The accumulation of unfolded proteins within the endoplasmic recticulum (ER) of yeast and mammalian cells activates the unfolded protein response (UPR) pathway and leads to the transcription of ER-specific genes involved in protein folding. Biochemicals that inhibit IRE1 have many applications in biochemical and physiological research. Click on the product name to view detailed information such as the chemical structure and specific chemical properties for each of our IRE1 Inhibitors. In stock IRE1 Inhibitors are available for immediate shipping.
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