Met Inhibitors

Santa Cruz Biotechnology now offers a broad range of Met Inhibitors. MET (c-Met) is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). MET is a membrane receptor that is essential for embryonic development and wound healing. Cancer stem cells are thought to adopt the ability to express MET, and thus become the cause of cancer persistence. Met Inhibitors offered by Santa Cruz inhibit Met and, in some cases, other hepatocyte growth factor and tumor growth related proteins. View detailed Met Inhibitor specifications, including Met Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
PHA 665752
A Met inhibitor which prevents tumorigenicity in lung cancer xenografts
477575-56-7 sc-203186
sc-203186A
sc-203186B
sc-203186C
2 mg
10 mg
50 mg
200 mg
$140.00
$275.00
$700.00
$1,480.00
14
BMS 777607
A small-molecule inhibitor of Met, Axl, Ron and Tyro3
1025720-94-8 sc-364438
sc-364438A
10 mg
50 mg
$379.00
$1,215.00
0
VEGFR2 Kinase Inhibitor III
A VEGFR2, Met, RET, PDGFR, and ALK inhibitor
204005-46-9 sc-202851
5 mg
$77.00
4
Met Kinase Inhibitor
A competitive inhibitor of Met kinase activity
658084-23-2 sc-204801
1 mg
$116.00
3
Foretinib
An ATP-competitive inhibitor of tyrosine kinases including Flt-1, Flt-4, Met, and Ron
849217-64-7 sc-364492
5 mg
$126.00
0
K-252a
A cell permeable protein kinase inhibitor
99533-80-9 sc-200517
sc-200517A
sc-200517B
100 µg
1 mg
500 µg
$118.00
$473.00
$200.00
4
RPI-1
A cell-permeable ATP-competitive tyrosine kinase inhibitor
269730-03-2 sc-255524
sc-255524A
5 mg
10 mg
$150.00
$182.00
3
XL-184 free base
A potent VEGFR2 and Met inhibitor
849217-68-1 sc-364657
sc-364657A
5 mg
10 mg
$90.00
$200.00
1
Sodium succinate dibasic
An inhibitor of receptor tyrosine kinases
150-90-3 sc-251053
100 g
$26.00
0
AMG-208
A highly selective Met inhibitor (IC50 = 9.3 nM)
1002304-34-8 sc-364399
sc-364399A
10 mg
50 mg
$645.00
$1,950.00
0
MK-2461
A multi-targeted inhibitor
917879-39-1 sc-364538
sc-364538A
5 mg
10 mg
$540.00
$825.00
0
JNJ-38877605
An ATP-competitive inhibitor for the catalytic activity of Met
943540-75-8 sc-364516
sc-364516A
2 mg
10 mg
$126.00
$365.00
0
INCB28060
A novel inhibitor of Met (IC50 = 0.13 nM)
1029712-80-8 sc-364510
sc-364510A
10 mg
50 mg
$305.00
$750.00
0
EMD 1214063
A potent and selective Met inhibitor
1100598-32-0 sc-364487
sc-364487A
10 mg
50 mg
$285.00
$772.00
1
c-Met/RON Dual Kinase Inhibitor Inhibitor
An inhibitor of both Met and Ron
913376-84-8 sc-364532
sc-364532A
sc-364532B
sc-364532C
sc-364532D
5 mg
50 mg
100 mg
500 mg
1 g
$379.00
$1,200.00
$1,700.00
$3,600.00
$7,000.00
0
4,4prime-Bis(4-aminophenoxy)biphenyl
A potent Flk-1 (VEGFR2) and Tie-2 inhibitor
13080-85-8 sc-267771
5 g
$100.00
0
MGCD-265
An inhibitor of Met, Flt-1, Flt-4, Flk-1, Ron, and Tie2
875337-44-3 sc-364533
sc-364533A
10 mg
50 mg
$480.00
$1,463.00
0
Met Kinase Inhibitor III
An ATP-competitive inhibitor of Met
sc-364531
2 mg
$224.00
0
ARQ 197
A novel and selective human Met inhibitor (IC<sub>50</sub> = 0.1 µM)
905854-02-6 sc-364408
sc-364408A
50 mg
200 mg
$712.00
$1,920.00
0
AMG458
A potent inhibitor of human and mouse Met
913376-83-7 sc-364400
sc-364400A
10 mg
50 mg
$555.00
$1,606.00
0
SGX-523
A Met inhibitor
1022150-57-7 sc-364616
sc-364616A
5 mg
25 mg
$255.00
$681.00
0
BMS 794833
A potent ATP competitive inhibitor of Met and Flk-1
1174046-72-0 sc-364439
sc-364439A
10 mg
50 mg
$320.00
$970.00
0
NVP-BVU972
A selective and potent Met inhibitor (IC50 = 14 nM)
1185763-69-2 sc-364555
sc-364555A
10 mg
50 mg
$555.00
$1,606.00
0

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