Kanamycin B sulfate CAS: 29701-07-3
MF: C18H37N5O10•H2SO4
MW: 581.59
Highly potent antibiotic against Gram-negative bacteria often used in cell culture.

Kanamycin B sulfate (CAS 29701-07-3)

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Kanamycin B sulfate is rated 5.0 out of 5 by 1.
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Nomes alternativos: Bekanamycinsulfate salt
Aplicação Kanamycin B sulfate is highly potent antibiotic against Gram-negative bacteria often used in cell culture
Numero VAT: 29701-07-3
Privada: ≥95%
Peso Molecular: 581.59
Separar por Funcao: C18H37N5O10•H2SO4
Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.
* Refere-se a Certificado de Análise para data especifica de lotes (incluindo-se o conteúdo de agua).
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Kanamycin B is an aminoglycoside with antibiotic properties that associates with bacterial ribosomal RNA. The compound is highly potent against gram-negative bacteria. Other members of the aminoglycoside group include Kanamycin A (sc-205358) and Amikacin (sc-202457). Kanamycin B has five amino groups and has a stronger association with acidic phospholipids in comparison to Kanamycin A. Studies have shown that the Kcat value of the kanamycin group is higher compared to the neomycin group.


Referencias

1. Basak, K. and Majumdar, S.K. 1973. Antimicrob. Agents Chemother. 4: 6-10. PMID: 4791483
2. Yung, M.W. and Green, C. 1987. J. Antibiot. 40: 862-867. PMID: 3610836
3. Carrier, D., et al. 1997. Biochem. Pharmacol. 53: 401-408. PMID: 9065744
4. Kwon, M., et al. 2001. Mol. Cells. 11: 303-311. PMID: 11459219
5. Norris, A.L., et al. 2010. Biochemistry. 49: 4027-4035. PMID: 20387903

Aparência :
Crystalline powder
Estado físico :
Solid
Derivado de :
Streptomyces kanamyceticus
envie :
Soluble in water (50 mg/ml), and aqueous solution (92.3 mg/ml).
Manutencao :
Store at -20° C
Ponto de fervura :
807.7° C at 760 mmHg (Predicted)
Indice de produtos :
n20D 1.67 (Predicted)
IC50 :
Bacillus subtilis: IC50 = 0.39 ug.mL-1; Staphylococcus aureus: IC50 = 1.56 ug.mL-1; Mycobacterium tuberculosis: IC50 = 2.5 ug.mL-1; Escherichia coli: IC50 = 3.13 ug.mL-1; Pseudomonas aeruginosa: IC50 = 3.13 ug.mL-1
Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.
RTECS :
WK1976500
PubChem CID :
Indice de produtos :
14: 5281
Numero de FAX :
225-170-5

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