Troponin I-C Antibody (C5): sc-33728
- Troponin I-C Antibody (C5) is a mouse monoclonal IgG2b provided at 100 µg/ml
- raised against free human cardiac Troponin and/or native Troponin complex, with epitope mapping to amino acids 186-192
- recommended for detection of Troponin I, cardiac muscle of mouse, rat and human origin by WB, IP, IF and IHC(P); may cross-react with skeletal muscle Troponin I
- See Troponin I (E-9): sc-365446 for Troponin I-C antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Troponin I-C Antibody (C5). This work is in progress.
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Troponin I-C Antibody (C5) is a mouse monoclonal IgG2b antibody engineered to detect cardiac Troponin I (cTnI), also known as TNNI3, a critical regulatory protein in cardiac muscle. Anti-Troponin I-C antibody (C5) targets the epitope mapped to amino acids 186-192 of the free human cardiac Troponin I or within the native Troponin complex, ensuring precise binding and detection. Troponin I plays an essential role in the regulation of cardiac muscle contraction by inhibiting the actin-myosin interaction in the absence of calcium, thereby controlling muscle relaxation and contraction cycles. This function is vital for maintaining proper heart function and responding to physiological stress. Troponin I-C monoclonal antibody (C5) exhibits broad species reactivity, effectively recognizing cardiac Troponin I from mouse, rat, and human origins across various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Additionally, Troponin I-C (C5) antibody may cross-react with skeletal muscle Troponin I, providing versatility for studies involving different muscle types. Anti-Troponin I-C antibody (C5) is an invaluable tool for research in cardiac physiology, disease mechanisms, and the development of diagnostic assays for cardiac injury, such as myocardial infarction.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Troponin I-C Antibody (C5) | sc-33728 | 100 µg/ml | $322.00 |