Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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During mitosis, the transient assembly of the kinetochore occurs on a platform known as the centromere, a specialized chromatin structure that is comprised of various centromere proteins (CENPs). There are two multi-protein centromere complexes, known as CENPA-NAC (nucleosome-associated) and CENPA-CAD (nucleosome distal), which interact with one another to facilitate both the assembly and the activity of the centromere. CENP-M (Centromere protein M), also known as CENPM, ICEN39 or PANE1, is a 180 amino acid centromeric protein that localizes to the nucleus in non-confluent cells and to the cytoplasm in dividing or confluent cells. One of several components of the CENPA-NAC complex, CENP-M plays a crucial role in the assembly of the kinetochore and the subsequent chromosome segregation and progression through mitosis. Additionally, CENP-M is thought to be involved in the incorporation of newly synthesized CENP-A into centromeres. Three isoforms of CENP-M exist due to alternative splicing events. Isoform 3 is expressed in B-lineage chronic lymphocytic leukemia (B-CLL) cells, suggesting a possible role in carcinogenesis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn