The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKBβ or RacPK-β) and Akt 3 (also designated PKBγ or thyoma viral proto-oncogene 3). Akt1 and Akt2 are activated by PDGF stimulation. The activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor Wortmannin, suggesting that the protein signals downstream of the PI kinases. Akt1 Substrates offered by Santa Cruz affects Akt1 and, in some cases, other serine/threonine kinases and oncogene related proteins. View detailed Akt1 Substrate specifications, including Akt1 Substrate CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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