Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Crosslinkers. Crosslinkers are used in the discovery of the molecular mechanisms of protein-protein interactions. Crosslinkers are either homo- or hetero-bifunctional reagents with identical or non-identical reactive groups, respectively, permitting the establishment of inter- as well as intra-molecular crosslinkages. View detailed Crosslinker specifications, including CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
N-Maleimidomethanol
A sulfhydryl reactive crosslinking reagent.
5063-96-7 sc-219170
250 mg
$220.00
0
9,9-Dimethyl-4,5-bis(di-tert-butylphosphino)xanthene
CAS: 856405-77-1, MF: C31H48OP2, MW: 498.66
856405-77-1 sc-291772
500 mg
$121.00
0
Methotrexyl Tobramycin Amide Formate
sc-218709
1 mg
$280.00
0
Propargyl-PEG3-NHS ester
sc-496278
100 mg
$405.00
0
Mal-PEG2-NHS ester
sc-498192
100 mg
$480.00
0
Amino-PEG8-alcohol
sc-496089
100 mg
$420.00
0
Bromo-PEG1-Acid
sc-496279
100 mg
$330.00
0
2-{N2-[Nalpha-Benzoylbenzoicamido-N6-6-biotinamidocaproyl]lysinylamido}ethyl-2prime-(N-sulfosuccinimidylcarboxy)ethyl Disulfide Sodium Salt
An amine reactive trifunctional cross linker
sc-229868
1 mg
$280.00
0
Mal-PEG5-NHS ester
sc-498194
100 mg
$510.00
0
N-Biotinylcaproylaminocaproic Acid
A biotinylated cross-linking reagent
89889-51-0 sc-212137
25 mg
$220.00
0
Tetrakis(Amino-PEG4-Amide)
sc-496976
25 mg
$1,800.00
0
Fluorescein-PEG3-amine
1807539-04-3 sc-496180
10 mg
$480.00
0
Amino-PEG5-alcohol
sc-496088
100 mg
$240.00
0
Amino-PEG4-CH2CO2H
sc-496680
250 mg
$555.00
0
Hydroxy-PEG16-acid
sc-496725
100 mg
$585.00
0
Mal-PEG3-NHS ester
sc-498193
100 mg
$510.00
0
3-Maleimidopropionic Acid Hydrazonium, Trifluoroacetate
359436-61-6 sc-357610
25 mg
$240.00
0
Mal-PEG4-NHS ester
sc-496142
100 mg
$510.00
0
S-acetyl-PEG6-t-butyl ester
sc-496821
250 mg
$525.00
0
Fluorescein-PEG3-(N-Boc)-amine
sc-496181
50 mg
$540.00
0
Hydroxy-PEG4-acid
sc-496952
250 mg
$345.00
0
Di(ethylene glycol) dimethacrylate
2358-84-1 sc-234545
250 ml
$56.00
0
Phenacyl 4-(bromomethyl)phenylacetate
66270-97-1 sc-253257
5 g
$113.00
0
2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6 -biotinamidocaproyl)-L-lysinyl]ethyl 2'- (N-sulfosuccinimidylcarboxy)ethyl disulfide, sodium salt
A biotin derivative cross-linking reagent
sc-223337
1 mg
$300.00
0
Hydroxy-PEG16-PFP ester
sc-496728
100 mg
$575.00
0
Diethyl acetylenedicarboxylate
A protein cross-linker
762-21-0 sc-234652
sc-234652A
5 g
25 g
$23.00
$71.00
0
6-(N-Trifluoroacetyl)caproic acid NHS
Used to temporarily block amine groups in target molecules and to extend lysine side chains to reduce steric hindrance
sc-478829
250 mg
$284.00
0
Azido-PEG4-Azide
sc-496402
100 mg
$315.00
0
m-PEG4-t-butyl ester
sc-498415
500 mg
$575.00
0
Mal-PEG2-PFP
sc-498196
100 mg
$645.00
0
N-Fmoc-1,4-butanediamine hydrobromide
CAS: 352235-99-5, MF: C19H22N2O2•HBr, MW: 391.30
352235-99-5 sc-301345
1 g
$93.00
0
N-Boc-iminodipropionic acid
143766-89-6 sc-228690
500 mg
$216.00
0
Bromo-PEG2-t-butyl ester
sc-496999
250 mg
$420.00
0
N-(2-[(t-Boc)amino]ethyl Maleimide
134272-63-2 sc-218906
500 mg
$300.00
0
Lipoamido-PEG24-acid
sc-496840
100 mg
$849.00
0
Cy5.5 DBCO
sc-496174
2 mg
$405.00
0
Triethylenetetramine
A selective Cu(II) chelator and crosslinker
112-24-3 sc-251328
sc-251328A
100 g
100 g
$29.00
$33.00
0
Benzyl-PEG3-Tos
sc-496440
500 mg
$575.00
0
Bis-PEG13-acid
sc-496953
100 mg
$575.00
0
Biotinyl Pyridinyldithio N-Hydroxysuccinimide Alanine Ester
An antimicrobial bisulfide prodrug
1356933-91-9 sc-217765
5 mg
$280.00
0
Ac-HMBA-Linker
CAS: 15561-46-3, MF: C10H10O4, MW: 194.18
15561-46-3 sc-291784
sc-291784A
5 g
25 g
$268.00
$800.00
0
PEG15
sc-498402
250 mg
$575.00
0
Methoxytrityl-N-PEG8-acid
sc-496683
100 mg
$428.00
0
4-(2-Chloropropionyl)phenylacetic acid
84098-73-7 sc-252079
1 g
$154.00
0
2-[N2-(N6-t-Boc-6-aminocaproyl)-N6-(6-biotinamidocaproy)-L -lysinylamido]ethyl Methanethiosulfonate
sc-223339
5 mg
$200.00
0
Deoxypyridinoline Chloride Trihydrochloride Salt
A collagen cross-link agent
204074-56-6 sc-214867
500 µg
$240.00
1
Bromo-PEG2-acid
sc-496280
100 mg
$330.00
0
Hydroxy-PEG3-NHS
sc-496729
100 mg
$345.00
0
Octaethylene glycol
5117-19-1 sc-228873
1 g
$102.00
0
Azido-PEG3-Maleimide kit
An azido-containing PEG linker with sulfhydryl reactivity
sc-496404
25 mg
$225.00
0
Propargyl-PEG4-NHS ester
sc-498214
100 mg
$405.00
0
(S)-(-)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine)
A compound used in C-C coupling reactions
133545-17-2 sc-229169
sc-229169A
100 mg
500 mg
$73.00
$310.00
0
Biotin-PEG2-Amine
Used in affinity purification of oligonucleotides
138529-46-1 sc-496447
100 mg
$353.00
0
m-PEG12-acid
sc-498414
100 mg
$443.00
0
Dimethyl pimelimidate dihydrochloride
A homobifunctional amine-reactive crosslinker
58537-94-3 sc-268943
sc-268943A
250 mg
1 g
$20.00
$35.00
0
Propargyl-PEG1-t-butyl ester
sc-498219
250 mg
$420.00
0
Mal-PEG1-PFP
sc-498195
100 mg
$645.00
0
Carboxy Fluorescein-PEG12-NHS
sc-496990
5 mg
$525.00
0
Hydroxy-PEG-4-t-butyl ester
sc-496998
250 mg
$180.00
0
Mal-PEG6-NHS ester
sc-496144
100 mg
$510.00
0
Amino- PEG3-t-butyl ester
252881-74-6 sc-496196
100 mg
$390.00
0
Erbstatin Analog
A stable inhibitor of EGFR tyrosine kinase
63177-57-1 sc-200511
sc-200511A
5 mg
25 mg
$81.00
$299.00
4
Amino-PEG36-alcohol
sc-496105
100 mg
$739.00
0
Cyanine 5.5 phosphoramidite
sc-496175
50 mg
$525.00
0
10-bromodecylphosphonic acid
sc-497769
100 mg
$420.00
0
1,11-Diazido-3,6,9-trioxaundecane
An oligoether spacer and linker compound
101187-39-7 sc-208716
1 g
$420.00
0
3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate
A homobifunctional sulfhydryl-reactive crosslinker
212262-04-9 sc-209726
10 mg
$280.00
0
Azido-PEG2-Azide
sc-496298
100 mg
$315.00
0
Carboxy-PEG3-mono-methyl ester
sc-496441
250 mg
$480.00
0
Bis-Mal-PEG6
sc-496716
500 mg
$630.00
0
3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane
An acetal-type crosslinking agent comonomer
78-19-3 sc-232163
5 g
$37.00
0
3-(Boc-amino)-1-propanol
58885-58-8 sc-256410
50 ml
$232.00
0
4'-Hydroxy-2,4-dimethoxybenzophenone
A linker employed for solid-phase peptide synthesis
41351-30-8 sc-252231
5 g
$49.00
0
11-Maleimidoundecanoic Acid Sulfo-N-Succinimidyl Ester
211236-68-9 sc-213588
100 mg
$240.00
0
Bis(2-diphenylphosphinoethyl)phenylphosphine
CAS: 23582-02-7, MF: C34H33P3, MW: 534.55, Purity: ≥97%
23582-02-7 sc-227362
1 g
$49.00
0
Hydroxy-PEG2-CH2CO2t-Bu
sc-496954
500 mg
$645.00
0
Bis-(2-methanethiosulfonatoethyl)dimethylammonium Chloride
sc-217766
5 mg
$280.00
0
Tris(o-methoxyphenyl)phosphine
A phosphine ligand used for catalysis
4731-65-1 sc-397666
1 g
$42.00
0
Hydroxy-PEG24-t-butyl ester
sc-498401
100 mg
$681.00
0
Methoxytrityl-N-PEG12-TFP ester
sc-496687
100 mg
$465.00
0
Azido-PEG4-beta-D-glucose
sc-496856
50 mg
$390.00
0
t-Butyl 1,3-dihydroxypropan-2-ylcarbamate
sc-496508
250 mg
$315.00
0
Bis-PEG1-NHS ester
sc-496112
50 mg
$270.00
0
Bromo-PEG3-Acid
sc-496281
100 mg
$330.00
0
(2S,2primeS,5S)-5-Hydroxy Lysinonorleucine Hydrochloride
One of the stereoisomers of 5-Hydroxylysinonorleucine, reduced collagen cross links
869111-61-5 sc-490843
0.5 mg
$350.00
0
Dichlorobis(trimethylphosphine)nickel(II)
A cross-coupling catalyst
19232-05-4 sc-252699
1 g
$50.00
0
Amino-PEG4-t-butyl ester
sc-496250
100 mg
$195.00
0
Bromo-PEG5-phosphonic acid
1446282-37-6 sc-496201
100 mg
$480.00
0
Bis-PEG1-TFP
sc-496493
250 mg
$345.00
0
Hydroxy-PEG3-PFP ester
sc-496727
100 mg
$270.00
0
Bis-PEG10-acid
sc-496951
100 mg
$575.00
0
Fmoc-Photo-Linker
162827-98-7 sc-294977
sc-294977A
100 mg
1 g
$250.00
$600.00
0
3,4-Bis-(methanethiosulfonylmethyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxy Radical
229621-21-0 sc-206698
1 mg
$350.00
0
Tris(4-chlorophenyl)phosphine
A catalyst
1159-54-2 sc-229629
1 g
$69.00
0
Amino-PEG10-t-butyl ester
sc-496189
100 mg
$525.00
0
6-(Allyloxycarbonylamino)-1-hexanol
146292-92-4 sc-239085
1 g
$78.00
0
3-(4-Hydroxymethylphenoxy)propionic acid
101366-61-4 sc-251913
1 g
$73.00
0
(R,Rprimeprime)-2,2primeprime-Bis(diphenylphosphino)-1,1primeprime-biferrocene
136274-57-2 sc-296185
sc-296185A
100 mg
500 mg
$300.00
$1,040.00
0
DBCO-PEG4-DBCO
sc-497055
25 mg
$225.00
0
Biotinylamidoethyl]-dithiomethylenemalonic Acid Bis(3-aminopropionic Acid)
sc-221364
5 mg
$350.00
0
N-Succinimidyl Myristate
A reagent used to make cationic polysaccharide compositions for transfections
69888-86-4 sc-215477
1 g
$500.00
0
4-(N-Succinimidylcarboxy)benzophenone
A benzophenone-based, amine- and photoreactive crosslinker
91990-88-4 sc-209864
25 mg
$220.00
0
Mal-PEG2-t-butyl ester
sc-496699
100 mg
$480.00
0
Tetrazine-Acid
sc-497779
25 mg
$225.00
0
Bis[2-(4-azidosalicylamido)ethyl] disulfide
A homobifunctional, long chain cross-linking reagent
199804-21-2 sc-239377
10 mg
$265.00
0
Amino-PEG36-t-butyl ester
sc-498213
100 mg
$681.00
0
1-Methanesulfonyl-11-hydroxy-3,6,9-trioxaundecane
65883-12-7 sc-213346
250 mg
$220.00
0
4-(Diphenylhydroxymethyl)benzoic acid
A precursor of a new trityl linker
19672-49-2 sc-238740
1 g
$147.00
0
Biotin-PEG4-Amine
663171-32-2 sc-496449
100 mg
$443.00
0
(R)-(+)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine)
A synthesis regeant
133545-16-1 sc-253385
sc-253385A
100 mg
500 mg
$78.00
$262.00
0
Tris[2-(diphenylphosphino)ethyl]phosphine
A catalyst used in reduction of aldehydes to alcohols
23582-03-8 sc-237398
1 g
$121.00
0
Thiol-PEG4-acid
sc-496807
100 mg
$510.00
0
TCO-PEG4-Acid
sc-498416
25 mg
$360.00
0
4-Arm PEG-Epoxide
sc-360238
1 g
$300.00
0
6-Bromo-1-hexanol
A product for proteomics research
4286-55-9 sc-239090
5 g
$79.00
0
Chloroacetamido-PEG2-NHS ester
sc-499340
50 mg
$360.00
0
(S)-Monophos
185449-80-3 sc-236829
100 mg
$20.00
0
Propargyl-PEG3-t-butyl ester
sc-498220
250 mg
$435.00
0
DBCO-NHS
sc-499349
25 mg
$285.00
0
Mal-PEG4-PFP
sc-498198
100 mg
$645.00
0
Hydroxy-PEG17-t-butyl ester
sc-499267
100 mg
$525.00
0
Tetrakis(Amino-PEG2-Amide)
sc-496974
25 mg
$1,800.00
0
2-[2-(2-t-Boc-aminoethoxy)ethoxy]ethanol
A cross-linking reagent
139115-92-7 sc-208968
250 mg
$300.00
0
Mal-PEG12-DSPE
sc-498411
25 mg
$585.00
0
N-(4-Bromobutyl)phthalimide
A useful synthesis reagent used to synthesize B-cyclodextrin derivatives
5394-18-3 sc-250430
10 g
$90.00
0
N-Boc-1,3-propanediamine
75178-96-0 sc-255338
1 ml
$124.00
0
4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
sc-496718
500 mg
$420.00
0
N-(3-Bromopropyl)phthalimide
5460-29-7 sc-250429
sc-250429A
25 g
100 g
$33.00
$113.00
0
t-Boc-N-Amido-PEG4-Azide
sc-496384
500 mg
$575.00
0
5-(3-Iodopropoxy)-2-nitrobenzyl alcohol
A photolabile linker for solid-phase oligosaccharide synthesi
185994-27-8 sc-317521
sc-317521A
250 mg
1 g
$200.00
$412.00
0
Mal-PEG4-acid
518044-41-2 sc-496147
100 mg
$345.00
0
Amino-PEG12-t-butyl ester
sc-496197
100 mg
$338.00
0
1,4-Bis(diphenylphosphino)butane monooxide
85686-00-6 sc-224937
1 g
$87.00
0
Suberic acid bis(N-hydroxysuccinimide ester)
A homobifunctional amine-reactive crosslinker, 8 atom spacer arm
68528-80-3 sc-253611
sc-253611A
500 mg
1 g
$72.00
$119.00
0
N-Z-1,5-pentanediamine hydrochloride
18807-74-4 sc-253132
500 mg
$106.00
0
t-boc-N-amido-PEG5-Azido
sc-496385
100 mg
$540.00
0
EDC hydrochloride
A water soluble carboxyl activating reagent for amide bond formation
25952-53-8 sc-219152
sc-219152A
10 g
1 g
$96.00
$21.00
0
Aminoxy-PEG8-acid
sc-496263
100 mg
$720.00
0
L-Photo-Leucine
A photoreactive amino acid analog used for protein-protein interaction studies in live cells
sc-397286
100 mg
$700.00
0
DPDPB
A thiol-cleavable, homobifunctional sulfhydryl-reactive crosslinker
141647-62-3 sc-237746
10 mg
$128.00
0
3-(Bromomethyl)benzoic acid N-succinimidylester
155863-35-7 sc-225878
1 g
$220.00
0
Sulfo-Cy5-TCO
For labeling peptides, proteins and oligos
sc-496985
1 mg
$240.00
0
Mal-amido-PEG12-NHS
sc-496713
100 mg
$540.00
0
Azido-PEG3-t-butyl ester
sc-496269
100 mg
$345.00
0
Ald--Ph-PEG3-amine
sc-496106
100 mg
$575.00
0
Sulfo-NHS-(PEG4-bismannose)-SS-biotin
A cleavable biotinylated heterobifunctional cross-linking reagent
sc-220171
250 µg
$1,300.00
0
Fluorescein-PEG4-acid
sc-496182
50 mg
$480.00
0
6-Bromohexylphosphonic acid
sc-497771
100 mg
$420.00
0
Azido-PEG2-PFP ester
sc-496416
100 mg
$390.00
0
Biotin-PEG23-azide
sc-496160
100 mg
$681.00
0