TGFβ Receptor II/TGFBR2 Anticorpo D-2é um anticorpo monoclonal produzido em camundongo IgG2b κ, citado em 29 publicações, fornecido em 200 µg/ml
raised against amino acids 1-567 representing full length TFGβ RII of human origin
Anti-TGFβ Receptor II/TGFBR2 Anticorpo (D-2) é recomendado para a detecção de TGFβ RII de mouse, rat e human origem em WB, IP, IF, IHC(P) e ELISA
Anti-TGFβ Receptor II/TGFBR2 Antibody (D-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de TGFβ Receptor II/TGFBR2 (D-2): sc-17799.
m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TGFβ Receptor II/TGFBR2 Antibody (D-2) for WB and IHC(P) applications. These reagents are now offered in bundles with TGFβ Receptor II/TGFBR2 Antibody (D-2) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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A total of three members of the TGFβ family, TGFβ1, TGFβ2 and TGFβ3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFβs mediate their activity by high affinity binding to the type II receptor (TGFβ RII) transmembrane protein with a cytoplasmic serine-threonine kinase domain. TGFβ RII (TGF-beta receptor type-2), also known as TGFBR2, is a 567 amino acid single-pass type I membrane protein that contains one protein kinase domain and is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. For signaling growth inhibition and early gene responses, TGFβ RII requires both its kinase activity and association with a TGFβ-binding protein, designated the type I receptor. TGFβ RII exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 3.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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