Phosphatases and Phosphatase Activators and Inhibitors

Santa Cruz Biotechnology now offers a broad range of Phosphatases and Phosphatase Activators and Inhibitors. Phosphatases are enzymes that remove phosphate from a substrate resulting in a phosphate ion and a hydroxyl group on the substrate. Since phosphorylation and dephosphorylation often activate or deactivate a protein, phosphatase and its activators and inhibitors are an integral part in cell signaling. Our popular products such as Phosphatase Inhibitor Cocktail A, Phosphatase Inhibitor Cocktail A, and Salubrinal are typically available for immediate shipment.

indicates a highly recommended product based on customer preference.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Phosphatase Inhibitor Cocktail A
An inhibitor of L-isozymes of alkaline phosphatase and ser/thr protein phosphatases
sc-45044
1 ml
$54.00
27
Okadaic Acid
An activator of PKC and inhibitor of PP1 and PP2A phosphatases
78111-17-8 sc-3513
sc-3513A
25 µg
100 µg
$75.00
$200.00
37
Phosphatase Inhibitor Cocktail C
An inhibitor of alkaline and ser/thr phosphatases used for research purposes
sc-45065
1 ml
$89.00
13
Calyculin A
A PP1 and PP2A-C inhibitor and tumor inducer
101932-71-2 sc-24000
sc-24000A
sc-24000B
sc-24000C
10 µg
100 µg
500 µg
1 mg
$55.00
$331.00
$1,365.00
$2,500.00
23
Salubrinal
A selective inhibitor of eIF-2α used to study ER stress-induced apoptosis
405060-95-9 sc-202332
sc-202332A
1 mg
5 mg
$32.00
$100.00
51
bpV(HOpic)
A protein PTP inhibitor
722494-26-0 sc-221377
5 mg
$88.00
4
bpV(pic)
A potent protein PTP inhibitor
148556-27-8 sc-221379
sc-221379A
5 mg
25 mg
$84.00
$321.00
8
alpha-Naphthyl Acid Phosphate Monosodium Salt
A non-specific phosphatase inhibitor
81012-89-7 sc-202898
5 g
$63.00
0
beta-Glycerophosphate disodium salt pentahydrate
A potent phosphatase inhibitor
13408-09-8 sc-203323
sc-203323A
50 g
100 g
$50.00
$102.00
5
Tautomycin
A potent and specific PP1 and PP2 inhibitor
109946-35-2 sc-200587
25 µg
$200.00
5
Ceramide C6
An ERK activator which arrests cells at the G0/G1 phase
124753-97-5 sc-3527
sc-3527A
5 mg
25 mg
$80.00
$230.00
16
C2 Ceramide
A ser/thr protein phosphatase activator
3102-57-6 sc-201375
sc-201375A
5 mg
25 mg
$57.00
$217.00
3
Cypermethrin, solid
A potent inhibitor of calcineurin
52315-07-8 sc-24012
10 mg
$35.00
10
bpV(phen)
An insulin mimetic shown to inhibit the dephosphorylation of insulin receptors
42494-73-5 sc-221378
sc-221378A
5 mg
25 mg
$94.00
$280.00
7
Okadaic acid sodium salt
A naturally occurring inhibitor of PP1A and PP2A/PP2B
209266-80-8 sc-202259
sc-202259A
sc-202259B
25 µg
100 µg
1 mg
$62.00
$142.00
$1,215.00
2
Cantharidin
A toxic herbicidal potent inhibitor of PP2A phosphatase activity
56-25-7 sc-201321
sc-201321A
25 mg
100 mg
$63.00
$134.00
4
PTP Inhibitor I
A potent covalent inhibitor of protein tyrosine phosphatases SHP-1 and PTPIB
2491-38-5 sc-204220
sc-204220A
10 mg
100 mg
$100.00
$200.00
4
PTP Inhibitor III
A cell-permeable compound that inhibits a broad-range of PTPs
29936-81-0 sc-222224
10 mg
$270.00
7
O-3M3FBS
A negative control inactive analog of m-3M3FBS
313981-55-4 sc-204142
sc-204142A
10 mg
50 mg
$129.00
$450.00
0
CinnGEL 2-methylester
A cell-permeable PTP1B inhibitor
sc-205633
1 mg
$140.00
2
HELSS (Haloenol lactone suicide substrate, BEL, Bromoenol lactone)
An inhibitor of Ca-independent PLA2 and Mg-dependent PAP
88070-98-8 sc-201418
sc-201418A
5 mg
25 mg
$145.00
$490.00
7
L-p-Bromotetramisole oxalate
A non-specific alkaline phosphatase inhibitor
62284-79-1 sc-201431
sc-201431A
sc-201431B
sc-201431C
5 mg
50 mg
100 mg
1 g
$64.00
$354.00
$500.00
$3,500.00
0
E6 Berbamine
A selective and cell-permeable CaM antagonist
73885-53-7 sc-221573
sc-221573A
10 mg
50 mg
$109.00
$450.00
1
PTP CD45 Inhibitor
A cell permeable potent reversible inhibitor of CD45
345630-40-2 sc-222223
5 mg
$288.00
1
Endothall
An herbicidal inhibitor of PP2A phosphatase activity
145-73-3 sc-201325
sc-201325A
20 mg
100 mg
$37.00
$155.00
0
Beryllium fluoride
A chemical used in protein crystallography as a mimic of phosphate. ADP and beryllium fluoride together tend to bind to ATP sites and inhibit protein action, making it possible to crystallise proteins in the bound state. Principal precursor for the manufa
7787-49-7 sc-263025
5 g
$210.00
0
7-(beta-Hydroxyethyl)-theophylline
A weak phosphodiesterase inhibitor & an intermediate for 7-substituted xanthine
519-37-9 sc-202836
5 g
$30.00
1
Sodium Fluoride
An inhibitor of serine/threonine phosphatases widely used in bone and dental research
7681-49-4 sc-24988
sc-24988A
sc-24988B
100 g
5 g
500 g
$39.00
$33.00
$91.00
18
C16 Ceramide (N-Palmitoylsphingosine, D-erythro)
An endogenous ceramide
24696-26-2 sc-201379
sc-201379A
5 mg
25 mg
$67.00
$284.00
1
CDC25 Phosphatase Inhibitor II, NSC 663284
A competitive CDC25 inhibitor and cell cycle arresting compound
383907-43-5 sc-202987
5 mg
$155.00
1
PRL-3 Inhibitor
A cell permeable benzylidene rhodanine compound
893449-38-2 sc-222189
10 mg
$280.00
1
Dephostatin
A competitive protein-tyrosine phosphatase inhibitor
151606-30-3 sc-202131
1 mg
$136.00
8
3,4-Dephostatin
A protein tyrosine phosphatase inhibitor
sc-220885
1 mg
$152.00
0
AACOCH3
A negative control for AACOCF31,2 and stimulator of AA release
sc-205590
sc-205590A
10 mg
50 mg
$53.00
$285.00
0
Phorbol-12,13-dibutyrate
A protein kinase C activator
37558-16-0 sc-202285
1 mg
$115.00
1
Anagrelide hydrochloride
A potent type III phosphodiesterase inhibitor
58579-51-4 sc-203513
sc-203513A
10 mg
50 mg
$101.00
$575.00
1
eIF-2alpha Inhibitor II, Sal003
A potent cell-permeable analog of the eIF2α phosphatase inhibitor Salubrinal
1164470-53-4 sc-221582
5 mg
$130.00
1
bpV(bipy) trihydrate
A phosphotyrosine phosphatase and PTEN inhibitor and IRK activator
sc-311300
5 mg
$175.00
1
DL-erythro-Dihydrosphingosine
An inhibitor of PKC and PLA2
3102-56-5 sc-203018
sc-203018A
10 mg
100 mg
$97.00
$1,000.00
0
Cantharidic Acid
A potent and selective inhibitor of PP2A and PP1
28874-45-5 sc-201323
sc-201323A
10 mg
50 mg
$65.00
$240.00
0
Fenvalerate
A potent inhibitor of calcineurin with suggested activity at GABA receptors and other neuronal activity
51630-58-1 sc-24014
sc-24014A
25 mg
100 mg
$76.00
$222.00
3
5-Bromo-6-chloro-3-indolyl phosphate, p-toluidine salt
A staining substance for alkaline phosphatase activity
6769-80-8 sc-221017
sc-221017A
100 mg
250 mg
$188.00
$350.00
0
NSC 95397
A quinone-based Cdc25 inhibitor, caspase-3 activator, ERK activator, and MKP inhibitor
93718-83-3 sc-203654
sc-203654A
10 mg
50 mg
$175.00
$739.00
4
mpV(pic)
A protein phosphotyrosine phosphatase inhibitor
sc-221958
10 mg
$240.00
0
4-Aminophenylphosphate sodium salt
A substrate for the electrochemical measurement of alkaline phosphatase
sc-220931
10 mg
$33.00
0
PTP Inhibitor IV
A potent, reversible, competitive, & active-site directed inhibitor of PTP
329317-98-8 sc-222225
10 mg
$170.00
2
Ethyl-3,4-Dephostatin
A potent inhibitor of protein tyrosine phosphatase 1B
sc-220886
1 mg
$152.00
1
bpV(bipy)
A protein phosphotyrosine phosphatase inhibitor
sc-221376
sc-221376A
5 mg
25 mg
$120.00
$216.00
0
RWJ-60475-(AM)3
A cell-permeable acetoxymethyl (AM) ester of RWJ-60475
sc-222267
1 mg
$155.00
0
PTP Inhibitor II
A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor
2632-13-5 sc-202784
5 g
$48.00
0
Sodium stibogluconate
A robust inhibitor of PTPases, including PTPase1 (SHP-1), SHP-2, and PTP1B
16037-91-5 sc-202815
1 g
$180.00
3
ICI 63197
An inhibitor of phosphodiesterase 4 competitive with rolipram
27277-00-5 sc-203600
sc-203600A
10 mg
50 mg
$140.00
$575.00
0
BVT 948
A non-competitive protein tyrosine phosphatase inhibitor
39674-97-0 sc-203536
sc-203536A
10 mg
50 mg
$155.00
$650.00
0
Ibudilast
A nonselective phosphodiesterase inhibitor
50847-11-5 sc-203080
10 mg
$210.00
1
CaMKP Inhibitor Inhibitor
An amino-naphthol sulfonic acid that acts as a competitive substrate inhibitor of Ca2+/CaMKP
52789-62-5 sc-203866
25 g
$198.00
0
Deltamethrin
A Type II pyrethroid insecticide that potently inhibits calcineurin
52918-63-5 sc-24013
sc-24013A
10 mg
50 mg
$62.00
$259.00
9
W-5
A CaM antagonist that inhibits Ca2+/calmodulin- regulated activities
61714-25-8 sc-201500
25 mg
$131.00
2
Thielavin A
Apotent prostaglandin synthetase inhibitor
71950-66-8 sc-202361
500 µg
$298.00
0
Thielavin B
An inhibitor peptidoglycan formation, prostaglandin biosynthesis, and PLC
71950-67-9 sc-202362
500 µg
$307.00
0
Rp-Adenosine 3prime,5prime-cyclic Monophosphorothioate, Sodium Salt
A PKA inhibitor
73208-40-9 sc-202038
1 mg
$182.00
1
8-Methoxymethyl-IBMX
A Cam-PDE selective inhibitor
78033-08-6 sc-201192
sc-201192A
10 mg
50 mg
$169.00
$715.00
0
Methyl Okadaate
A Serine/Threonine protein phosphatase inhibitor
78111-14-5 sc-295454
100 µg
$435.00
0
Oleyloxyethyl Phosphorylcholine
A potent inhibitor of PLA2
96720-06-8 sc-200711
sc-200711A
10 mg
50 mg
$71.00
$266.00
5
RK-682, Streptomyces sp.
An effective tyrosine phosphatase inhibitor
154639-24-4 sc-202791
200 µg
$107.00
0
Okadaic Acid, Ammonium Salt
A protein phosphatase regulator
155716-06-6 sc-202260
25 µg
$62.00
10
CGH 2466
An Adenosine A1-R, Adenosine A2B-R, Adenosine A3-R, and p38 inhibitor
1177618-54-0 sc-203541
sc-203541A
10 mg
50 mg
$129.00
$548.00
0
Lambda Phosphatase
sc-200312A
sc-200312
20,000 units
100,000 units in 0.25ml
$118.00
$470.00
14
p38 MAP Kinase Inhibitor V
A cell-permeable highly potent ATP-competitive inhibitor of CK1 and p38
271576-77-3 sc-204160
1 mg
$338.00
0
C2 Phytoceramide
A ceramide-activated protein phosphatase (CAPP) activator
475995-69-8 sc-223853
sc-223853A
1 mg
5 mg
$59.00
$245.00
0
PTP1B Inhibitor
A protein tyrosine phosphatase 1B enzyme inhibitor
765317-72-4 sc-222227
5 mg
$220.00
6
Bacimethrin
An antibacterial agent and thiamine antagonist
3690-12-8 sc-364104
sc-364104A
500 µg
1 mg
$167.00
$294.00
0
Permethrin
A pyrethroid sodium channel modifier
52645-53-1 sc-201319
sc-201319A
10 mg
250 mg
$15.00
$35.00
0
1,4-Dimethylendothall
An endothall analog with no PP2A inhibition activity
109282-27-1 sc-201327
sc-201327A
10 mg
50 mg
$200.00
$400.00
0
Artesunate
A derivative of artemisinin
88495-63-0 sc-201329
sc-201329A
10 mg
50 mg
$60.00
$276.00
1
Phosphatase Inhibitor Cocktail B
An inhibitor of PTP-ases as well as acid and alkaline phosphatases
sc-45045
1 vial
$49.00
26
Resmethrin
A neural Ca2+-calmodulin-dependent protein phosphatase inhibitor
10453-86-8 sc-202312
sc-202312A
10 mg
25 mg
$20.00
$35.00
0
RK-682
A specific PTP1B inhibitor
332131-32-5 sc-202319
sc-202319A
200 µg
1 mg
$107.00
$446.00
4
Sodium Orthovanadate
An inhibitor of several phosphatases and kinases
13721-39-6 sc-3540
sc-3540A
5 g
50 g
$19.00
$95.00
92
NSC 87877
A potent inhibitor of shp2 and shp1 protein tyrosine phosphatases
56990-57-9 sc-204139
50 mg
$125.00
4
Alexidine dihydrochloride
An antibacterial and anti-plaque agent
1715-30-6 sc-210775
sc-210775A
1 g
100 mg
$360.00
$106.00
2
Benzylphosphonic Acid
A protein tyrosine phosphatase inhibitor
6881-57-8 sc-200588
sc-200588A
100 mg
500 mg
$30.00
$50.00
0
Benzylphosphonic Acid-(AM)2
A cell permeablederivative of benzylphosphonic acid
200716-68-3 sc-221349
sc-221349A
10 mg
50 mg
$67.00
$276.00
0
Caged Ins(1,4,5)P3, Trisodium Salt
A photo-activated derivative of Ins(1,4,5)P3
sc-221392
10 µg
$259.00
0
MBCQ
A selective inhibitor of cGMP-specific phosphodiesterase
150450-53-6 sc-221874
sc-221874A
5 mg
25 mg
$74.00
$224.00
0
Suramin sodium
A G protein uncoupler and inhibitor of PDGF, EGF, TGFb, SIRT1 and SIRT5
129-46-4 sc-200833
sc-200833A
sc-200833B
50 mg
250 mg
1 g
$36.00
$143.00
$540.00
6
Bakuchiol
A PTP1B and DNA polymerase inhibitor
10309-37-2 sc-202075
1 mg
$45.00
1
Calpeptin
A calpain-2, cathepsin L, and calpain-1 inhibitor
117591-20-5 sc-202516
sc-202516A
10 mg
50 mg
$107.00
$428.00
13
Ursodeoxycholic Acid, Sodium Salt
A steroid which reduces hydrophobic bile acids
2898-95-5 sc-222407
1 g
$400.00
1
TCS 401
A selective inhibitor of protein-tyrosine phosphatase 1B
243966-09-8 sc-204327
10 mg
$199.00
0
p-Nitrophenyl Phosphate 50X solution
A 50X liquid alkaline phosphatase substrate used in ELISA applications
sc-358718
10 ml
$218.00
0
BML-267
A potent and selective protein tyrosine phosphatase 1B (PTP1B) inhibitor
sc-205605
sc-205605A
10 mg
50 mg
$79.00
$432.00
0
Alexidine-d10 Dihydrochloride
1246818-47-2 sc-217597
sc-217597D
sc-217597A
sc-217597B
sc-217597C
1 mg
5 mg
10 mg
25 mg
100 mg
$200.00
$1,120.00
$2,250.00
$5,600.00
$13,400.00
0
PTP1B Substrate
A synthetic substrate for PTP1B
sc-3126
0.5 mg
$89.00
3
Alkaline Phosphatase (AP)
A high activity grade enzyme that can be used for antibody and protein conjugation
9001-78-9 sc-3716
sc-3716A
1 mg
5 mg
$50.00
$200.00
1
RWJ-60475
A non cell permeable inhibitor of the CD45 tyrosine phosphatase
204130-08-5 sc-222266
sc-222266A
5 mg
25 mg
$150.00
$650.00
0
Saccharin Sodium Salt
An inhibitor of the phosphotransferase and phosphohydrolase activities of glucose-6-phosphatase.
128-44-9 sc-296367
sc-296367A
100 g
500 g
$62.00
$136.00
0

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