Anti-PDGF Receptor beta/PDGFR-beta Anticorpo D-6é um anticorpo monoclonal produzido em camundongo IgG2a κ PDGF Receptor beta/PDGFR-β anticorpo, citado em 16 publicações, fornecido em 200 µg/ml
Produzido contra aminoácidos 958-1106 de PDGFR-β de human origem
Anti-PDGF Receptor beta/PDGFR-beta Anticorpo (D-6) é recomendado para a detecção de PDGF receptor type β de mouse, rat e human origem em WB, IP, IF, IHC(P) e ELISA
Anti-PDGF Receptor beta/PDGFR-beta Antibody (D-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de PDGF Receptor beta/PDGFR-β (D-6): sc-374573.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for PDGF Receptor beta/PDGFR-β Antibody (D-6) for WB and IHC(P) applications. These reagents are now offered in bundles with PDGF Receptor beta/PDGFR-β Antibody (D-6) (see ordering information below).
ChemCruz™ Produtos químicos
PDGFR Inibidores para análise funcional de respostas celulares a PDGFR
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Labware ships FedEx Ground free of charge to the contiguous US
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PDGFR-β Antibody (D-6) is a high quality monoclonal PDGFR-beta antibody (also designated CD140B antibody, PDGFR antibody, or PDGFRB antibody) suitable for the detection of the PDGFR-beta protein of mouse, rat and human origin. PDGFR-β Antibody (D-6) is available as both the non-conjugated anti-PDGFR-beta antibody form, as well as multiple conjugated forms of anti-PDGFR-beta antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Platelet-derived growth factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PGDF-AA, PDGF-AB and PDGF-BB. These three isoforms bind with different affinities to two receptor types, PDGFR-α and -β, which are endowed with protein tyrosine kinase domains. PDGFR-α can bind to both A and B subunits of PDGF, while PDGFR-β can only bind the B subunit. Ligand binding promotes either homo- or heterodimerization of the PDGF receptors in a specific manner. PDGF-AA induces the dimerization of two α receptors, PDGF-AB induces dimerization of αα and αβ and PDGF-BB induces the formation of three types of dimers, αα, αβ and ββ. Translocation of the PDGFR-β gene with the Tel gene is linked to chronic myelomonocytic leukemia (CMML), a myelodysplastic syndrome, and demonstrates the oncogenic potential of the PDGF receptors.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences