Date published: 2025-9-8

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α-Actin Anticorpo (alpha-SM1): sc-130617

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Fichas de dados
  • alpha-Actin Anticorpo alpha-SM1é um anticorpo monoclonal produzido em camundongo IgG2a κ, citado em 69 publicações, fornecido em 200 µg/ml
  • activada contra um decapeptídeo N-terminal de smooth muscle α-Actin de human origem
  • recomendado para a detecção de smooth muscle α-Actin de mouse, rat e human origem em; Não reage com actin from fibroblasts (β-and γ-cytoplasmic), myocardium (α-myocardial), and striated muscle (α-sarcomeric)
  • disponível o conjugado para agarose para IP
  • See α-Actin (1A4): sc-32251 for additional antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG2a BP-HRP é o reagente de deteção secundária preferido para α-Actin Anticorpo (alpha-SM1) para aplicações WB and IHC(P). Este reagente é agora oferecido num pacote com α-Actin Anticorpo (alpha-SM1) (ver informações para encomenda abaixo).

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Todas as células eucarióticas expressam a actina, que frequentemente constitui até 50% da proteína celular total. Os filamentos de actina podem formar estruturas estáveis e instáveis e são componentes cruciais das microvilosidades e do aparato contrátil das células musculares. Enquanto os eucariotos inferiores, como a levedura, têm apenas um gene de actina, os eucariotos superiores têm várias isoformas codificadas por uma família de genes. Pelo menos seis tipos de actina estão presentes nos tecidos de mamíferos e se dividem em três classes. A expressão da α-actina é limitada a vários tipos de músculos, enquanto a β-actina e a γ-actina são os principais constituintes dos filamentos em outros tecidos. Os membros da pequena família GTPase regulam a organização do citoesqueleto de actina. A Rho controla a montagem das fibras de estresse de actina e a adesão focal. Rac regula o acúmulo de filamentos de actina na membrana plasmática. A Cdc42 estimula a formação de filopódios.

Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.

Informacoes sobre ordens

Nome do ProdutoNumero de CatalogoUNIDPrecoQdeFAVORITOS

α-Actin Anticorpo (alpha-SM1)

sc-130617
200 µg/ml
$316.00

Pacote do α-Actin (alpha-SM1): m-IgG2a BP-HRP

sc-546020
200 µg Ab; 10 µg BP
$354.00

α-Actin Anticorpo (alpha-SM1) AC

sc-130617 AC
500 µg/ml, 25% agarose
$416.00

I look for ZAP-70 antibodies for flowcytometry, detector PE, reactivity human, for 100 samples, this test for academic research

Asked by: Mallasi
Thank you for your question. Please contact our Technical Service Department for more information on how to receive a free 10 ug sample of this monoclonal antibody.
Answered by: Technical Service
Date published: 2022-03-28

Can this α-Actin Antibody (alpha-SM1):sc-130617 be used to stain α-smooth muscle actin in vascular endothelial cell?

Asked by: ny1164
Thank you for your question. We have tested this antibody in vascular endothelial cells so we can not confirm reactivity in this cell type.
Answered by: Technical Support
Date published: 2019-01-25

Can α-Actin (alpha-SM1): sc-130617 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: TinTin
Thank you for your question. Yes, α-Actin (alpha-SM1): sc-130617 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-15
  • y_2025, m_8, d_28, h_5CST
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Rated 4 out of 5 by from Activation of Adiponectin Receptor Regulates ProprWe used the anti-SMA antibody to determine expression of smooth muscle actin in the atortic root cross section by immunofluorescent staining, and obtained a good results. We presented the results as Figure 6D in our published paper.
Date published: 2017-08-17
Rated 5 out of 5 by from Great reactivityA great performing antibody in blotting and staining procedures. It gives off a clear and specific signal and has great reactivity. This antibody has been used to publish more than 25 times.
Date published: 2017-02-07
Rated 5 out of 5 by from It worked well in WBIt worked well in WB, IHC, IF.
Date published: 2015-10-13
Rated 4 out of 5 by from Western blot data with human aortic SMCsWestern blot data with human aortic SMCs. -SCBT QC
Date published: 2013-05-01
Rated 4 out of 5 by from Decent bands in Western with rat pulmonaryDecent bands in Western with rat pulmonary fibroblasts. -SCBT QC
Date published: 2010-03-26
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α-Actin Anticorpo (alpha-SM1) is rated 4.4 out of 5 by 5.
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