PDE Inhibitors

Santa Cruz Biotechnology now offers a broad range of PDE Inhibitors. Phosphodiesterases (PDEs) are important regulators of signal transduction by facilitating the degradation of the cyclic nucleotide secondary messengers cAMP and cGMP. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation. View detailed PDE Inhibitor specifications, including PDE Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/ApplicationCASCatalog #QUANTITYPriceCitationsRATING
Ketotifen fumarate
A histamine H1 antagonist and mast cell growth inhibitor
34580-14-8sc-201094
sc-201094A
1 g
100 mg
$62.00
$39.00
0
BRL-50481
A selective inhibitor of PDE 7
433695-36-4sc-201178
sc-201178A
10 mg
50 mg
$72.00
$272.00
1
Caffeine
An adenosine receptor antagonist and cAMP phosphodiesterase inhibitor
58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
5 g
100 g
250 g
1 kg
5 kg
$20.00
$37.00
$55.00
$150.00
$700.00
8
Vardenafil-d5
A detuerium-labeled phosphodiesterase inhibitor
1189685-70-8sc-220369
1 mg
$280.00
0
Roflumilast
A selective inhibitor of phosphodiesterase 4
162401-32-3sc-208313
5 mg
$52.00
18
IBMX
A potent inhibitor of phosphodiesterases
28822-58-4sc-201188
sc-201188A
200 mg
1 g
$55.00
$155.00
9
Furafylline
An inhibitor of Cytochrome P450 (CYP1A2) and phosphodiesterase (PDE)
80288-49-9sc-215061
5 mg
$278.00
2
8-CPT-cAMP
An efficient activator of cGK and cAMP-PK, and inhibitor of PDE
93882-12-3sc-201569
sc-201569A
20 mg
100 mg
$67.00
$265.00
16
Prazosin hydrochloride
An andrenergic α1, α2B-adrenoceptor, & MT3 receptor antagonist
19237-84-4sc-204858
100 mg
$79.00
3
EHNA hydrochloride
An inhibitor of adenosine deaminase and cyclic nucleotide phosphodiesterase- 2
51350-19-7sc-201184
sc-201184A
10 mg
50 mg
$62.00
$245.00
3
Vardenafil
A selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5)
224785-90-4sc-362054
sc-362054A
100 mg
1 g
$440.00
$550.00
3
Papaverine hydrochloride
An alkaloid that may inhibit phosphodiesterases and/or calcium channel actions
61-25-6sc-202273
5 g
$30.00
4
5prime-Deoxy-5prime-methylthioadenosine
An endogenous methylthioadenosine phosphorylase substrate and potent inhibitor of PDE
2457-80-9sc-202427
50 mg
$89.00
0
Quercetin Dihydrate
A natural flavonoid antiproliferative kinase inhibitor
6151-25-3sc-203225
sc-203225A
5 g
25 g
$31.00
$39.00
1
Luteolin
An inhibitor of glutathione S-transferase and 15-LO
491-70-3sc-203119
sc-203119A
sc-203119B
sc-203119C
sc-203119D
5 mg
50 mg
500 mg
5 g
500 g
$20.00
$25.00
$60.00
$80.00
$1,850.00
7
Enniatin B
An ionophore antibiotic that inhibits ACAT and PDE
917-13-5sc-202150
1 mg
$141.00
2
Ophiobolin A
An inhibitor of calmodulin action in calcium regulation
4611-05-6sc-202266
sc-202266A
sc-202266B
100 µg
1 mg
5 mg
$42.00
$240.00
$600.00
3
Dipyridamole
A phosphodiester, cGMP, and non-specific nucleoside transport inhibitor
58-32-2sc-200717
sc-200717A
1 g
5 g
$29.00
$98.00
0
MDL-12,330A dot HCl
An A cyclase inhibitor
40297-09-4sc-201574
sc-201574A
5 mg
25 mg
$65.00
$269.00
7
Theobromine
A weak phosphodiesterase inhibitor and adenosine receptor blocker
83-67-0sc-203296
sc-203296A
25 g
100 g
$34.00
$71.00
0
Cilostamide (OPC 3689)
A specific phosphodiesterase 3 (PDE3) inhibitor
68550-75-4sc-201180
sc-201180A
5 mg
25 mg
$64.00
$274.00
9
Cilostazol
A PDE inhibitor, antimitogenic, antithrombotic, and cardiotonic agent
73963-72-1sc-201182
sc-201182A
10 mg
50 mg
$69.00
$285.00
2
E6 Berbamine
A selective and cell-permeable CaM antagonist
73885-53-7sc-221573
sc-221573A
10 mg
50 mg
$109.00
$450.00
1
Butein
Inhibits the tyrosine kinase activity of the EGF receptor and p60c-src
487-52-5sc-202510
sc-202510A
5 mg
50 mg
$169.00
$300.00
4
Theophylline
An inhibitor of cyclic phosphodiesterase
58-55-9sc-202835
sc-202835A
5 g
25 g
$20.00
$30.00
6
Diphylline
An inhibitor of phosphodiesterase
479-18-5sc-364352
100 mg
$105.00
1
7-(beta-Hydroxyethyl)-theophylline
A weak phosphodiesterase inhibitor & an intermediate for 7-substituted xanthine
519-37-9sc-202836
5 g
$30.00
1
Irsogladine maleate
A PDE4 inhibitor and muscarinic acetylcholine receptor binder
84504-69-8sc-201190
sc-201190A
50 mg
250 mg
$64.00
$153.00
0
Malvidin chloride
A cell-cycle arresting compound
643-84-5sc-205952
10 mg
$319.00
0
Pentoxifylline
A non-selective phosphodiesterase inhibitor. Inhibits endotoxin-induced synthesis of TNF-α
6493-05-6sc-203184
1 g
$20.00
1
Vardenafil Dihydrochloride Salt
A selective phsphodiesterase type 5 (PDE5) inhibitor
224789-15-5sc-220368
sc-220368A
sc-220368B
10 mg
25 mg
50 mg
$220.00
$550.00
$700.00
0
Anagrelide hydrochloride
A potent type III phosphodiesterase inhibitor
58579-51-4sc-203513
sc-203513A
10 mg
50 mg
$101.00
$575.00
1
Caffeine-d9
An inhibitory compound which acts a cardiac and respiratory stimulant
72238-85-8sc-217818
2.5 mg
$300.00
0
Hydroxythiohomo Sildenafil
A thio analog of Sildenafil and a potential PDE5 inhibitor
479073-82-0sc-207746
1 mg
$300.00
0
Levosimendan
A Ca2+ sensitizer that increases contractile force of the myocardium
141505-33-1sc-204792
sc-204792A
100 mg
250 mg
$100.00
$220.00
0
YM 976
An inhibitor of PDE4
191219-80-4sc-204411
sc-204411A
10 mg
50 mg
$207.00
$825.00
0
Acetildenafil
A structural analog of Sidenafil
831217-01-7sc-207250
2.5 mg
$300.00
0
Enoximone
A selective phosphodiesterase III (PDE3) inhibitor
77671-31-9sc-252775
sc-252775A
10 mg
50 mg
$181.00
$728.00
1
Phosphodiesterase V Inhibitor II
An inhibitor of phosphodiesterase
sc-222167
5 mg
$175.00
0
Dipyridamole-D20 (Major)
A selective phosphodiesterase V (PDE 5) inhibitor
58-32-2 unlabeledsc-218245
1 mg
$250.00
0
Quercetin
A PI 3-kinase inhibitor, GPR30 activator, and apoptosis inducer
117-39-5sc-206089
sc-206089A
sc-206089B
sc-206089E
sc-206089C
sc-206089D
100 mg
500 mg
25 g
100 g
250 g
1 kg
$10.00
$15.00
$39.00
$100.00
$240.00
$900.00
8
Aminophylline
A non-selective phosphodiesterase inhibitor
317-34-0sc-252368
25 g
$35.00
0
Theophylline monohydrate
An inhibitor of PDE
5967-84-0sc-280133
50 g
$41.00
0
ICI 63197
An inhibitor of phosphodiesterase 4 competitive with rolipram
27277-00-5sc-203600
sc-203600A
10 mg
50 mg
$140.00
$575.00
0
Zaprinast (MB 22948)
An inhibitor of cGMP-specific phosphodiesterase
37762-06-4sc-201206
sc-201206A
25 mg
100 mg
$70.00
$215.00
6
Vinpocetine
An inhibitor of Ca2+/CaM-PDE with neuroprotective properties
42971-09-5sc-201204
sc-201204A
20 mg
100 mg
$55.00
$214.00
2
Etazolate Hydrochloride
A potent inhibitor of cAMP phosphodiesterase (PDE4) and less potent cGMP phosphodiesterase inhibitor
35838-58-5sc-201186
sc-201186A
5 mg
25 mg
$59.00
$245.00
5
Denbufylline
A xanthine derivative PDE IV inhibitor
57076-71-8sc-203915
5 mg
$190.00
0
W-5
A CaM antagonist that inhibits Ca2+/calmodulin- regulated activities
61714-25-8sc-201500
sc-201500A
25 mg
500 mg
$66.00
$630.00
2
Doxofylline
A xanthine bronchodilator known to impede phosphodiesterase activities
69975-86-6sc-205658
sc-205658A
1 g
5 g
$80.00
$220.00
1
Quazinone (Ro 13-6438)
A phosphodiesterase inhibitor and novel cardiotonic agent with vasodilating properties
70018-51-8sc-201196
sc-201196A
10 mg
50 mg
$85.00
$328.00
0
8-Methoxymethyl-IBMX
A Cam-PDE selective inhibitor
78033-08-6sc-201192
sc-201192A
10 mg
50 mg
$169.00
$715.00
0
Milrinone
A phosphodietsterase 3 inhibitor
78415-72-2sc-201193
sc-201193A
10 mg
50 mg
$159.00
$670.00
5
MY-5445
A selective cGMP phosphodiesterase inhibitor
78351-75-4sc-201195
10 mg
$153.00
1
Trequinsin hydrochloride
An ultrapotent inhibitor of phosphodiesterase 3
78416-81-6sc-358713
10 mg
$235.00
0
S-(+)-Rolipram
An inhibitor of cyclic AMP-specific phosphodiesterase
85416-73-5sc-201200
5 mg
$147.00
0
R-(-)-Rolipram
A PDE IV inhibitor and anti-inflammatory agent
85416-75-7sc-201199
5 mg
$158.00
0
LY 171883
A selective leukotriene D4 antagonist
88107-10-2sc-203120
10 mg
$72.00
0
Zardaverine
A pyridazinone derivative and a selective inhibitor of phosphodiesterase type III and IV
101975-10-4sc-201208
sc-201208A
5 mg
25 mg
$86.00
$372.00
0
Siguazodan
A selective phosphodiesterase PDE III inhibitor and a potent inotropic agent
115344-47-3sc-201201
sc-201201A
5 mg
25 mg
$100.00
$398.00
0
CP 80633
A selective inhibitor of phosphodiesterase type 4
135637-46-6sc-205276
sc-205276A
10 mg
50 mg
$175.00
$739.00
0
Ibudilast
A nonselective phosphodiesterase inhibitor
50847-11-5sc-203080
10 mg
$210.00
1
Mesopram
An active phosphodiesterase (PDE) 4 inhibitor
189940-24-7sc-204077
sc-204077A
10 mg
50 mg
$175.00
$739.00
0
Reticulol
An isocoumarin metabolite shown to inactivate topoisomerase I
26246-41-3sc-202313
sc-202313A
250 µg
1 mg
$100.00
$213.00
0
1,3-Dipropylxanthine
An inhibitor of phosphodiesterase
31542-62-8sc-213513
50 mg
$240.00
0
Cilomilast-d9
A deuterium-labeled phosphodiesterase inhibitor
153259-65-5 (unlabeled)sc-217896
1 mg
$300.00
0
Roflumilast-d3
A deuterium-labeled PDE4 inhibitor
1189992-00-4sc-219987
1 mg
$300.00
0
Phosphodiesterase 4 Inhibitor
A pyrazole compound with an active site binding inhibitor of phosphodiester
346440-86-6sc-204190
sc-204190A
10 mg
50 mg
$280.00
$1,300.00
0
Anagrelide-13C3
A labeled type III phosphodiesterase inhibitor
sc-217646
1 mg
$450.00
0
Tadalafil-methyl-d3
A deuterium-labeled phosphodiesterase inhitibor
sc-220184
1 mg
$300.00
0
W-12, hydrochloride
A calmodulin antagonist that inhibits myosin light chain kinase
89108-46-3sc-203309
1 mg
$110.00
0
Obscurolide A1
A weak phosphodiesterase inhibitor isolated from Streptomyces viridochromogenes
144397-99-9sc-203167
sc-203167A
1 mg
5 mg
$90.00
$360.00
0
Icariin
An inhibitor of recombinant PDE5
489-32-7sc-279198
sc-279198A
sc-279198B
1 g
5 g
10 g
$134.00
$400.00
$793.00
0
BAY-60-7550
A PDE2 inhibitor
439083-90-6sc-396772
sc-396772A
1 mg
5 mg
$150.00
$450.00
4
Amrinone
A selective cAMP phosphodiesterase inhibitor
60719-84-8sc-207288
1 g
$153.00
0
GSK256066
A highly potent and selective inhibitor of phosphodiesterase 4
801312-28-7sc-364353
sc-364353A
10 mg
50 mg
$555.00
$1,600.00
0
1-Methyl-4-nitro-5-propyl-1H-pyrazole-3-carboxamide
An intermediate in the preparation of cGMP PDE5 inhibitors
247583-72-8sc-397129
10 mg
$250.00
0
1,3-Dipropyl-7-methylxanthine
A PDE inhibitor
31542-63-9sc-206245
25 mg
$210.00
0
4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide
A hypolipidemic and possible PDE1 inhibitor
139756-02-8sc-357666
1 g
$74.00
0
Dipyridamole Di-O-beta-D-glucuronide
A metabolite of dipyridamole, a PDE 5 inhibitor
107136-95-8sc-221552
1 mg
$420.00
0
Tadalafil
A phosphodiesterase 5 inhibitor
171596-29-5sc-208412
50 mg
$126.00
6
N-Desethyl Acetildenafil
147676-55-9sc-208022
2.5 mg
$350.00
0
Avanafil
A derivative of pyrimidine that acts as phosphodiesterase-5 inhibitor
330784-47-9sc-397683
10 mg
$220.00
0
Hydroxy vardenafil
224785-98-2sc-488984
2.5 mg
$300.00
0
Pentoxifylline-d6
A labeled metabolite of pentifylline
1185878-98-1sc-219571
1 mg
$350.00
0
Sildenafil-d3
A deuterium-labelled analog of Sildenafil
1126745-90-1sc-220101
1 mg
$220.00
0
Propoxyphenyl Thioaildenafil
856190-49-3sc-477058
5 mg
$300.00
0
Papaverine
A phosphodiesterase inhibitor
58-74-2sc-279951
sc-279951A
sc-279951B
10 mg
50 mg
100 mg
$150.00
$260.00
$450.00
0
RS 25344 hydrochloride
A potent and selective phosphodiesterase (PDE) 4 inhibitor
152815-28-6sc-296280
sc-296280A
10 mg
50 mg
$169.00
$715.00
0
4-{[3prime,4prime-(Methylenedioxy)benzyl]amino}-6-methoxyquinazoline
An inhibitor of cGMP-specific phosphodiesterase
150450-42-3sc-352371
1 mg
$140.00
0
Paraxanthine
An adenosine receptor ligand and a major metabolite of caffeine
611-59-6sc-212526
100 mg
$160.00
0
Tropinone
A Phosphodiesterase IV (PDE 4) inhibitor.
532-24-1sc-253807
sc-253807A
5 g
10 g
$35.00
$65.00
0
Rolipram
A selective, cell permeable inhibitor of cAMP-specific phosphodiesterase (PDE4)
61413-54-5sc-3563
sc-3563A
5 mg
50 mg
$64.00
$197.00
11
Gisadenafil besylate
A PDE5 inhibitor
334827-98-4sc-361185
sc-361185A
5 mg
25 mg
$97.00
$368.00
0
CDP 840 hydrochloride
A selective and potent inhibitor of PDE 4
162542-90-7sc-362723
sc-362723A
10 mg
50 mg
$175.00
$739.00
0
BC 11-38
A selective inhibitor of phosphodiesterase 11
686770-80-9sc-364350
sc-364350A
10 mg
50 mg
$160.00
$642.00
0
PF-2545920
An inhibitor of phosphodiesterase 10A
1292799-56-4sc-364355
sc-364355A
5 mg
10 mg
$405.00
$555.00
0
Quercetin-d3 (Major)
CAS: 263711-79-1, MF: C15H7D3O7, MW: 305.25
263711-79-1sc-476756
2.5 mg
$300.00
0
Anagrelide
A Phosphodiesterase 3 Inhibitor
68475-42-3sc-491875
25 mg
$147.00
0

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