Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Crosslinkers. Crosslinkers are used in the discovery of the molecular mechanisms of protein-protein interactions. Crosslinkers are either homo- or hetero-bifunctional reagents with identical or non-identical reactive groups, respectively, permitting the establishment of inter- as well as intra-molecular crosslinkages. View detailed Crosslinker specifications, including CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
sc-496718
500 mg
$420.00
0
Biotin-PEG11-Mal
1334172-60-9 sc-496064
50 mg
$575.00
0
Mal-amido-PEG8-acid
1334177-86-4 sc-496707
100 mg
$360.00
0
5-(3-Iodopropoxy)-2-nitrobenzyl alcohol
A photolabile linker for solid-phase oligosaccharide synthesi
185994-27-8 sc-317521
sc-317521A
250 mg
1 g
$200.00
$412.00
0
Biotin-PEG6-Mal
sc-496063
100 mg
$578.00
0
Mal-amido-PEG6-acid
sc-496706
100 mg
$285.00
0
Tris[3-(trimethoxysilyl)propyl] isocyanurate
A cross-linking agent and an adhesion promote
26115-70-8 sc-253798
100 ml
$93.00
0
4'-Hydroxy-2,4-dimethoxybenzophenone
A linker employed for solid-phase peptide synthesis
41351-30-8 sc-252231
5 g
$49.00
0
Azido-PEG12-NHS ester
sc-496413
100 mg
$575.00
0
N-t-Boc-2-bromoethylamine
A building block for preparing fluorinated spacers having nucleophilic and electrophilic termini
39684-80-5 sc-219234
1 g
$100.00
0
Lipoamide-PEG11-Mal
sc-496849
100 mg
$728.00
0
N-(3-Bromopropyl)phthalimide
5460-29-7 sc-250429
sc-250429A
25 g
100 g
$33.00
$113.00
0
Phthalimidoacetaldehyde
2913-97-5 sc-219615
1 g
$240.00
0
Azido-PEG1-Amine
sc-496108
100 mg
$330.00
0
Cy5.5 DBCO
sc-496174
2 mg
$405.00
0
Methotrexyl Tobramycin Amide Formate
sc-218709
1 mg
$280.00
0
Azido-PEG4-CH2CO2NHS
sc-496424
100 mg
$540.00
0
endo-BCON-PEG3-Boc-Amine
sc-496067
50 mg
$525.00
0
Mal-amido-PEG2-acid
sc-496705
100 mg
$240.00
0
3-(Fmoc-amino)propyl bromide
186663-83-2 sc-231374
5 g
$328.00
0
[4-(Diethoxy-phosphorylamino)-butyl]-phosphoramidic acid diethyl ester
sc-496208
250 mg
$390.00
0
4-(Diphenylhydroxymethyl)benzoic acid
A precursor of a new trityl linker
19672-49-2 sc-238740
1 g
$147.00
0
Triphenylphosphine oxide
A phosphine ligand used for coupling reactions, epoxidations, and Michael reactions
791-28-6 sc-397258
25 g
$20.00
0
4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid
A heterobifunctional crosslinking reagent
181148-00-5 sc-209848
10 mg
$147.00
0
Tetraethyl butane-1,4-diylbis(phosphonate)
sc-496871
250 mg
$525.00
0
Methyltetrazine-Amine hydrochloride
sc-497786
25 mg
$190.00
0
N-[4-(-Carboxycyclohexylmethyl)]maleimide
A sulfhydryl crosslinking reagent
64987-82-2 sc-212048
20 mg
$150.00
0
(S,S)-1,2-Bis[(tert-butyl)methylphosphino]ethane Bis(borane)
CAS: 203000-48-0, MF: C12H34B2P2, MW: 261.97
203000-48-0 sc-296298
100 mg
$253.00
0
Cyanine 5.5 phosphoramidite
sc-496175
50 mg
$525.00
0
DNP-PEG12-NHS ester
sc-499359
100 mg
$540.00
0
diethyl 10-bromodecylphosphonate
sc-497762
100 mg
$360.00
0
2,2'-Sulfonyldiethanol solution
A useful symmetric sulfone
2580-77-0 sc-225583
25 g
$57.00
0
Biotin-PEG3-NHS ester
A useful biochemical for proteomics research
1253286-56-4 sc-496170
250 mg
$420.00
0
1,2-Ethanediyl Bismethanethiosulfonate
A homobifunctional sulfhydryl-reactive crosslinker, 4 atom spacer arm
55-95-8 sc-208746
25 mg
$300.00
0
L-Photo-Leucine
A photoreactive amino acid analog used for protein-protein interaction studies in live cells
sc-397286
100 mg
$700.00
0
Ald-Ph-PEG3-Azide
sc-496693
100 mg
$420.00
0
Ald-Ph-PEG2-amine
sc-496085
50 mg
$420.00
0
4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid
A photoreactive aromatic diazirine
85559-46-2 sc-209896
5 mg
$280.00
0
Methyltetrazine-NHS ester
sc-496797
25 mg
$225.00
0
2-[2-(Fmoc-amino)ethoxy]ethylamine hydrochloride
An Fmoc-protected bifunctional crosslinker for proteomics research
221352-88-1 sc-225114
500 mg
$133.00
0
Azido-PEG8-PFP ester
sc-496423
100 mg
$420.00
0
Suberate Bis(sulfosuccinimidyl) Sodium Salt
A water soluble, amine reactive, homobifunctional crosslinker
127634-19-9 sc-220138
100 mg
$255.00
0
(S)-1-(4-Aminoxyacetamidobenzyl)ethylenediaminetetraacetic Acid
A bifunctional iron chelating agent
1217704-71-6 sc-220047
5 mg
$280.00
0
Mal-PEG2-alcohol
sc-496704
100 mg
$480.00
0
1,11-Diamino-3,6,9-trioxaundecane
A hydrophilic, homo-bifunctional linker
929-75-9 sc-253958
100 mg
$118.00
0
Bis(3,5-dibromosalicyl) succinate
An acetylating agent of intracellular hemoglobin
71337-52-5 sc-205228
sc-205228A
100 mg
500 mg
$21.00
$58.00
0
t-Boc-aminocaproic-N-hydroxysuccinimide
51513-80-5 sc-212985
25 mg
$300.00
0
Azido-PEG8-NHS ester
1204834-00-3 sc-496411
100 mg
$555.00
0
N-Alloc-ethylenediamine hydrochloride
MF: C6H12N2O2•HCl, MW: 180.63
sc-301276
sc-301276A
1 g
5 g
$120.00
$550.00
0
(Bis-pentafluorophenyloxycarbonylmethyl-amino)-acetic acid pentafluorophenyl ester
sc-496514
500 mg
$405.00
0
Propargyl-PEG5-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
sc-496212
100 mg
$645.00
0
PEG3-bis-(ethyl phosphonate)
sc-496501
100 mg
$390.00
0
Methoxytrityl-N-PEG8-TFP ester
sc-496686
100 mg
$420.00
0
Mal-heptanoic NHS ester
sc-498172
250 mg
$131.00
0
3,6,9,12-Tetraoxatetradecane-1,14-diyl-bis-methanethiosulfonate
212262-08-3 sc-209729
10 mg
$300.00
0
N-Boc- 2,2'-(ethylenedioxy)diethylamine
A linker reagent for the prep. of a broad variety of linked tags, monomers for polymerization, ionophores etc., e.g. biotinylation reagents
153086-78-3 sc-250447
1 g
$149.00
0
4-(t-Boc-amino)-1-butyl Bromide
164365-88-2 sc-206781
100 mg
$167.00
0
4-(Hydroxymethyl)benzoic acid
A stain used for research purposes
3006-96-0 sc-214213
sc-214213A
1 g
10 g
$57.00
$409.00
0
Thiol-PEG3-acid
sc-496480
100 mg
$510.00
0
Lipoamide-PEG3-Mal
sc-496847
100 mg
$575.00
0
N1,N1'-(1,4-phenylenebis(methylene))bis(N1-(2-aminoethyl)ethane-1,2-diamine)
sc-496870
50 mg
$525.00
0
Phosphoric acid 2-(2-{2-[2-(diethoxy-phosphoryloxy)-ethoxy]-ethoxy}-ethoxy)-ethyl ester diethyl ester
sc-496206
500 mg
$575.00
0
Mal-PEG6-PFP
sc-498201
100 mg
$681.00
0
N-Biotinylcaproylaminocaproic Acid
A biotinylated cross-linking reagent
89889-51-0 sc-212137
25 mg
$220.00
0
1,11-Diazido-3,6,9-trioxaundecane
An oligoether spacer and linker compound
101187-39-7 sc-208716
1 g
$420.00
0
Amino-PEG24-t-butyl ester
sc-498212
100 mg
$585.00
0
Tetrazine-Amine
sc-497785
25 mg
$225.00
0
Ald-Ph-PEG2-NHBoc
sc-496109
100 mg
$420.00
0
N-(Allyloxycarbonyl)ethanolamine
A building block for introducing an Alloc-protected 2-aminoethoxy group
66471-00-9 sc-253078
1 g
$250.00
0
Propargyl-PEG1-t-butyl ester
sc-498219
250 mg
$420.00
0
DNP-PEG4-NHS ester
858126-78-0 sc-499358
100 mg
$510.00
0
DPDPB
A thiol-cleavable, homobifunctional sulfhydryl-reactive crosslinker
141647-62-3 sc-237746
10 mg
$128.00
0
diethyl 8-bromooctylphosphonate
sc-497763
250 mg
$360.00
0
N-Succinimidyloxycarbonylpropyl Methanethiosulfonate
A reagent for heterobifunctional sulfhydryl cross-linking
690632-55-4 sc-219231
10 mg
$280.00
0
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline
An irreversible membrane-bound receptor antagonist
16357-59-8 sc-254228
sc-254228A
5 g
25 g
$25.00
$64.00
0
Furazolidone
A nitrofuran derivative with antiprotozoal and antibacterial activity
67-45-8 sc-218546
10 g
$47.00
0
Mal-PEG1-acid
sc-498177
100 mg
$480.00
0
Propargyl-PEG5-beta-D-glucose
sc-496859
50 mg
$390.00
0
Tetrakis(Mal-PEG4-amide)
sc-496965
25 mg
$2,100.00
0
TAMRA-Azide-PEG-Biotin
sc-496240
5 mg
$330.00
0
Ald--Ph-PEG2-acid
sc-496694
100 mg
$420.00
0
Diethyl acetylenedicarboxylate
A protein cross-linker
762-21-0 sc-234652
sc-234652A
5 g
25 g
$23.00
$71.00
0
Azido-PEG6-PFP ester
sc-496422
100 mg
$420.00
0
Methyltetrazine-PEG4-Acid
sc-497780
25 mg
$225.00
0
S-acetyl-PEG3-alcohol
sc-496825
250 mg
$345.00
0
Sulfo-Cy3-Tetrazine
sc-499255
1 mg
$240.00
0
HO-PEG4-CH2CO2t-Bu
sc-496958
250 mg
$510.00
0
Hydroxy-PEG12-t-butyl ester
sc-499265
100 mg
$525.00
0
Mal-Amido-PEG4-t-butyl ester
sc-496703
250 mg
$525.00
0
1,1-Methanediyl Bismethanethiosulfonate
A sulfhydryl cross-linking reagent
22418-52-6 sc-208706
20 mg
$280.00
0
Fmoc-Photo-Linker
CAS: 162827-98-7, MF: C28H28N2O8, MW: 520.56
162827-98-7 sc-294977
sc-294977A
100 mg
1 g
$250.00
$600.00
0
Dimethyl suberimidate dihydrochloride
A homobifunctional imidoester based crosslinker, amine reactive
34490-86-3 sc-239782
5 g
$76.00
0
(Boc-aminooxy)acetic Acid
A bifunctional linking reagent that is Boc-protected
42989-85-5 sc-212986
1 g
$70.00
0
Azido-PEG5-NHS ester
sc-496410
100 mg
$420.00
0
N-(t-Boc)ethylenediamine
57260-73-8 sc-218982
500 mg
$72.00
0
Acid-PEG13-NHS ester
sc-496134
100 mg
$540.00
0
Hydroxy-PEG6-acid
sc-496722
250 mg
$345.00
0
Biotinyl Pyridinyldithio N-Hydroxysuccinimide Alanine Ester
An antimicrobial bisulfide prodrug
1356933-91-9 sc-217765
5 mg
$280.00
0
t-boc-N-amido-PEG5-Azido
sc-496385
100 mg
$540.00
0
Biotin-PEG2-Mal
sc-496466
100 mg
$435.00
0
HBTU
A coupling reagent often used in solid phase peptide synthesis
94790-37-1 sc-203074
sc-203074A
100 g
250 g
$289.00
$578.00
0
Azido-PEG24-alcohol
sc-496397
100 mg
$693.00
0
PEG4-bis(phosphonic acid diethyl ester)
sc-496211
250 mg
$345.00
0
PEG3-bis(phosphonic acid)
sc-496500
100 mg
$480.00
0
Azido-PEG2-Amine
sc-496111
100 mg
$225.00
0
Hydroxy-PEG3-acid
sc-496950
250 mg
$345.00
0
Methoxytrityl-N-PEG12-TFP ester
sc-496687
100 mg
$465.00
0
3,6,9-Trioxaundecane-1,11-diyl-bismethanethiosulfonate
212262-02-7 sc-209728
10 mg
$300.00
0
1,17-Bisbiotinylamino-3,6,9,12,15-pentaoxaheptadecane
A biotinylated cross-linking reagent
440680-87-5 sc-206218
25 mg
$200.00
0
tert-Butyl 4-hydroxybutyrate
59854-12-5 sc-258207
500 mg
$267.00
0
8-Bromo-1-octanol
50816-19-8 sc-257015
1 g
$41.00
0
S-acetyl-PEG20 alcohol
sc-496832
100 mg
$681.00
0
Disuccinimidyl glutarate
An amine-reactive, NHS ester-based crosslinker, 7.7 angstrom spacer arm
79642-50-5 sc-285455
sc-285455A
100 mg
500 mg
$136.00
$255.00
2
Biotin-PEG11-oxyamine
sc-496266
50 mg
$525.00
0
Thiol-PEG2-acid
sc-496479
100 mg
$510.00
0
Azido-PEG2-Azide
sc-496298
100 mg
$315.00
0
DBCO-NHS
sc-499349
25 mg
$285.00
0
Fluorescein-PEG3-amine
1807539-04-3 sc-496180
10 mg
$480.00
0
N-(4-Bromobutyl)phthalimide
A useful synthesis reagent used to synthesize B-cyclodextrin derivatives
5394-18-3 sc-250430
10 g
$90.00
0
Bromo-PEG4-Azide
sc-496291
250 mg
$575.00
0
Nimustine hydrochloride
A DNA alkylator and cross-linking agent
55661-38-6 sc-202732
sc-202732A
250 mg
1 g
$30.00
$68.00
0
Tetrahydropyranyldiethyleneglycol
2163-11-3 sc-220221
250 mg
$250.00
0
1,2-Bis(dicyclohexylphosphino)ethane
A phosphine ligand
23743-26-2 sc-222793
sc-222793A
1 g
5 g
$99.00
$390.00
0
m-PEG3-NHS carbonate
sc-496145
100 mg
$390.00
0
endo-BCN-PEG2-Boc-Amine
sc-496066
50 mg
$681.00
0
Mal-PEG4-PFP
sc-498198
100 mg
$645.00
0
Azido-PEG2-PFP ester
sc-496416
100 mg
$390.00
0
3,3'-Dithiodipropionic acid di(N-hydroxysuccinimide ester)
A cleavable disulfide linkage-containing homobifunctional cross-linking reagent
57757-57-0 sc-266859
500 mg
$140.00
0
[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester
sc-496207
250 mg
$390.00
0
3-N-Maleimidobenzoic Acid N-Succinimidyl Ester
A heterobifunctional amine- and sulfhydryl-reactive crosslinker, 9.9 Angstrom spacer arm
58626-38-3 sc-209654
100 mg
$220.00
0
L-Photo-Methionine
A photoreactive amino acid analog used for protein-protein interaction studies in live cells
sc-397287
100 mg
$465.00
0
4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt
A negatively charged homobifunctional cross-linking reagent and dye
207233-90-7 sc-214282
sc-214282A
sc-214282B
25 mg
100 mg
250 mg
$41.00
$86.00
$137.00
0
1,11-Bismaleimidotetraethyleneglycol
A sulfhydryl reactive homobifunctional reagent
86099-06-1 sc-208715
25 mg
$250.00
0
Methylamino-PEG1-acid
sc-498208
100 mg
$540.00
0
tert-butyl 3-(2-(2-(2-(2-(methylamino)ethoxy)ethoxy)ethoxy)ethoxy)propanoate
sc-498211
100 mg
$420.00
0
Tri(Amino-PEG4-amide)-amine
sc-496968
50 mg
$1,485.00
0
Xantphos based ligand
349100-75-0 sc-237421
1 g
$94.00
0
Methyltetrazine-PEG5-Alkyne
sc-497783
10 mg
$225.00
0
Hydroxy-PEG8-t-butyl ester
sc-496724
500 mg
$390.00
0
S-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine
A radioionatable, cleavable, photoactivable cross linking agent
164575-82-0 sc-212808
10 mg
$280.00
0
Fluorescein-PEG2-azide
sc-496178
25 mg
$540.00
0
Sulfo-SMCC
A sulfhydryl- and amine-reactive crosslinker
92921-24-9 sc-212979
sc-212979A
sc-212979B
10 mg
100 mg
1 g
$72.00
$400.00
$1,800.00
0
Glutaraldehyde solution, 50% w/w
An amine-reactive homobifunctional crosslinker
111-30-8 sc-207716
10 ml
$55.00
0
1,4-Bis-maleimidobutane
A thiol reactive crosslinking reagent
28537-70-4 sc-208788
10 mg
$225.00
0
Propargyl-PEG4-t-butyl ester
sc-498221
250 mg
$435.00
0
N-Z-1,3-Propanediamine hydrochloride
17400-34-9 sc-253130
1 g
$60.00
0
DNP-PEG12-acid
sc-499357
100 mg
$510.00
0
Azido-PEG5-CH2CO2t-butyl ester
sc-496375
250 mg
$540.00
0
Methyl N-Succinimidyl Adipate
A masked, amino reactive, heterobifunctional crosslinking reagent
118380-06-6 sc-211886
25 mg
$220.00