Anti-cyclin B2 Anticorpo A-2é um anticorpo monoclonal produzido em camundongo IgG1 κ cyclin B2 anticorpo, citado em 15 publicações, fornecido em 200 µg/ml
Produzido contra aminoácidos 1-105 de cyclin B2 de human origem
Anti-cyclin B2 Anticorpo (A-2) é recomendado para a detecção de cyclin B2 de mouse, rat e human origem em WB, IP, IF e ELISA
Anti-cyclin B2 Antibody (A-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de cyclin B2 (A-2): sc-28303.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for cyclin B2 Antibody (A-2) for WB applications. These reagents are now offered in bundles with cyclin B2 Antibody (A-2) (see ordering information below).
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cyclin B2 Antibody (A-2) is a high quality monoclonal cyclin B2 antibody (also designated CCNB2 antibody) suitable for the detection of the cyclin B2 protein of mouse, rat and human origin. cyclin B2 Antibody (A-2) is available as both the non-conjugated anti-cyclin B2 antibody form, as well as multiple conjugated forms of anti-cyclin B2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M-phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc 1). The Cdc/cyclin enzyme is subject to multiple levels of control of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/cyclin B enzyme and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B-type cyclins not only act on M-phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B-type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
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To place an order using RMB or to ship to mainland China, please visit www.scbio.cn