Topo II Inhibitors

Santa Cruz Biotechnology now offers a broad range of Topo II Inhibitors. DNA topoisomerase I and II (Topo I and Topo II) are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Topo II Inhibitors offered by Santa Cruz inhibit Topo II and, in some cases, other DNA replication and recombination related proteins. View detailed Topo II Inhibitor specifications, including Topo II Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/ApplicationCASCatalog #QUANTITYPriceCitationsRATING
Podophyllotoxin
A potent inhibitor of microtubule assembly and DNA topoisomerase II
518-28-5sc-204853
100 mg
$26.00
0
Doxorubicin hydrochloride
A Topo II inhibitor, DNA intercalator and powerful cytotoxic agent
25316-40-9sc-200923
sc-200923B
sc-200923A
5 mg
10 mg
25 mg
$77.00
$140.00
$309.00
14
Arctigenin
A dibenzyl butyrolactone lignan with antiinflammatory and antioxidant properties
7770-78-7sc-202957
25 mg
$79.00
10
Suramin sodium
A G protein uncoupler and inhibitor of PDGF, EGF, TGFb, SIRT1 and SIRT5
129-46-4sc-200833
sc-200833A
sc-200833B
50 mg
250 mg
1 g
$36.00
$143.00
$540.00
6
Staurosporine
An antifungal inhibitor of many different enzymes
62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$75.00
$140.00
$380.00
49
Ciprofloxacin HCl
A DNA gyrase/topoisomerase-targeting antibiotic often used in cell culture
93107-08-5sc-29064
sc-29064A
1 g
5 g
$75.00
$170.00
15
Etoposide (VP-16)
Inhibits DNA synthesis via topoisomerase II inhibition
33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$25.00
$154.00
$325.00
25
Genistein
A highly specific inhibitor of protein tyrosine kinase (PTK)
446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$25.00
$90.00
$118.00
$304.00
$490.00
$890.00
$1,785.00
20
Oxolinic Acid
A quinoline antibacterial compound and inhibitor of Topo II
14698-29-4sc-212488
1 g
$30.00
0
Ellipticine
A DNA intercalating inhibitor of Topo II
519-23-3sc-200878
sc-200878A
10 mg
50 mg
$104.00
$430.00
1
3-O-Acetyl-beta-boswellic acid
A non-competitive 5-lipoxygenase and topoisomerase I and IIa
5968-70-7sc-202885
sc-202885A
1 mg
5 mg
$55.00
$123.00
0
Sedanolide
An inducer of GST and inhibitor of Cox-1, Cox-2, Topo I, Topo II, and carcinogenesis
6415-59-4sc-205972
100 mg
$148.00
0
(-)-Arctiin
A lignan derivative that downregulates Bcl-XL and inhibits HIV-1 integrase
20362-31-6sc-202064
25 mg
$62.00
1
9-Hydroxyellipticine, Hydrochloride
A potent topoisomerase II inhibitor
52238-35-4sc-203940
sc-203940A
10 mg
50 mg
$220.00
$700.00
0
Mitoxantrone Dihydrochloride
Induces DNA damage by intercalating into DNA and inhibiting Topo II
70476-82-3sc-203136
sc-203136A
10 mg
50 mg
$31.00
$57.00
4
Celastrol, Celastrus scandens
An antiproliferative, antipreroxidative, and inhibits Topo II
34157-83-0sc-202534
10 mg
$152.00
5
Garenoxacin-d4
A labeled antibacterial
sc-218564
10 mg
$11,000.00
0
Clinafloxacin
A fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV
105956-97-6sc-202107
250 mg
$400.00
1
Acetyl-11-keto-beta-Boswellic Acid, Boswellia serrata
A 5-LO and topo I and II inhibitor
67416-61-9sc-221208
5 mg
$145.00
0
Daunorubicin hydrochloride
A DNA intercalator which may suppress acute leukemia proliferation
23541-50-6sc-200921
sc-200921A
10 mg
50 mg
$96.00
$416.00
2
Epirubicin Hydrochloride
A cell-permeable Topo II inhibitor
56390-09-1sc-203041
5 mg
$147.00
0
Mitoxantrone
A type II topoisomerase inhibitor
65271-80-9sc-207888
100 mg
$188.00
3
Gatifloxacin
A fluoroquinolone antibiotic and inhibitor of type II bacterial topoisomerases
112811-59-3sc-204762
sc-204762A
1 g
5 g
$60.00
$260.00
13
HU-331
A hydroxylquinone cannabidiol analog
137252-25-6sc-205345
sc-205345A
1 mg
5 mg
$98.00
$800.00
1
Moxifloxacin Hydrochloride
An antibacterial agent that inhibits the activities of Topo II (DNA gyrase) and topoisomerase IV
186826-86-8sc-205758
sc-205758A
100 mg
500 mg
$116.00
$440.00
9
Novobiocin Sodium Salt
An Hsp90 and DNA gyrase inhibitor
1476-53-5sc-358734
sc-358734A
1 g
5 g
$55.00
$190.00
0
Chartreusin
An antiproliferative agent that inhibits topoisomerase II
6377-18-0sc-202994
sc-202994A
5 mg
25 mg
$105.00
$615.00
0
Razoxane
An inhibitor of Topo II
21416-67-1sc-253425
sc-253425A
5 mg
25 mg
$72.00
$288.00
0
Dexrazoxane
An inhibitor of Topo II
24584-09-6sc-252669
5 mg
$70.00
0
Cinoxacin
An antibacterial quinolone
28657-80-9sc-202543
sc-202543A
50 mg
250 mg
$20.00
$35.00
0
Teniposide
A derivative of podophyllotoxin that has shown cytostatic effect & inhibition of topoisomerase II
29767-20-2sc-204910
sc-204910A
25 mg
100 mg
$71.00
$225.00
2
Amonafide
A DNA intercalator and topoisomerase II inhibitor
69408-81-7sc-207283
10 mg
$216.00
0
Pirarubicin
An anti-neoplastic and inhibitor of Topo II
72496-41-4sc-205810
sc-205810A
5 mg
10 mg
$170.00
$300.00
0
O-Deacetylravidomycin
A more active and stable analogue of the ravidomycin complex
88580-27-2sc-202253
500 µg
$288.00
0
Lemofloxacin
98079-51-7sc-279272
100 mg
$250.00
1
Lomefloxacin, Hydrochloride
A Topo II antagonist
98079-52-8sc-218660
1 g
$53.00
0
Difloxacin hydrochloride
An antimicrobial quinolone antibiotic
91296-86-5sc-205648
sc-205648A
5 g
25 g
$186.00
$829.00
0
Amrubicin
An inhibitor of DNA topoisomerase II
110267-81-7sc-207289
5 mg
$1,000.00
1
Sparfloxacin
A broad spectrum fluoroquinolone antibiotic
110871-86-8sc-202343
sc-202343A
1 g
5 g
$44.00
$107.00
0
Danofloxacin-d3 Mesylate
A labeled fluorinated quinolone antibacterial compound
119478-55-6 (unlabeled)sc-218069
1 mg
$300.00
0
Becatecarin
A semisynthetic water soluble derivative of rebeccamycin
119673-08-4sc-202493
sc-202493A
250 µg
1 mg
$340.00
$982.00
0
Prulifloxacin
A compound with broad spectrum antibacterial activity
123447-62-1sc-204868
sc-204868A
250 mg
1 g
$74.00
$400.00
0
Nadifloxacin
A fluoroquinolone broad spectrum antibiotic
124858-35-1sc-202723
sc-202723A
250 mg
1 g
$104.00
$304.00
1
Levofloxacin hydrochloride
A fluoroquinolone antibiotic inhibitor of DNA gyrase and topoisomerase IV
177325-13-2sc-202693
sc-202693A
1 g
5 g
$33.00
$77.00
1
Lucanthone Hydrochloride
A Topoisomerase II inhibitor
548-57-2sc-396381
sc-396381A
10 mg
5 mg
$280.00
$140.00
0
Epirubicin
A cell permeable Topo II inhibitor
56420-45-2sc-279016
25 mg
$450.00
0
Amonafide-d6
A Topo II inhibitor and an antitumor agent
69408-81-7 (unlabeled)sc-217636
1 mg
$280.00
0
Etoposide Phosphate
A topoisomerase II inhibitor inspired by podophyllotoxin
117091-64-2sc-357357
sc-357357A
25 mg
100 mg
$135.00
$350.00
2
Doxorubicin
An immunosuppresive antineoplastic antibiotic
23214-92-8sc-280681
1 mg
$160.00
13
Chrysomycin A
A potent antibacterial, antifungal and antiviral compound
82196-88-1sc-202099
sc-202099A
250 µg
1 mg
$325.00
$1,060.00
0
Chrysomycin B
An inhibitor of the catalytic activity of human topoisomerase II
83852-56-6sc-202100
sc-202100A
250 µg
1 mg
$142.00
$420.00
0
UK-1
An antibiotic and antifungal inhibitor of topoisomerase II
151271-53-3sc-202849
sc-202849A
250 µg
1 mg
$142.00
$420.00
0
Fleroxacin
An antiproliferative antibacterial agent
79660-72-3sc-205694
sc-205694A
5 g
10 g
$192.00
$360.00
0
Amsacrine hydrochloride
An inhibitor of DNA topoisomerase II
54301-15-4sc-214540
10 mg
$232.00
0
Norfloxacin
A fluorinated quinolone antibacterial agent
70458-96-7sc-215586
10 g
$116.00
0
Garenoxacin
An antibacterial agent and a Topo II inhibitor
194804-75-6sc-490878
25 mg
$300.00
0
Merbarone
97534-21-9sc-500526
25 mg
$121.00
0
Etoposide-d3
The labeled form of Etoposide
sc-218445
1 mg
$350.00
6
alpha-Etoposide
A cytotoxic agent
100007-53-2sc-497424
2.5 mg
$350.00
0
Levofloxacin
An antibiotic compound
100986-85-4sc-252953
sc-252953A
sc-252953B
10 mg
1 g
250 mg
$35.00
$39.00
$37.00
0
Bis(cyclopentadienyl)vanadium(IV) dichloride
A useful catalyst
12083-48-6sc-227388
1 g
$58.00
0
Protocatechuic acid ethyl ester
An antioxidant
3943-89-3sc-236496
5 g
$32.00
0
Sobuzoxane
An inhibitor of DNA topoisomerase II which induces apoptosis
98631-95-9sc-215862
sc-215862A
sc-215862B
sc-215862C
5 mg
25 mg
50 mg
100 mg
$178.00
$670.00
$940.00
$1,313.00
0
Fostriecin
A Topo II, PP1, and PP2A inhibitor
87860-39-7sc-202160
50 µg
$245.00
6

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