GSK Inhibitors

Glycogen synthase kinase 3, or GSK-3, is a serine/threonine, proline-directed kinase involved in a diverse array of signaling pathways, including glycogen synthesis and cellular adhesion, and has been implicated in Alzheimer's disease. Biochemicals that inhibit GSK have many applications in biochemical and physiological research. Click on the product name to view detailed information such as the chemical structure and specific chemical properties for each of our GSK Inhibitors. In stock GSK Inhibitors are available for immediate shipping.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Ro 31-8220
A cell-permeable PKC inhibitor that has been shown to be selective for PKC over CaM kinase II and PKA
138489-18-6 sc-200619
1 mg
$81.00
8
Kenpaullone
A Cdk and GKS-3 inhibitor
142273-20-9 sc-200643
sc-200643A
1 mg
5 mg
$59.00
$263.00
1
SB-216763
A potent, selective and ATP-competitive inhibitor of GSK-3α and GSK-3β
280744-09-4 sc-200646
sc-200646A
1 mg
5 mg
$64.00
$189.00
14
Cdk1/5 Inhibitor
A 3-amino substituted pyrazoloquinoxaline compound and selective inhibitor of Cdk1/Cdk5
40254-90-8 sc-202094
sc-202094A
sc-202094B
1 mg
5 mg
10 mg
$60.00
$200.00
$360.00
2
Valproic acid sodium salt
An HDAC inhibitor with anticancer, anti-inflammatory and neuroprotective effects
1069-66-5 sc-202378
5 g
$31.00
6
Bisindolylmaleimide I (GF 109203X)
A highly selective inhibitor of all PKC isoforms and slight inhibitor of GSK-3
133052-90-1 sc-24003
sc-24003A
5 mg
1 mg
$174.00
$150.00
21
Bisindolylmaleimide I, HCl
A water soluble inhibitor for all known isoforms of PKC
176504-36-2 sc-24004
1 mg
$139.00
9
4-Bromoindole
A potential inhibitor of GSK-3
52488-36-5 sc-216790
100 mg
$165.00
0
Indole-3-acetamide
A GSK-3β, VEGF, and JAK3 inhibitor
879-37-8 sc-255213
sc-255213A
1 g
5 g
$44.00
$198.00
0
GSK-3 Inhibitor XIII
An ATP-binding site inhibitor of GSK-3
404828-08-6 sc-203987
sc-203987A
1 mg
5 mg
$158.00
$462.00
0
BIP-135
A GSK-3 inibitor with modest efficacy against PKC and PI3K
941575-71-9 sc-364435
sc-364435A
5 mg
25 mg
$87.00
$369.00
0
Ellagic Acid, Dihydrate
A CK2, Topo I and II, FGR, GSK, and PKA inhibitor
314041-08-2 sc-202598
sc-202598A
500 mg
5 g
$50.00
$85.00
0
GSK-3 Inhibitor IX
A cell-permeable, potent, selective, reversible GSK-3α/β inhibitor
667463-62-9 sc-202634
sc-202634A
1 mg
10 mg
$56.00
$180.00
1
GSK-3beta Inhibitor VII
A cell-permeable, and non-ATP competitive inhibitor of GSK-3β
99-73-0 sc-202635
5 mg
$129.00
0
GSK-3beta Inhibitor VIII
A potent, selective inhibitor of GSK-3β
487021-52-3 sc-202636
sc-202636A
5 mg
10 mg
$128.00
$144.00
3
Aloisine, RP106
A selective, potent, ATP-competitive inhibitor of CDK1/cyclin B, CDK5/p25, and GSK-3
496864-15-4 sc-202452
sc-202452A
1 mg
5 mg
$31.00
$139.00
0
Indirubin-3prime-monoxime
A potent inhibitor of GSK-3β, Cdk1, and Cdk5
160807-49-8 sc-202660
sc-202660A
sc-202660B
1 mg
5 mg
50 mg
$75.00
$309.00
$645.00
0
(Methoxycarbonylmethyl)triphenylphosphonium bromide
A reactant for the synthesis of GSK-3 inhibitors using the Wittig reaction
1779-58-4 sc-228467
50 g
$67.00
0
Isogranulatimide
Cell-permeable alkaloid that acts as a potent and ATP-competitive inhibitor of Chk1
244148-46-7 sc-202667
1 mg
$700.00
0
GSK-3beta Inhibitor XI
A potent and specific ATP-competitive inhibitor of GSK-3Β
626604-39-5 sc-204770
1 mg
$224.00
1
SB-415286
An ATP-competitive inhibitor of GSK3α and GSK-3β
264218-23-7 sc-204901
sc-204901A
1 mg
5 mg
$62.00
$140.00
3
GSK-3 Inhibitor IX, Control, MeBIO
A cell-permeable N-methylated kinase inactive analog of GSK-3 Inhibitor IX
710323-61-8 sc-221688
1 mg
$135.00
0
GSK-3 Inhibitor X
A selective GSK-3α/β inhibitor
740841-15-0 sc-221689
5 mg
$130.00
3
5-Bromoindole
A potential inhibitor of GSK-3
10075-50-0 sc-256902
5 g
$28.00
0
GSK-3 Inhibitor XV
A highly bioreactive inhibitor to GSK-3α, GSK-3β. and PIM-1 kinase
sc-221690
1 mg
$539.00
0
GSK-3 Inhibitor XVI
A compound that acts as potent, ATP-competitive & highly selective GSK-3 inhibitor
252917-06-9 sc-221691
sc-221691A
5 mg
25 mg
$285.00
$890.00
2
GSK-3beta Inhibitor I
A thiadiazolidinone analog that acts as a highly selective, non-ATP competitive inhibitor of GSK-3β
327036-89-5 sc-221692
5 mg
$179.00
0
GSK-3beta Inhibitor VI
A cell-permeable, irreversible, and non-ATP competitive inhibitor of GSK-3β
62673-69-2 sc-221693
5 mg
$145.00
0
GSK-3beta Inhibitor XII, TWS119
A cell-permeable agent shown to act as a potent inhibitor of GSK-3β
601514-19-6 sc-221694
sc-221694A
1 mg
5 mg
$55.00
$150.00
3
Indirubin-3prime-monoxime-5-sulphonic Acid
An inhibitor of GSK-3β, Cdk1 and Cdk5.
331467-05-1 sc-221753
1 mg
$179.00
0
5-Iodo-Indirubin-3prime-monoxime
An inhibitor of GSK-3β, CDK-1, and CDK-5
sc-221754
1 mg
$104.00
0
GSK-3 Inhibitor II
A potent GSK-3β inhibitor
478482-75-6 sc-24020
sc-24020A
5 mg
25 mg
$80.00
$290.00
9
1-Azakenpaullone
A Kenpaullone analog and an inhibitor of GSK-3
676596-65-9 sc-358615
1 mg
$96.00
0
TCS 2002
A cell-permeable inhibitor of GSK-3β
1005201-24-0 sc-359020
sc-359020A
10 mg
50 mg
$175.00
$739.00
0
3F8
A selective and potent GSK-3β inhibitor
159109-11-2 sc-361080
sc-361080A
10 mg
50 mg
$159.00
$670.00
0
TCS 21311
A potent inhibitor of JAK3
1260181-14-3 sc-362804
sc-362804A
10 mg
50 mg
$229.00
$970.00
0
A 1070722
An inhibitor of GSK-3α and GSK-3β with a Ki = 0.6 nM respectively
1384424-80-9 sc-364392
sc-364392A
10 mg
50 mg
$131.00
$709.00
0

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