Tyrosine Kinase Inhibitors

Santa Cruz Biotechnology now offers a broad range of Tyrosine Kinase Inhibitors. Tyrosine kinases are enzymes responsible for activation of signal transduction cascades by phosphorylation of various proteins. Most tyrosine kinases have an associated protein tyrosine phosphatase, which removes the phosphate group. Tyrosine Kinase Inhibitors may also be called tyrphostins, the short name for "tyrosine phosphorylation inhibitor". Tyrosine Kinase Inhibitors offered by Santa Cruz inhibit Tyrosine Kinase and, in some cases, other phosphorylation and protein tyrosine phosphatase related proteins. View detailed Tyrosine Kinase Inhibitor specifications, including Tyrosine Kinase Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Imatinib mesylate
A c-Abl, PDGFR, and c-kit inhibitor
220127-57-1 sc-202180
sc-202180A
25 mg
100 mg
$37.00
$101.00
35
Caffeic acid phenethyl ester
Inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities
104594-70-9 sc-200800
sc-200800A
sc-200800B
20 mg
100 mg
1 g
$40.00
$130.00
$500.00
7
AG-490
A tyrosine kinase inhibitor of JAK2, EGFR, JAK3 and Neu
133550-30-8 sc-202046
sc-202046A
10 mg
50 mg
$78.00
$312.00
12
Src kinase inhibitor I
A potent dual site inhibitor of Src family kinases
179248-59-0 sc-204303
sc-204303A
1 mg
10 mg
$51.00
$196.00
8
2prime-Deschloro-2prime-hydroxy Dasatinib
A derivative of Dasatinib
sc-214069
1 mg
$350.00
0
Tyrphostin A23
An agent that blocks EGF-dependent autophosphorylation
118409-57-7 sc-3554
10 mg
$79.00
12
Daidzein
An inactive analog of genistein, a tyrosine kinase inhibitor and an estrogen receptor activator
486-66-8 sc-24001
sc-24001A
sc-24001B
100 mg
500 mg
5 g
$20.00
$30.00
$100.00
11
Genistein
A highly specific inhibitor of protein tyrosine kinase (PTK)
446-72-0 sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
100 mg
500 mg
1 g
5 g
10 g
25 g
$25.00
$90.00
$118.00
$304.00
$490.00
$890.00
20
Piceatannol
An inhibitor of Syk and NF-κB activation
10083-24-6 sc-200610
sc-200610A
1 mg
5 mg
$34.00
$62.00
6
Tyrphostin AG 1295
A selective inhibitor of platelet-derived growth factor (PDGF) tyrosine receptor kinase
71897-07-9 sc-3558
sc-3558A
5 mg
25 mg
$95.00
$255.00
8
PP1 Analog II, 1NM-PP1
A cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases
221244-14-0 sc-203214
sc-203214A
1 mg
5 mg
$94.00
$500.00
1
PD173074
Potent inhibitor of FGF and VEGF (Flt/Flk) receptors
219580-11-7 sc-202610
sc-202610A
sc-202610B
1 mg
5 mg
50 mg
$45.00
$137.00
$667.00
6
AG 126
Selectively inhibits phosphorylation of ERK 1 and ERK 2
118409-62-4 sc-3528
sc-3528A
5 mg
25 mg
$92.00
$365.00
4
PP 2
An effective and selective inhibitor of Src family kinases
172889-27-9 sc-202769
1 mg
$84.00
19
Lck Inhibitor
A cell-permeable ATP-competitive inhibitor of Lck
213743-31-8 sc-204052
1 mg
$200.00
3
Sunitinib Malate
An antineoplastic agent, Flk-1 inhibitor, and ATP-competitve inhibitor of PDGFRβ
341031-54-7 sc-220177
sc-220177A
10 mg
100 mg
$179.00
$450.00
4
N-Desmethyl Imatinib
A metabolite of Imatinib
404844-02-6 sc-208027
500 µg
$350.00
2
VEGFR2 Kinase Inhibitor III
A VEGFR2, Met, RET, PDGFR, and ALK inhibitor
204005-46-9 sc-202851
5 mg
$77.00
4
PDGFR Tyrosine Kinase Inhibitor III
An ATP-competitive PDGFR inhibitor
205254-94-0 sc-204173
1 mg
$156.00
2
Herbimycin A
An inhibitor of c-Abl, HSP 90, c-Src, c-Yes, Fes, and Ros
70563-58-5 sc-3516
sc-3516A
100 µg
1 mg
$151.00
$940.00
11
Emodin
A potent Lck tyrosine kinase inhibitor shown to suppress Neu tyrosine kinase activity
518-82-1 sc-202601
sc-202601A
50 mg
250 mg
$95.00
$250.00
1
Caffeic acid methyl ester
An antioxidant ornithine decarboxylase inhibitor
3843-74-1 sc-204664
50 mg
$48.00
0
1-Naphthyl PP1
A selective inhibitor of v-Src and c-Fyn as well as c-Abl
221243-82-9 sc-203765
sc-203765A
10 mg
50 mg
$225.00
$945.00
0
Sorafenib Tosylate
An inhibitor of Flk-1 (VEGFR), PDGFR and Raf kinases
475207-59-1 sc-357801
sc-357801A
100 mg
1 g
$100.00
$300.00
3
Sos SH3 domain Inhibitor
A synthetic inhibitor for Sos
159088-48-9 sc-3124
0.5 mg
$89.00
1
Butein
Inhibits the tyrosine kinase activity of the EGF receptor and p60c-src
487-52-5 sc-202510
sc-202510A
5 mg
50 mg
$169.00
$300.00
4
Leflunomide
An inhibitor of Cox-2 and tyrosine kinase
75706-12-6 sc-202209
sc-202209A
10 mg
50 mg
$20.00
$79.00
3
HNMPA
An inhibitor of insulin receptor tyrosine kinase
120943-99-9 sc-205714
sc-205714A
5 mg
25 mg
$71.00
$296.00
2
Tyrphostin 47
A potent inhibitor of EGFR kinase activity
122520-86-9 sc-200543
sc-200543A
5 mg
25 mg
$77.00
$309.00
4
Tyrphostin AG 112
An EGFR inhibitor
144978-82-5 sc-222381
5 mg
$23.00
0
AG-1296
A potent inhibitor of PDGFR kinase and c-Kit
146535-11-7 sc-200631
sc-200631A
5 mg
25 mg
$117.00
$458.00
5
PP 1
A selective and potent Src family tyrosine kinase inhibitor
172889-26-8 sc-203212
sc-203212A
1 mg
5 mg
$82.00
$139.00
2
WHI-P 154
A JAK3 inhibitor which inhibits other common kinases
211555-04-3 sc-204395
sc-204395A
10 mg
50 mg
$109.00
$615.00
0
RWJ 67657
A p38/JNK kinase inhibitor with anti-inflammatory properties
215303-72-3 sc-204251
sc-204251A
10 mg
50 mg
$185.00
$772.00
1
PDGFR Tyrosine Kinase Inhibitor IV
An indenopyrazole agent that displays potent antiproliferative properties
627518-40-5 sc-205794
sc-205794A
1 mg
5 mg
$26.00
$135.00
0
AZD8931
A potent inhibitor of EGFR phosphorylation
848942-61-0 sc-364426
sc-364426A
5 mg
10 mg
$255.00
$480.00
0
Tyrphostin A1
An inactive Tyrphostin used as a negative control for Tyrphostin A23
2826-26-8 sc-3559
sc-3559A
25 mg
100 mg
$147.00
$179.00
1
Compound 56
A potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor
171745-13-4 sc-203430
500 µg
$164.00
2
Syk Inhibitor II
A cell-permeable pyrimidine-carboxamide compound that acts as a potent, selective, and ATP-competitive inhibitor of Syk (IC50 = 41 nM)
227449-73-2 sc-281683
1 mg
$500.00
0
Amuvatinib
A multi-targeted tyrosine kinase inhibitor of PDGF and c-Kit
850879-09-3 sc-364402
sc-364402A
5 mg
10 mg
$379.00
$500.00
0
ST638
A protein tyrosine kinase inhibitor and PLD inhibitor
107761-24-0 sc-202344
5 mg
$121.00
0
DMPQ dihydrochloride
A potent and selective inhibitor of PDGFRβ tyrosine kinase
137206-97-4 sc-203927
sc-203927A
10 mg
50 mg
$145.00
$605.00
0
Tyrphostin AG 879
A protein tyrosine kinase inhibitor with potent effects on TrkA
148741-30-4 sc-3557
sc-3557A
5 mg
25 mg
$83.00
$328.00
2
Brutonprimes Tyrosine Kinase Inhibitor III
A highly potent, selective, and irreversible inhibitor of BTK
sc-311301
1 mg
$390.00
0
Tyrphostin AG 808
C18H12N2O3 sc-364205
20 mg
$300.00
0
Kojic acid
A tyrosine kinase inhibitor that acts as a chelation agent which inhibits melanin production.
501-30-4 sc-255228
sc-255228A
5 g
10 g
$90.00
$170.00
0
Genistin
An isoflavone glycoside which is an inactive analog of the PTK inhibitor Genistein
529-59-9 sc-202168
5 mg
$188.00
0
Nifuroxazide
An inhibitor of STAT activation and signaling activity
965-52-6 sc-204128
sc-204128A
500 mg
5 g
$195.00
$500.00
4
JAK3 Inhibitor V
A selective JAK3 inhibitor
4452-06-6 sc-295218
10 mg
$125.00
0
VEGFR2 Kinase Inhibitor I
A highly selective and cell-permeable tyrosine kinase inhibitor
15966-93-5 sc-202850
1 mg
$150.00
0
AGL 2043
A cell permeable compound that acts as a potent inhibitor of type III receptor tyrosine kinases
22617-28-8 sc-203808
1 mg
$295.00
0
Tyrphostin A25
A cell-permeable, reversible, and competitive protein tyrosine kinase (PTK) substrate inhibitor
118409-58-8 sc-3555
sc-3555A
25 mg
5 mg
$276.00
$67.00
8
Tyrphostin AG 30
A potent PTK inhibitor
122520-79-0 sc-202042
sc-202042A
5 mg
10 mg
$33.00
$80.00
0
Lavendustin B
A tyrosine kinase inhibitor
125697-91-8 sc-200595
sc-200595A
1 mg
5 mg
$64.00
$249.00
1
Aminogenistein
An inhibitor of p56Ick protein-tyrosine kinase activity
132018-32-7 sc-207279
10 mg
$220.00
0
AG-370
A selective inhibitor of PDGFR kinase
134036-53-6 sc-205203
sc-205203A
1 mg
10 mg
$90.00
$392.00
0
RG-13022
An inhibitor of the EGF and PDGF receptor tyrosine kinases
136831-48-6 sc-200591
sc-200591A
5 mg
10 mg
$95.00
$175.00
1
Tyrphostin RG 14620
A non-phenolic tyrphostin analog selective for the EGF receptor
136831-49-7 sc-200593
sc-200593A
5 mg
10 mg
$64.00
$130.00
0
Tyrphostin AG 957
A potent tyrosine kinase inhibitor
140674-76-6 sc-204359
sc-204359A
1 mg
5 mg
$36.00
$133.00
0
trans-1-(3prime-Carboxy-4prime-hydroxyphenyl)shy-2-(2,5-dihydroxyphenyl)shyethene
A tyrosine kinase inhibitor that shows extremely high potency against immunoprecipitated p56lck
150258-63-2 sc-208455
2.5 mg
$280.00
0
PD 158780 solution
A potent tyrosine kinase inhibitor
171179-06-9 sc-202758
500 µg
$159.00
0
PD 158780
A potent tyrosine kinase inhibitor that can permeate cells
171179-06-9 sc-358789
10 mg
$127.00
0
BPIQ-II HCl Salt
A specific and potent EGFR tyrosine kinase activity inhibitor
171179-32-1 (free base) sc-221375
1 mg
$203.00
0
AAF-CMK
A serine protease inhibitor that inhibits tripeptidyl peptidase II (TPPII)
184901-82-4 sc-205591
sc-205591A
5 mg
25 mg
$57.00
$225.00
1
SU 4984
An Flg tyrosine kinase inhibitor
186610-89-9 sc-205977
1 mg
$63.00
0
3-(4-Isopropylbenzylidenyl)shyindolin-2-one
A non-selective inhibitor of RTKs
186611-55-2 sc-202413
sc-202413A
1 mg
5 mg
$39.00
$206.00
0
PD 166866
An inhibitor for both ATP competitive pyrido [2,3-d]pyrimidine tyrosine kinase and for bFGF
192705-79-6 sc-208154
5 mg
$220.00
0
PDGFR Tyrosine Kinase Inhibitor VI, SU6668
A potent ATP-competitive inhibitor against tyrosine kinases
210644-62-5 sc-204175
5 mg
$79.00
9
PD 166285
An inhibitor of RTK, c-Src, FGFR1, Wee 1, and PDGFRβ
212391-63-4 sc-208153
5 mg
$100.00
1
VEGFR2 kinase inhibitor IV
An ATP-competitive VEGFR-2 (Flk-1) and PDGFR-beta inhibitor
216661-57-3 sc-204381
1 mg
$200.00
0
SU 16f
A potent PDGFRβ inhibitor
251356-45-3 sc-204307
sc-204307A
10 mg
50 mg
$209.00
$880.00
0
Pelitinib
An EGFR inhibitor
257933-82-7 sc-208155
5 mg
$350.00
0
VEGFR Tyrosine Kinase Inhibitor II
An agent that potently inhibits kinase activities of KDR, Flt-1 and c-Kit
269390-69-4 sc-204378
5 mg
$199.00
0
VEGFR Tyrosine Kinase Inhibitor III, KRN633
An ATP-competitive inhibitor of VEGFR (Flt and Flk) kinase
286370-15-8 sc-204379
1 mg
$170.00
2
VEGFR2 Kinase Inhibitor II
A cell permeable RTK inhibitor blocking VEGFR, FGFR, and PDGF activity.
288144-20-7 sc-204380
1 mg
$148.00
0
3-(4-Hydroxybenzylidenyl)shyindolin-2-one
A selective receptor tyrosine kinase (RTK) inhibitor shown to inhibit FLK-1 RTK
293302-14-4 sc-202412
sc-202412A
1 mg
5 mg
$55.00
$216.00
0
ZM 323881 hydrochloride
A receptor tyrosine kinase inhibitor of VEGFR-2 (Flk-1), PDGFR-beta, EGFR, and FGFR1
324077-30-7 sc-296861
sc-296861A
1 mg
10 mg
$105.00
$164.00
0
Tandutinib
A piperazinyl quinazoline receptor tyrosine kinase inhibitor
387867-13-2 sc-202353
sc-202353A
1 mg
5 mg
$80.00
$240.00
0
Bcr-abl Inhibitor
An inhibitor of c-Abl and Bcr-abl activity
778270-11-4 sc-203836
5 mg
$149.00
1
ABT-869
A VEGF (Flk/Flt) and PDGFR inhibitor
796967-16-3 sc-359037
sc-359037A
1 mg
5 mg
$122.00
$560.00
0
cFMS Receptor Tyrosine Kinase Inhibitor
A cFMS kinase activity inhibitor
870483-87-7 sc-203877
sc-203877A
1 mg
5 mg
$30.00
$52.00
0
EGFR Inhibitor
A highly selective, cell-permeable EGFR inhibitor
879127-07-8 sc-203934
1 mg
$99.00
0
4-Amino-1-tert-butyl-3-(3-methylbenzyl)shypyrazolo[3,4-d]pyrimidine
An inhibitor of v-Src tyrosine kinase
956025-83-5 sc-206805
10 mg
$280.00
0
Hymenialdisine Analogue 1
A potent inhibitor of a variety of kinases
693222-51-4 sc-280808
1 mg
$350.00
0
Tyrphostin AG 1007
sc-222380
sc-222380A
1 mg
5 mg
$35.00
$103.00
0
BPDQ
A potent, reversible, and specific inhibitor of EGFR tyrosine kinase
169205-87-2 sc-311299
1 mg
$160.00
0
VEGFR Tyrosine Kinase Inhibitor V
A potent antagonist of VEGFR activity and HUVEC proliferation
sc-356190
5 mg
$240.00
0
3-(3,5-Di-tert-butyl-4-hydroxybenzylidenyl)shyindolin-2-one
A receptor tyrosine kinase inhibitor
40526-64-5 sc-202015
sc-202015A
1 mg
5 mg
$35.00
$137.00
0
AG-1288
A tyrosine kinase inhibitor and cell protective agent
116313-73-6 sc-200664
sc-200664A
10 mg
50 mg
$58.00
$299.00
0
Tyrphostin 47
An inhibitor of EGFR tyrosine kinase
118409-60-2 sc-216031
5 mg
$64.00
0
Tyrphostin AG 528
An inhibitor of EGFR tyrosine kinase activity
133550-49-9 sc-216034
5 mg
$42.00
0
Phenethyl dimethyl caffeate
An inhibitor of protein tytosine kinase and ornithine decarboxylase
145551-14-0 sc-204841
sc-204841A
50 mg
100 mg
$58.00
$85.00
0
BPIQ-I
A potent and specific inhibitor of tyrosine kinase activity of EGFR
174709-30-9 sc-202507
1 mg
$150.00
0
4-Amino-1-tert-butyl-3-(3-benzyl)shypyrazolo[3,4-d]pyrimidine
A tyrosine kinase inhibitor
186895-85-2 sc-206804
10 mg
$280.00
0
PDGFR Tyrosine Kinase Inhibitor II
A cell-permeable isothiourea compound that perturbs MreB function
249762-74-1 sc-204172
1 mg
$232.00
0
3-(3-tert-Butyl-4-methoxybenzylidenyl)shyindolin-2-one
A selective receptor tyrosine kinase (RTK) inhibitor
293302-19-9 sc-202410
sc-202410A
1 mg
5 mg
$35.00
$137.00
0
Motesanib
An inhibitor of Flk-1, Flt-4, PDGFR-β and c-Kit.
453562-69-1 sc-391480
5 mg
$290.00
0
Syk Inhibitor IV, BAY 61-3606 HCl
An imidazopyrimidine inhibitor of Syk and Syk-mediated functions
732983-37-8 sc-202351
2 mg
$164.00
14
Dasatinib
A chemical directly targets wild-type and mutant c-Abl kinase domains
302962-49-8 sc-358114
sc-358114A
25 mg
1 g
$36.00
$132.00
19
A 83-01
An inhibitor of TGFβ-RI, ACTR-IB and ACTR-IC
909910-43-6 sc-203791
sc-203791A
10 mg
50 mg
$190.00
$772.00
5
Dasatinib (monohydrate)
An inhibitor of Src family kinases, including c-Abl and Bcr-Abl tyrosine kinase activity
863127-77-9 sc-218081
sc-218081A
10 mg
100 mg
$80.00
$300.00
6
AZD4547
A novel selective FGFR inhibitor targeting Flg (FGFR1), Bek (FGFR2), and FGFR-3
1035270-39-3 sc-364421
sc-364421A
5 mg
10 mg
$198.00
$309.00
2
Nilotinib
A rationally designed c-Abl and Bcr-Abl kinase inhibitor
641571-10-0 sc-202245
sc-202245A
10 mg
25 mg
$196.00
$395.00
4
AG 1024
Inhibits insulin-stimulated cellular proliferation and IGF-1R autophosphorylation
65678-07-1 sc-205907
1 mg
$74.00
13
Demethylasterriquinone B1
A cell-permeable insulin mimic that does not affect IGF-1R, EGFR, or PDGFR
78860-34-1 sc-203025
sc-203025A
5 mg
50 mg
$235.00
$800.00
2
FAK Inhibitor 14
A potent FAK inhibitor that demonstrates antiproliferative activity in several tumor cell lines
4506-66-5 sc-203950
sc-203950A
10 mg
50 mg
$100.00
$224.00
42
BML-267
A potent and selective protein tyrosine phosphatase 1B (PTP1B) inhibitor
sc-205605
sc-205605A
10 mg
50 mg
$79.00
$432.00
0
Geldanamycin
An inhibitor of HSP 90 and nuclear hormone receptor family
30562-34-6 sc-200617
sc-200617A
1 mg
5 mg
$89.00
$188.00
2
SU6656
A small-molecule inhibitor of potently and selectively inhibits Src tyrosine kinases
330161-87-0 sc-203286
sc-203286A
1 mg
5 mg
$50.00
$123.00
13
AGL 2263
A cell-permeable benzoxazolone-containing bioisostere of tyrphostin AG 538; acts as an inhibitor of insulin receptor
sc-221223
5 mg
$300.00
1
PD 161570
A selective FGFR inhibitor
192705-80-9 sc-361284
sc-361284A
5 mg
25 mg
$112.00
$446.00
0
Pazopanib
A potent and selective inhibitor of Flk-1, PDGFR and c-kit
444731-52-6 sc-396318
sc-396318A
25 mg
50 mg
$120.00
$170.00
0
Quercetin 3-Sulfate Potassium Salt
121241-74-5 sc-476449
500 µg
$300.00
0
Quercetin 3-O-beta-xyloside-d3
sc-476826
1 mg
$350.00
0
Src Kinase Inhibitor II
An inhibitor of Src family tyrosine kinases
sc-222325
5 mg
$338.00
0
Ste11 MAPKKK Activation Inhibitor
Reported to inhibit Ste 11 signalling and c-Abl Tyr kinase activity
331662-51-2 sc-355980
5 mg
$225.00
0
Phenylethyl 3-methylcaffeate
A chemopreventative and apoptosis amplifier
71835-85-3 sc-205804
sc-205804A
50 mg
100 mg
$100.00
$145.00
0
N,N-Dimethyl Sunitinib
An angiogenesis inhibitor
326914-17-4 sc-208065
1 mg
$548.00
0
N-Desmethyl Imatinib-d8
A deuterated metabolite of gleevec
404844-02-6 (unlabeled) sc-219123
sc-219123A
250 µg
2.5 mg
$500.00
$4,000.00
4
Genistein-2prime,6prime-d2
A labeled form of genistein
315204-48-9 sc-280729
1 mg
$220.00
0
Dasatinib-d8
A novel, small-molecule Tyrosine Kinase Inhibitor (TKI)
1132093-70-9 sc-218084
1 mg
$350.00
0
JNJ-38877605
An ATP-competitive inhibitor for the catalytic activity of Met
943540-75-8 sc-364516
sc-364516A
2 mg
10 mg
$126.00
$365.00
0
Genistein-2prime,3prime,5prime,6prime-d4
A protein kinase inhibitor
187960-08-3 sc-280728
1 mg
$280.00
0
3prime,4prime,5prime,5,7-Pentamethoxyflavanone
479672-30-5 sc-216630
10 mg
$220.00
0
Lapatinib-d7 Dihydrochloride
CAS: 1009307-23-6 (free base), MF: C29H19D7ClFN4O4S•2HCl, MW: 661.02
1009307-23-6 (free base) sc-488774
1 mg
$400.00
0
3-Methyl 7-Azaoxindole
1330055-85-0 sc-482877
50 mg
$300.00
0
Adaphostin
A Bcr-Abl (the fusion protein of Bcr and c-Abl) tyrosine kinase inhibitor
241127-58-2 sc-291833
sc-291833A
10 mg
50 mg
$129.00
$560.00
0
Imatinib-d8
A deuterated tyrosine kinase inhibitor.
1092942-82-9 sc-488072
sc-488072A
1 mg
10 mg
$500.00
$4,000.00
0

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