-218081
sc-218081A
10 mg
100 mg
$80.00
$300.00
6
Bcr-abl Inhibitor II
An inhibitor of c-Abl and SRC kinases
607702-99-8 sc-221289
5 mg
$209.00
0
Imatinib
An inhibitor of multiple tyrosine kinases
152459-95-5 sc-267106
10 mg
$203.00
9
Adaphostin
A Bcr-Abl (the fusion protein of Bcr and c-Abl) tyrosine kinase inhibitor
241127-58-2 sc-291833
sc-291833A
10 mg
50 mg
$129.00
$560.00
0
Tyrene CR4
An inhibitor of JAK2 and Bcr-Abl (the fusion protein of Bcr and c-Abl)
1110670-40-0 sc-296677
5 mg
$99.00
0
PP121
An inhibitor of c-Abl, PI 3-kinase, PDGFR, Hck, FRAP, Flk-1, SRC, and DNA-PK
1092788-83-4 sc-301605
5 mg
$139.00
0
Herbimycin A
An inhibitor of c-Abl, HSP 90, c-Src, c-Yes, Fes, and Ros
70563-58-5 sc-3516
sc-3516A
100 µg
1 mg
$151.00
$940.00
11
Dasatinib
A chemical directly targets wild-type and mutant c-Abl kinase domains
302962-49-8 sc-358114
sc-358114A
25 mg
1 g
$36.00
$132.00
19
AP 24534
A Bcr-Abl (Bcr and c-Abl fusion), FGFR, and Flk-1 inhibitor
943319-70-8 sc-362710
sc-362710A
10 mg
50 mg
$169.00
$945.00
0
Bcr-abl Inhibitor III
A suppressor of the proliferation of Bcr-abl-expressing Ba/F3
778277-15-9 sc-364428
10 mg
$113.00
0
DCC-2036
A potent inhibitor against purified native and various mutants of Abl1
1020172-07-9 sc-364482
sc-364482A
10 mg
50 mg
$480.00
$1,455.00
0
PD-180970
A potent inhibitor of the p210 Bcr-Abl tyrosine kinase
287204-45-9 sc-364568
sc-364568A
5 mg
25 mg
$115.00
$425.00
0
WP1130
A selective deubiquitinase inhibitor and also suppresses Bcr/Abl
856243-80-6 sc-364650
sc-364650A
10 mg
50 mg
$480.00
$1,455.00
0
AT9283
An inhibitor of Aurora A, Aurora B, JAK3, JAK2, and c-Abl
896466-04-9 sc-364738
sc-364738A
2 mg
10 mg
$180.00
$400.00
0

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