TS Inhibitors

Thymidylate synthase (TS), also designated TYMS, TMS, TSase and HsT422, uses 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor in the synthesis of 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor for DNA biosynthesis. Biochemicals that inhibit TS have many applications in biochemical and physiological research. Click on the product name to view detailed information such as the chemical structure and specific chemical properties for each of our TS Inhibitors. In stock TS Inhibitors are available for immediate shipping.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
5-Fluoro-2prime-deoxyuridine
An experimental antiproliferative agent shown to have activity against variety of neoplasms
50-91-9 sc-202425
50 mg
$76.00
0
5-Fluorouracil-6-d1
A potent antineoplastic agent which inhibits TS and DNA synthesis
90344-84-6 sc-207031
sc-207031A
5 mg
50 mg
$300.00
$2,400.00
0
Capecitabine-d11
An isotopically labelled antineoplastic agent
1132662-08-8 sc-207398
1 mg
$263.00
5
Nolatrexed Dihydrochloride
An inhibitor of thymidylate synthase
152946-68-4 sc-208103
10 mg
$220.00
0
Pemetrexed Disodium
An inhibitor of TS, DHFR and GARFT
150399-23-8 sc-219564
10 mg
$125.00
2
Pemetrexed-d5 Disodium Salt
An isotope labeled antineoplastic multitargeted antifolate
150399-23-8 (unlabeled) sc-219565
sc-219565A
1 mg
10 mg
$298.00
$2,800.00
0
Raltitrexed
An inhibitor of thymidylate synthase and DHFR
112887-68-0 sc-219933
10 mg
$167.00
0
Trifluorothymidine
A substrate used to study the specificity and kinetics of thymidine kinases
70-00-8 sc-222370
sc-222370A
100 mg
1 g
$179.00
$500.00
1
Fluorouracil
A DNA synthesis blocker which arrests the cell cycle in G2
51-21-8 sc-29060
sc-29060A
1 g
5 g
$30.00
$141.00
8
Methotrexate
A cell cycle arresting agent that inhibits DHFR
59-05-2 sc-3507
sc-3507A
100 mg
500 mg
$79.00
$195.00
20

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