Santa Cruz Biotechnology now offers a broad range of p53 Inhibitors. p53 is a DNA-binding tumor suppressor, which upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation and cell cycle control mechanisms. p53 Inhibitors offered by Santa Cruz inhibit p53 and, in some cases, other cell death and cell differentiation related proteins. View detailed p53 Inhibitor specifications, including p53 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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Nome do Produto/Aplicacao | CAS | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS | |
---|---|---|---|---|---|---|---|
EllipticineEllipticine is a DNA intercalating inhibitor of Topo II |
519-23-3 |
sc-200878 sc-200878A |
10 mg 50 mg |
$104.00
$430.00 |
4 |
| |
Nutlin-3Nutlin-3is an apoptosis inducer and disruptor of MDM2-p53 interaction, inhibiting with a IC50 of 0.09 µM. |
548472-68-0 |
sc-45061 sc-45061A sc-45061B |
1 mg 5 mg 25 mg |
$45.00
$197.00 $739.00 |
23 |
| |
Pifithrin-α hydrobromidePifithrin-α hydrobromide is an inhibitor of p53 that reversibly blocks p53 dependent transcriptional activation and apoptosis. |
63208-82-2 |
sc-45050 sc-45050A |
5 mg 25 mg |
$106.00
$272.00 |
34 |
| |
RoscovitineRoscovitine is a potent and selective inhibitor of cyclin-dependent kinases. Selective for Cdk1, Cdk2, and Cdk5 |
186692-46-6 |
sc-24002 sc-24002A |
1 mg 5 mg |
$80.00
$245.00 |
37 |
| |
Pifithrin-alpha, p-NitroPifithrin-α, p-Nitro is a cell-permeable p53 inhibitor |
389850-21-9 |
sc-222176 |
5 mg |
$125.00
|
3 |
| |
Pifithrin-muPifithrin-µ is an inhibitor of p53 activity and HSP 70 activity |
64984-31-2 |
sc-203195 sc-203195A |
10 mg 50 mg |
$120.00
$360.00 |
4 |
| |
9-Hydroxyellipticine, Hydrochloride9-Hydroxyellipticine, Hydrochloride is a potent topoisomerase II inhibitor |
52238-35-4 |
sc-203940 sc-203940A |
10 mg 50 mg |
$510.00
$1,638.00 |
0 |
| |
Pifithrin-α, p-nitro, cyclicPifithrin-α, p-nitro, cyclic is A cell-permeable p53 inhibitor that is more potent & has a longer half-life than Pifithrin-α. |
60477-38-5 |
sc-222177 sc-222177A sc-222177B sc-222177C |
5 mg 10 mg 25 mg 50 mg |
$164.00
$300.00 $600.00 $1,100.00 |
1 |
| |
Cyclic Pifithrin-alpha hydrobromideCyclic Pifithrin-α hydrobromide is a cyclic analog of pifithrin-α |
511296-88-1 |
sc-361164 sc-361164A |
10 mg 50 mg |
$222.00
$915.00 |
1 |
| |
SJ 172550SJ 172550 is a MDMX inhibitor that inhibits MDMX-p53 interaction in cultured cells |
431979-47-4 |
sc-357403 sc-357403A |
10 mg 50 mg |
$169.00
$709.00 |
1 |
| |
(+)-Nutlin-3(+)-Nutlin-3 is a potent inhibitor of p53-Mdm2 interaction |
675576-97-3 |
sc-222085 sc-222085A |
500 µg 1 mg |
$90.00
$118.00 |
0 |
| |
(-)-Nutlin-3(–)-Nutlin-3 is an inhibitor of p-53-MDM2 interaction |
675576-98-4 |
sc-222086 sc-222086A |
1 mg 5 mg |
$113.00
$203.00 |
2 |
|