ZotarolimusA tetrazole-containing Rapamycin analog

Zotarolimus (CAS 221877-54-9)

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Application: A tetrazole-containing Rapamycin analog
CAS Number: 221877-54-9
Molecular Weight: 966.22
Molecular Formula: C52H79N5O12
* Refer to Certificate of Analysis for lot specific data (including water content).
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Zotarolimus is a tetrazole-containing Rapamycin analog which is used as animmunomodulator, and is useful in the treatment of restenosis, immune, and autoimmune diseases.


References

Moses, J., et al.: N. Engl. J. Med., 349, 1315 (2003), Ako, J., et al.: J. Am. Coll. Cardiol., 46, 1002 (2005), Wagner, et al.: Bioorg. Med. Chem. Lett., 15, 5340 (2005), Hong, M., et al.: Circulation, 113, 414 (2006),

Storage :
Store at 4° C
Melting Point :
100-105°C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9876378
SMILES :
C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@@H]([C@@H](C4)OC)N5C=NN=N5)C)/C)O)OC)C)C)/C)OC

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Certificate of Analysis

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