EGFR Inhibitors

Santa Cruz Biotechnology now offers a broad range of EGFR Inhibitors. The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Upregulation of EGFR is associated with tumor progression. Abrogation of EGFR may be achieved with the use of EGFR Inhibitors with potential results in cell cycle arrest, apoptosis or dedifferentiation of cancer cells. EGFR Inhibitors offered by Santa Cruz inhibit EGFR and, in some cases, other receptor tyrosine kinases and tumor progression related proteins. View detailed EGFR Inhibitor specifications, including EGFR Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Erlotinib Hydrochloride
A HER-1/EGFR tyrosine kinase inhibitor
183319-69-9 sc-202154
sc-202154A
10 mg
25 mg
$68.00
$112.00
22
Gefitinib
An EGFR-tyrosine kinase inhibitor
184475-35-2 sc-202166
sc-202166A
100 mg
250 mg
$50.00
$100.00
23
AG-490
A tyrosine kinase inhibitor of JAK2, EGFR, JAK3 and Neu
133550-30-8 sc-202046
sc-202046A
10 mg
50 mg
$78.00
$312.00
12
Lapatinib ditosylate
A selective and effective inhibitor of ErbB-2 and EGFR dual tyrosine kinases
388082-78-8 sc-202205
sc-202205A
sc-202205B
10 mg
25 mg
5 mg
$63.00
$105.00
$38.00
12
Tyrphostin AG 1478
A potent and selective inhibitor of EGFR
175178-82-2 sc-200613
sc-200613A
5 mg
25 mg
$87.00
$400.00
9
CL-387,785
An irreversible inhibitor of EGF-receptor kinase activity
194423-06-8 sc-221429
1 mg
$134.00
0
Hypericin
A kinase inhibitor with antiviral activity
548-04-9 sc-3530
sc-3530A
1 mg
5 mg
$58.00
$200.00
5
Erbstatin Analog
A stable inhibitor of EGFR tyrosine kinase
63177-57-1 sc-200511
sc-200511A
5 mg
25 mg
$81.00
$299.00
4
CGP-74514A hydrochloride
A Cdk inhibitor
1173021-98-1 sc-300344
sc-300344A
5 mg
25 mg
$220.00
$796.00
0
Herbimycin A
An inhibitor of c-Abl, HSP 90, c-Src, c-Yes, Fes, and Ros
70563-58-5 sc-3516
sc-3516A
100 µg
1 mg
$151.00
$940.00
11
PD 168393
A potent, cell-permeable, irreversible inhibitor of EGFR
194423-15-9 sc-222138
1 mg
$162.00
2
Daphnetin
A coumarin analog that acts as an inhibitor of several protein kinases
486-35-1 sc-203022
10 mg
$80.00
0
Afatinib
An irreversible and potent EGFR/Neu inhibitor, inhibits EGFR phosphorylation
439081-18-2 sc-364398
sc-364398A
5 mg
10 mg
$100.00
$180.00
0
Lapatinib
An antineoplastic agent used in breast cancer research
231277-92-2 sc-353658
100 mg
$399.00
17
PKC-412
A broad spectrum tyrosine kinase inhibitor
120685-11-2 sc-200691
sc-200691A
1 mg
5 mg
$114.00
$450.00
8
PD 174265
A potent, cell-permeable, reversible, and selective inhibitor of EGFR tyrosine kinase activity
216163-53-0 sc-204170
1 mg
$137.00
2
Tyrphostin 51
A potent inhibitor of EGFRK activity showing mixed competitive inhibition with ATP and substrate1-3.
122520-90-5 sc-200545
sc-200545A
5 mg
25 mg
$58.00
$299.00
0
Butein
Inhibits the tyrosine kinase activity of the EGF receptor and p60c-src
487-52-5 sc-202510
sc-202510A
5 mg
50 mg
$169.00
$300.00
4
Vatalanib Dihydrochloride
A potent inhibitor of EGFR- and RET-dependent tumor cell proliferation and survival
212141-51-0 sc-202379
sc-202379A
5 mg
25 mg
$125.00
$374.00
0
PP 3
A negative control for the Src family protein tyrosine kinase inhibitor PP2
5334-30-5 sc-203213
1 mg
$80.00
1
Tyrphostin 47
A potent inhibitor of EGFR kinase activity
122520-86-9 sc-200543
sc-200543A
5 mg
25 mg
$77.00
$309.00
4
AG 494
A potent and selective inhibitor of EGFR tyrosine kinase
133550-35-3 sc-202043
sc-202043A
10 mg
50 mg
$69.00
$255.00
0
Tyrphostin AG 112
An EGFR inhibitor
144978-82-5 sc-222381
5 mg
$23.00
0
WHI-P 154
A JAK3 inhibitor which inhibits other common kinases
211555-04-3 sc-204395
sc-204395A
10 mg
50 mg
$109.00
$615.00
0
RPI-1
A cell-permeable ATP-competitive tyrosine kinase inhibitor
269730-03-2 sc-255524
sc-255524A
5 mg
10 mg
$150.00
$182.00
3
AZD8931
A potent inhibitor of EGFR phosphorylation
848942-61-0 sc-364426
sc-364426A
5 mg
10 mg
$255.00
$480.00
0
CUDC-101
A potent inhibitor to HDAC, EGFR and HER2
1012054-59-9 sc-364474
sc-364474A
10 mg
50 mg
$190.00
$700.00
0
Tyrphostin A1
An inactive Tyrphostin used as a negative control for Tyrphostin A23
2826-26-8 sc-3559
sc-3559A
25 mg
100 mg
$147.00
$179.00
1
Compound 56
A potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor
171745-13-4 sc-203430
500 µg
$164.00
2
XL647
A potent and selective EGFR phosphorylation inhibitor
651031-01-5 sc-364659
sc-364659A
5 mg
10 mg
$305.00
$560.00
0
AG 43
A useful negative control in EGFR tyrosine kinase assays
5553-97-9 sc-202916
5 mg
$52.00
0
(+)shy-Aeroplysinin-1
A compound that is an inhibitor of EGFR kinase
28656-91-9 sc-202445
100 µg
$36.00
0
Lavendustin C
An inhibitor of CaMKII
125697-93-0 sc-202207
sc-202207A
2 mg
10 mg
$41.00
$155.00
0
PD 153035
An extremely potent and specific inhibitor of EGFR tyrosine kinase activity
153436-54-5 sc-205909
5 mg
$68.00
3
OSI-420, Free Base (Desmethyl Erlotinib)
A metabolite of Erlotinib
183321-86-0 sc-212485
1 mg
$254.00
1
WZ 4002
An EGFR phosphorylation inhibitor
1213269-23-8 sc-364655
sc-364655A
10 mg
50 mg
$180.00
$744.00
0
Tyrphostin B44, (-) enantiomer
A potent inhibitor of (EGFR) kinase
133550-32-0 sc-203711
5 mg
$23.00
0
Tyrphostin B44, (+) enantiomer
An EGFR kinase inhibitor
133550-37-5 sc-203305
5 mg
$30.00
0
Angiogenesis Inhibitor
A cell-permeable indolinone
186611-44-9 sc-221253
10 mg
$198.00
0
PD 161570
A selective FGFR inhibitor
192705-80-9 sc-361284
sc-361284A
5 mg
25 mg
$112.00
$446.00
0
Neratinib
A potent and selective inhibitor of EGFR and HER2
698387-09-6 sc-364549
sc-364549A
5 mg
25 mg
$120.00
$500.00
0
HDS 029
A potent inhibitor of EGF receptor family
881001-19-0 sc-203995
sc-203995A
1 mg
10 mg
$105.00
$215.00
0
Erlotinib-d6, Hydrochloride Salt
A labeled form of Erlontinib HCl, a potent EGFR autophosphorylation inhibitior
sc-218329
1 mg
$180.00
6
Lavendustin C methyl ester
An inhibitor of EGFR tyrosine kinase activity
sc-221838
sc-221838A
1 mg
5 mg
$26.00
$137.00
0
Lapatinib-13C2,15N Ditosylate
An inhibitor of ErbB1 and ErbB2 tyrosine kinases
sc-280905
500 µg
$250.00
0
JAK3 Inhibitor V
A selective JAK3 inhibitor
4452-06-6 sc-295218
10 mg
$125.00
0
RO 106-9920
A NF-kB-dependent cytokine expression, 5-LO, and EGFR inhibitor
62645-28-7 sc-203240
sc-203240A
1 mg
5 mg
$135.00
$575.00
5
Tyrphostin A25
A cell-permeable, reversible, and competitive protein tyrosine kinase (PTK) substrate inhibitor
118409-58-8 sc-3555
sc-3555A
25 mg
5 mg
$276.00
$67.00
8
Tyrphostin AG 99
A potent, cell-permeable and reversible inhibitor of EGFR and EGF-dependent cell proliferation
118409-59-9 sc-202847
sc-202847A
5 mg
25 mg
$54.00
$184.00
0
Lavendustin A
A selective and potent inhibitor of the receptor tyrosine kinase
125697-92-9 sc-200539
sc-200539A
1 mg
5 mg
$116.00
$456.00
0
Tyrphostin B42
A potent JAK2 inhibitor
133550-30-8 sc-3556
5 mg
$26.00
3
AG 555
A potent epidermal growth factor receptor kinase inhibitor
133550-34-2 sc-203500
sc-203500A
10 mg
50 mg
$69.00
$330.00
2
AG 556
Inhibitor of EGFR kinase autophosphorylation over HER1/2 autophosphorylation
133550-41-1 sc-202044
sc-202044A
5 mg
25 mg
$30.00
$62.00
0
RG-13022
An inhibitor of the EGF and PDGF receptor tyrosine kinases
136831-48-6 sc-200591
sc-200591A
5 mg
10 mg
$95.00
$175.00
1
Lavendustin B
A tyrosine kinase inhibitor
125697-91-8 sc-200595
sc-200595A
1 mg
5 mg
$64.00
$249.00
1
Tyrphostin RG 14620
A non-phenolic tyrphostin analog selective for the EGF receptor
136831-49-7 sc-200593
sc-200593A
5 mg
10 mg
$64.00
$130.00
0
DAPH
An inhibitor of EGFR kinase 3
145915-58-8 sc-200698
5 mg
$130.00
0
AG 825
A selective ErbB2 (Neu) inhibitor and apoptosis inducer
149092-50-2 sc-202045
sc-202045A
2 mg
5 mg
$45.00
$90.00
0
PD 158780 solution
A potent tyrosine kinase inhibitor
171179-06-9 sc-202758
500 µg
$159.00
0
BPIQ-II HCl Salt
A specific and potent EGFR tyrosine kinase activity inhibitor
171179-32-1 (free base) sc-221375
1 mg
$203.00
0
EGFR/ErbB-2 Inhibitor
A potent reversible inhibitor of EGFR and c-erbB2
179248-61-4 sc-203935
1 mg
$99.00
0
Didesmethyl Erlotinib Hydrochloride Salt
A metabolite of Erlotinib
183320-12-9 sc-207566
1 mg
$350.00
0
Desmethyl Erlotinib Acetate
A derivative of Ertolinib, a potent EGFR inhibitor
183320-15-2 sc-218150
1 mg
$350.00
0
PD 153035 Hydrochloride
A potent inhibitor of epidermal growth factor (EGF) receptor tyrosine kinase
183322-45-4 sc-205963
sc-205963A
10 mg
50 mg
$125.00
$525.00
0
3-(4-Isopropylbenzylidenyl)shyindolin-2-one
A non-selective inhibitor of RTKs
186611-55-2 sc-202413
sc-202413A
1 mg
5 mg
$39.00
$206.00
0
BIBX 1382
A potent, reversible, selective inhibitor of EGFR
196612-93-8 sc-202497
5 mg
$180.00
0
GW2974
A selective dual EGFR and ErbB-2 inhibitor
202272-68-2 sc-252869
25 mg
$240.00
0
PD 166285
An inhibitor of RTK, c-Src, FGFR1, Wee 1, and PDGFRβ
212391-63-4 sc-208153
5 mg
$100.00
1
Pelitinib
An EGFR inhibitor
257933-82-7 sc-208155
5 mg
$350.00
0
Canertinib
An irreversible pan-erbB tyrosine kinase inhibitor
267243-28-7 sc-207397
10 mg
$220.00
0
ZM 323881 hydrochloride
A receptor tyrosine kinase inhibitor of VEGFR-2 (Flk-1), PDGFR-beta, EGFR, and FGFR1
324077-30-7 sc-296861
sc-296861A
1 mg
10 mg
$105.00
$164.00
0
Vandetanib
An antagonist of VEGFR (Flk and Flk) and EGFR families.
443913-73-3 sc-220364
sc-220364A
5 mg
50 mg
$167.00
$1,353.00
0
EGFR Inhibitor III
Inhibits EGFR- kinase activity, blocking phosphorylation
733009-42-2 sc-221580
5 mg
$379.00
0
EGFR Inhibitor
A highly selective, cell-permeable EGFR inhibitor
879127-07-8 sc-203934
1 mg
$99.00
0
JNJ 28871063 hydrochloride
A potent inhibitor of ErbB receptors
944341-54-2 sc-204025
sc-204025A
10 mg
50 mg
$185.00
$772.00
1
EGF/FGF/PDGF receptor tyrosine kinase Inhibitor
A tyrosine kinase inhibitor that inhibits human FGFR-1, PDGFR-β, c-Scr, & EGFR
1135256-66-4 sc-221579
2 mg
$290.00
1
AST 1306
A potent and selective inhibitor of EGFR phosphorylation
1050500-29-2 sc-364413
sc-364413A
5 mg
10 mg
$420.00
$600.00
0
2prime-Thioadenosine
A potent, selective inhibitor of ErbB1/ErbB2
60239-18-1 (non-salt) sc-220826
2 mg
$270.00
0
Gefitinib hydrochloride salt
A potent inhibitor of EGFR tyrosine kinase activity
184475-55-6 sc-337854
1 g
$300.00
1
ARRY334543
A potent and selective EGFR phosphorylation inhibitor
845272-21-1 sc-364410
sc-364410A
5 mg
10 mg
$487.00
$667.00
0
Src/EGFR Inhibitor
A synthetic inhibitor for Src and EGFR
131023-24-0 sc-3050
0.5 mg
$89.00
0
Gefitinib O-Methyl-D3
A derivative of Gefitinib, an EGFR inhibitor
sc-218566
1 mg
$300.00
0
OSI-420-d4, Free Base (Desmethyl Erlotinib-d4)
A labeled metabolite of Erlotinib, an EGFR inhibitor
sc-219500
1 mg
$600.00
0
LFM-A12
A potent and specific inhibitor of EGFR tyrosine kinase activity
sc-295360
sc-295360A
500 µg
1 mg
$296.00
$400.00
0
BPDQ
A potent, reversible, and specific inhibitor of EGFR tyrosine kinase
169205-87-2 sc-311299
1 mg
$160.00
0
Tyrphostin 47
An inhibitor of EGFR tyrosine kinase
118409-60-2 sc-216031
5 mg
$64.00
0
Tyrphostin AG 528
An inhibitor of EGFR tyrosine kinase activity
133550-49-9 sc-216034
5 mg
$42.00
0
BPIQ-I
A potent and specific inhibitor of tyrosine kinase activity of EGFR
174709-30-9 sc-202507
1 mg
$150.00
0
Gefitinib 2hydrochloride salt
A potent and selective inhibitor of EGFR kinase
184475-56-7 sc-337853
1 g
$1,950.00
0
Canertinib Dihydrochloride
A water-soluble, EGFR, HER2, and ErbB-4 tyrosine kinase inhibitor
289499-45-2 sc-396066
25 mg
$113.00
0
GW 583340 dihydrochloride
A potent inhibitor of EGFR/ErbB2
388082-81-3 sc-224012
sc-224012A
1 mg
5 mg
$215.00
$850.00
0
BIBU 1361 dihydrochloride
A selective EGFR kinase inhibitor
793726-84-8 sc-203844
sc-203844A
1 mg
10 mg
$95.00
$209.00
0
TAK 285
A potent and selective EGFR and HER2 inhibitor
871026-44-7 sc-364627
sc-364627A
5 mg
10 mg
$405.00
$700.00
0
3-(4-Hydroxybenzylidenyl)shyindolin-2-one
A selective receptor tyrosine kinase (RTK) inhibitor shown to inhibit FLK-1 RTK
293302-14-4 sc-202412
sc-202412A
1 mg
5 mg
$55.00
$216.00
0
WZ 3146
A mutant EGFR phosphorylation inhibitor
1214265-56-1 sc-364654
sc-364654A
5 mg
10 mg
$305.00
$480.00
0
WZ8040
A potent inhibitor of EGFR T790M
1214265-57-2 sc-364656
sc-364656A
5 mg
10 mg
$255.00
$480.00
0
O-Desmethyl Gefitinib
A major metabolite of Gefitinib
847949-49-9 sc-212448
1 mg
$220.00
0
O-Desmorpholinopropyl Gefitinib
A metabolite of gefitinib, an EGFR inhibitor
184475-71-6 sc-212456
1 g
$300.00
0
TAK 165
A selective, potent, and irreversible ErbB2 and EGFR inhibitor
366017-09-6 sc-361372
sc-361372A
10 mg
50 mg
$139.00
$781.00
0
CGP 74514A
An inhibitor of CDK1/cyclin B, PKCα, PKA, and EGFR
sc-391004
sc-391004B
5 mg
25 mg
$80.00
$279.00
0
Erlotinib, Free Base
A tyrosine kinase inhibitor
183321-74-6 sc-396113
sc-396113A
sc-396113B
sc-396113C
500 mg
1 g
5 g
10 g
$74.00
$120.00
$272.00
$475.00
22
O-tert-Butyl-dimethylsilyl Curcumin
A protected Curcumin
911292-36-9 sc-396137
100 mg
$210.00
0
Tyrphostin AG 30
A potent PTK inhibitor
122520-79-0 sc-202042
sc-202042A
5 mg
10 mg
$33.00
$80.00
0
PD 158780
A potent tyrosine kinase inhibitor that can permeate cells
171179-06-9 sc-358789
10 mg
$127.00
0
AST-1306
897383-62-9 sc-503138
5 mg
$450.00
0

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