Topo I Inhibitors

Santa Cruz Biotechnology now offers a broad range of Topo I Inhibitors. DNA topoisomerase I and II (Topo I and Topo II) are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Topo I Inhibitors offered by Santa Cruz inhibit Topo I and, in some cases, other DNA replication and recombination related proteins. View detailed Topo I Inhibitor specifications, including Topo I Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/ApplicationCASCatalog #QUANTITYPriceCitationsRATING
Suramin sodium
A G protein uncoupler and inhibitor of PDGF, EGF, TGFb, SIRT1 and SIRT5
129-46-4sc-200833
sc-200833A
sc-200833B
50 mg
250 mg
1 g
$36.00
$143.00
$540.00
6
beta-Lapachone
A selective DNA topoisomerase I inhibitor
4707-32-8sc-200875
sc-200875A
5 mg
25 mg
$77.00
$324.00
6
SN 38
The active metabolite of the topoisomerase-I (topo-I) inhibitor Irinotecan (CPT-11)
86639-52-3sc-203697
sc-203697A
sc-203697B
10 mg
50 mg
500 mg
$109.00
$323.00
$860.00
6
NU 1025
A potent PARP-1 and Topo I inhibitor
90417-38-2sc-203166
5 mg
$131.00
6
Ellagic Acid, Dihydrate
A CK2, Topo I and II, FGR, GSK, and PKA inhibitor
314041-08-2sc-202598
sc-202598A
500 mg
5 g
$50.00
$85.00
0
Luteolin
An inhibitor of glutathione S-transferase and 15-LO
491-70-3sc-203119
sc-203119A
sc-203119B
sc-203119C
sc-203119D
5 mg
50 mg
500 mg
5 g
500 g
$20.00
$25.00
$60.00
$80.00
$1,850.00
7
3-O-Acetyl-beta-boswellic acid
A non-competitive 5-lipoxygenase and topoisomerase I and IIa
5968-70-7sc-202885
sc-202885A
1 mg
5 mg
$55.00
$123.00
0
Sedanolide
An inducer of GST and inhibitor of Cox-1, Cox-2, Topo I, Topo II, and carcinogenesis
6415-59-4sc-205972
100 mg
$148.00
0
(S)-10-Hydroxycamptothecin
A camptothecin derivative that inhibits DNA topoisomerase I
19685-09-7sc-205614
sc-205614A
25 mg
100 mg
$58.00
$165.00
1
Irinotecan-d10 Hydrochloride
A deuterated DNA Topo I inhibitor
718612-62-5sc-280849
sc-280849A
1 mg
10 mg
$250.00
$2,000.00
7
Topotecan Hydrochloride
A water-soluble inhibitor of DNA Topo I
119413-54-6sc-204919
sc-204919A
1 mg
5 mg
$34.00
$93.00
0
Acetyl-11-keto-beta-Boswellic Acid, Boswellia serrata
A 5-LO and topo I and II inhibitor
67416-61-9sc-221208
5 mg
$145.00
0
Daunorubicin hydrochloride
A DNA intercalator which may suppress acute leukemia proliferation
23541-50-6sc-200921
sc-200921A
10 mg
50 mg
$96.00
$416.00
2
Rebeccamycin
An indolocarbazole topoisomerase inhibitor
93908-02-2sc-202309
sc-202309A
250 µg
1 mg
$83.00
$300.00
0
Irinotecan hydrochloride trihydrate
An inhibitor of Topo I
136572-09-3sc-202186
sc-202186A
5 mg
25 mg
$93.00
$341.00
6
Rubitecan
A DNA topoisomerase I inhibitor
91421-42-0sc-219998
10 mg
$40.00
0
Irinotecan Carboxylate Sodium Salt
A carboxylated Topo I inhibitor
sc-280848
5 mg
$280.00
0
Thiocolchicine
A specific tubulin synthesis inhibitor and Topo I inhibitor
2730-71-4sc-202838
sc-202838A
100 mg
5 mg
$194.00
$125.00
0
7-Ethyl Camptothecin
An anti-cancer agent and Topo I inhibitor
78287-27-1sc-207171
10 mg
$188.00
0
9-Aminocamptothecin
An active derivative of camptothecin and topoisomerase inhibitor
91421-43-1sc-205615
sc-205615A
10 mg
25 mg
$160.00
$331.00
1
(+)-Irinotecan
A Topo I inhibitor
97682-44-5sc-269253
10 mg
$60.00
0
Topotecan
A topo I inhibitor shown to stabilize topo I/DNA cleavable complexes
123948-87-8sc-338718
100 mg
$560.00
0
Reticulol
An isocoumarin metabolite shown to inactivate topoisomerase I
26246-41-3sc-202313
sc-202313A
250 µg
1 mg
$100.00
$213.00
0
Sodium Camptothecin
The salt form of Camptothecin
25387-67-1sc-338592
1 g
$700.00
0
7-Ethyl-d3-camptothecin
A deuterium labeled Topo I inhibitor
78287-27-1 (unlabeled)sc-217437
1 mg
$450.00
0
Irinotecan Labeled d10
A deuterated DNA Topo I inhibitor
97682-44-5 (unlabeled)sc-353632
10 mg
$2,540.00
0
Topotecan Hydrochloride Labeled d6
An isotope labeled Topo I inhibitor
119413-54-6 (unlabeled)sc-356167
10 mg
$2,000.00
0
11-Ethyl Camptothecin
A substituted Topo I inhibitor
185807-29-8sc-213584
10 mg
$31,500.00
0
Genz 644282
A topoisomerase I inhibitor
529488-28-6sc-396035
5 mg
$155.00
0
(R)-7-Ethyl Camptothecin
A R-Camptothecin derivative and Topo I inhibitor
1217633-65-2sc-219741
1 mg
$280.00
0
Topotecan-d6
A labeled DNA topoisomerase I inhibitor
123948-87-8 (unlabeled)sc-220273
1 mg
$300.00
0
2prime,3prime-Dideoxyadenosine-5prime-triphosphate Lithium Salt
93939-70-9sc-288569
sc-288569A
1 mg
5 mg
$237.00
$945.00
0

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