Anti-ERK 1/2 Anticorpo C-9é um anticorpo monoclonal produzido em camundongo IgG2a κ ERK 1/2 anticorpo, citado em 337 publicações, fornecido em 200 µg/ml
Produzido contra aminoácidos 101-172 mapeamento no N-terminus de ERK 2 de human origem
Anti-ERK 1/2 Anticorpo (C-9) é recomendado para a detecção de ERK 1 and ERK 2 de mouse, rat e human origem em WB, IP, IF, IHC(P) e ELISA
Anti-ERK 1/2 Antibody (C-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de ERK 1/2 (C-9): sc-514302.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for ERK 1/2 Antibody (C-9) for WB and IHC(P) applications. These reagents are now offered in bundles with ERK 1/2 Antibody (C-9) (see ordering information below).
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possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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ERK 1/2 Antibody (C-9) is a high quality monoclonal ERK 1/2 antibody (also designated p44/42 MAPK antibody) suitable for the detection of the ERK 1/2 protein of mouse, rat and human origin. ERK 1/2 Antibody (C-9) is available as both the non-conjugated anti-ERK 1/2 antibody form, as well as multiple conjugated forms of anti-ERK 1/2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein-coupled receptor ligands and neurotransmitters can initiate MAPK signaling pathways. Activation of ERK 1 and ERK 2 requires phosphorylation by upstream kinases such as MAP kinasekinase (MEK), MEK kinase and Raf-1. ERK 1 and ERK 2 phosphorylation can occur at specific tyrosine and threonine sites mapping within consensus motifs that include the threonine-glutamate-tyrosine motif. ERK activation leads to dimerization with other ERKs and subsequent localization to the nucleus. Active ERK dimers phosphorylate serine and threonine residues on nuclear proteins and influence a host of responses that include proliferation, differentiation, transcription regulation and development. The human ERK 1 gene maps to chromosome 16p11.2 and encodes a 379 amino acid protein that shares 83% sequence identity to ERK 2.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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